Guest guest Posted March 27, 2008 Report Share Posted March 27, 2008 Isn't it peculiar, GIRLS are affected more so than the boys wonder what the difference is relating to the blood-brain barrier is between boys and girls? ......hmmm http://lib.bioinfo.pl/auth:,DG Predictors of abdominal pain in schoolchildren: A 4-year population- based prospective study. [My paper] A El-Metwally, Smita Ls Halder, G , J Macfarlane, Gareth T BACKGROUND: Chronic abdominal pain (CAP) is common among schoolchildren and is a major cause of school absenteeism and medical care visits. On physical examination, an obvious organic cause is seldom found and risk factors contributing to onset are still largely unknown. AIMS: To determine the frequency of onset of CAP in schoolchildren and to investigate risk factors for its development. METHODS: 1411 schoolchildren aged 11-14 years were recruited from schools in North-West England. Information was collected regarding recent pain symptoms and a group of children free of abdominal pain were identified. Information was collected on potential risk factors for the development of CAP: weight, height, headache, sore throat, low back pain, daytime tiredness, level of physical activity, lifestyle factors, psychosocial factors and enjoyment of school. Participants were followed-up 1 and 4 years later and new episodes of CAP were identified. RESULTS: 22% reported new-onset abdominal pain at 1-year follow-up which persisted at 4-year follow-up (CAP). Development of CAP was almost three times higher in girls than boys (34% versus 13%; chi2: 26.0; p<0.001). In girls, reporting headache at baseline was the only predictive factor for CAP onset: those who reported headaches on >7days in the month prior to the baseline survey experienced a doubling in the risk of symptom onset (relative risk: 2.1; 95% confidence interval: 0.95-4.7). In contrast, in boys, development of CAP was independently predicted by: daytime tiredness (3.0; 1.2-7.6), lack of school enjoyment (2.0; 0.95-4.2), adverse psychosocial exposures (2.3; 1.2-4.5) and taller stature (1.9; 0.8- 4.5). CONCLUSION: Our results suggest that over one-fifth of adolescent schoolchildren experience new-onset non-self limiting abdominal pain over a one-year period, the majority of whom are girls. In terms of factors for which intervention is possible, previous somatic symptom reporting predicts future abdominal pain in girls; whereas, in boys, both somatic symptoms reporting and psychosocial factors predict future pain. These risk factors indicate a possible mechanism for understanding the development of CAP, and might have important implications for both primary and secondary preventive strategies. Quote Link to comment Share on other sites More sharing options...
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