Guest guest Posted February 25, 2012 Report Share Posted February 25, 2012 ----- Forwarded Message ----To: CAChitter Sent: Sat, February 18, 2012 7:18:09 PMSubject: lethal dose of PEG http://www.mindfully.org/Plastic/Polymers/Polyethylene-Glycols-PEGs.htm The mean lethal doses of PEG are presented in the table.03Table Mean lethal doses of PEGs (g/kg BW).Polyethylene Glycols Mice Rats Guinea pigs Rabbits 200 (insoluble) 33.9-38.3 28.9 16.9 14.1-19.9 300 (insoluble) 31.0 27.5-31.1 19.6-21.1 17.3-21.1 400 (insoluble) 28.9-35.6 12.9-30.2 15.7-21.3 22.3 600 (insoluble) 35.6-47.0 38.1 28.3 18.9 1000 (50%aqu.sol.) >50 42.0 22.5-41.0 >50 4000 (50%aqu.sol.) >50 >50 46.4-50.9 >50 6000 (50%aqu.sol.) >50 >50 >50 >50 9000 (50%aqu.sol.) >50 >50 >50 >50 Carcinogenicity. Exposure to PEG resulted in vaginal tumors and a weak tumor initiator effect in mice.5,8,9 if the additive is an addition polymer of ethylene oxide and water with a mean molecular mass of 200 to 9,500 and if PEG contains no more than 0.2% by weight of the ethylene and diethylene glycols and if its molecular mass is 350 or higher and no more than 0.5% by weight of the total of ethylene and diethylene glycols and if its mean molecular mass is below 350. Quote Link to comment Share on other sites More sharing options...
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