Re: Key important points to remember about this group

[Guest guest]

I want to ask you the simple question - If Miralax is such a wonderful drug then why does every horrible symptom improve when the drug is removed? I was on the stuff for 3 months and went through hell, I still have dental problems that started at that time.

This is a group of intelligent people that come to give opinions and ask for suggestions for help.

Have you read about the little Bradshaw boy?

From: concernedparent1978@...

Sent: Wednesday, June 13, 2012 1:01 PM

To: miralax

Subject: Key important points to remember about this group

* PEG 8000 and PEG 6000 are not the same as PEG 3350, and any information you have found regarding the metabolism, uses, cautions, etc about a different PEG cannot be extrapolated to assuming characteristics for PEG 3350.* Providing unsubstantiated advice to parents whose primary concern is the safety of their child is irresponsible. Many of the suggestions (natural and medicinal) are completely contraindicated for use in children. Even if you have tried one of these harmful therapies in your child, please do not provide this advice for other parents. (SENNA IS CONTRAINDICATED IN CHILDREN AND VERY HABIT FORMING - it is known to alter the child's normal GI tract motility). * In addition, most of the therapies you have decided to share on this message board have also not been proven to be safe in children under the age of 18. Why would you exchange one treatment option for another with the same problem?* Polyethylene glycol is NOT the same as ethylene dioxide, ethylene glycol, or diethylene glycol and and information should not be mistaken as such. * Blaming your child's psychiatric issues on a common bulk forming laxative is delusional. Look at the bigger picture. You are doing nothing to help your child by blaming the wrong cause. And even worse, you are causing alarm for other parents whose children may be benefiting from following their doctor's advice. There are many confounding factors that may be contributing to a patient's side effects. Please don't generalize your "experience" to those of all patients.* Studies have been published in reputable journals addressing the safety and efficacy of Miralax in children for up to a year. Please reference these articles for accurate information regarding this drug:REFERENCESBell EA, Wall GC. Pediatric Constipation Therapy Using Guidelines and Polyethylene Glycol 3350. The ls of Pharmacotherapy. 2004. 686-693Shah S, Prematta T, Adkinson FN, Ishmael FT. Hypersensitivity to Polyethylene Glycols. J Clin Pharmacol. 8 May 2012.Loeing-Baucke V. Polyethylene Glycol Without Electrolytes for Children with Constipation and Encopresis. J Pediatr Gastr Nutr. April 2002. 34:372-377Pashankar DS, Loening-Baucke V, Bishop WP. Safety of Polyethylene Glycol 3350 for the Treatment of Chronic Constipation in Children. Arch Pediat Adol Med. July 2003. 661-664

[Guest guest]

I would like to kindly say that you are in the wrong place. Those that have signed up to this group are here willingly because we as parents know that this drug has negatively effected our children. Nobody forced our hand to join this group. Thank you for your information, but please kindly exit as you are not of the same mindset as those in this group. You are welcome to form your own pro mirilax group if you'd like. Nobody will make me believe differently about this drug because my child lived it. I could care less about the references you list. It is not going to change my mind about what I saw from my daughter while on this drug. Too many times there have been drugs that were eventually pulled off of the shelves that

previously were recommended and came w/ similar positive reference lists. Until you live it w/ your child, you have no business scorning others who ARE acting as responsible parents by making the decision to discontinue a drug they know is causing harm to their child. It woudl be irresponsible to continue a drug in such a manner as a parent. It's quite posssible the drug effects different children in different ways and for most of us...that's exactly what has occurred. We all had a negative experience with it for our children. I wish you well, but again I want to be sure you know that we are all friendly here to one another and do not welcome negativity by somebody that considers many of us "irresponsible and delusional". I mean no disrespect with what I say to you and I hope you do not take it as such. To: miralax Sent: Wednesday, June 13, 2012 2:01 PM Subject: Key important points to remember about this group

* PEG 8000 and PEG 6000 are not the same as PEG 3350, and any information you have found regarding the metabolism, uses, cautions, etc about a different PEG cannot be extrapolated to assuming characteristics for PEG 3350.

* Providing unsubstantiated advice to parents whose primary concern is the safety of their child is irresponsible. Many of the suggestions (natural and medicinal) are completely contraindicated for use in children. Even if you have tried one of these harmful therapies in your child, please do not provide this advice for other parents. (SENNA IS CONTRAINDICATED IN CHILDREN AND VERY HABIT FORMING - it is known to alter the child's normal GI tract motility).

* In addition, most of the therapies you have decided to share on this message board have also not been proven to be safe in children under the age of 18. Why would you exchange one treatment option for another with the same problem?

* Polyethylene glycol is NOT the same as ethylene dioxide, ethylene glycol, or diethylene glycol and and information should not be mistaken as such.

* Blaming your child's psychiatric issues on a common bulk forming laxative is delusional. Look at the bigger picture. You are doing nothing to help your child by blaming the wrong cause. And even worse, you are causing alarm for other parents whose children may be benefiting from following their doctor's advice. There are many confounding factors that may be contributing to a patient's side effects. Please don't generalize your "experience" to those of all patients.

* Studies have been published in reputable journals addressing the safety and efficacy of Miralax in children for up to a year. Please reference these articles for accurate information regarding this drug:

REFERENCES

Bell EA, Wall GC. Pediatric Constipation Therapy Using Guidelines and Polyethylene Glycol 3350. The ls of Pharmacotherapy. 2004. 686-693

Shah S, Prematta T, Adkinson FN, Ishmael FT. Hypersensitivity to Polyethylene Glycols. J Clin Pharmacol. 8 May 2012.

Loeing-Baucke V. Polyethylene Glycol Without Electrolytes for Children with Constipation and Encopresis. J Pediatr Gastr Nutr. April 2002. 34:372-377

Pashankar DS, Loening-Baucke V, Bishop WP. Safety of Polyethylene Glycol 3350 for the Treatment of Chronic Constipation in Children. Arch Pediat Adol Med. July 2003. 661-664

[Guest guest]

If I may add: My daughter was clearly failing to thrive while on Miralax for 8.5 months. She didn't grow an inch nor gain an ounce. In fact, she lost an ounce. This during a period in her development when she should have been growing in length and gaining weight at a measurable pace. She also suffered other side-effects. Once the Miralax was discontinued, she started to grow again, almost immediately. She gained an inch in height the first month she was off Miralax and continues to grow at a healthy clip, but because of the 8.5 months she lost, she is much shorter than ALL of her peers. She is currently 4.5 years old and could easily pass for a 3 year old.I also have a question for you: If Miralax is safe for

children, why does the manufacturer say not to use in children 17 and under? If Miralax is safe for long-term use, why does the manufacturer state not to use for longer than 7-10 days? Why isn't the manufacturer using the studies you cite to hock this drug officially?As far as I am concerned, this group helped SAVE my child from God knows what else. She now leads a constipation-free life because information I found here and followed allowed her to do so. You mention Senna as being contra indicated for use in children and if you had read ALL of the information exchanged on this board, you would have realized that there have been mention of senna possibly not being good for long-term use, etc., but I'd like to see where it says that it's contraindicated for use in children.I found

myself shaking my head reading your statement. Let me say it again: this discussion board helped save my child. It was not her pediatrician who suggested that I try lactose-free milk (or probiotics or plum smart juice or any number of natural solutions) instead of Miralax. It was someone on this group who did so. Instead of a chemical solution, I found a natural one. It was on this board I learned of all the dietary solutions that worked for her.I understand that as a person who is vested in the pharmaceutical world, you would find yourself trying to defend your profession, but please, don't make unsubstantiated allegations. While we may not be scientists or physicians, we are most certainly NOT hysterical or irrational people. We are concerned parents who witnessed the negative side-effects that this drug had on our children. All of us found this

group while looking for a solution OTHER than Miralax BECAUSE of the side-effects we experienced or witnessed, and most of us thankfully found it and succeeded in saving our children or ourselves from the disturbing side-effects of this drug. Lillu Tesfa To: miralax Sent: Wednesday, June 13, 2012 3:10 PM Subject: Re: Key important points to remember about this

group

I want to ask you the simple question - If Miralax is such a wonderful drug then why does every horrible symptom improve when the drug is removed? I was on the stuff for 3 months and went through hell, I still have dental problems that started at that time.

This is a group of intelligent people that come to give opinions and ask for suggestions for help.

Have you read about the little Bradshaw boy?

From: concernedparent1978@...

Sent: Wednesday, June 13, 2012 1:01 PM

To: miralax

Subject: Key important points to remember about this group

* PEG 8000 and PEG 6000 are not the same as PEG 3350, and any information you have found regarding the metabolism, uses, cautions, etc about a different PEG cannot be extrapolated to assuming characteristics for PEG 3350.* Providing unsubstantiated advice to parents whose primary concern is the safety of their child is irresponsible. Many of the suggestions (natural and medicinal) are completely contraindicated for use in children. Even if you have tried one of these harmful therapies in your child, please do not provide this advice for other parents. (SENNA IS CONTRAINDICATED IN CHILDREN AND VERY HABIT FORMING - it is known to alter the child's normal GI tract motility). * In addition, most of the therapies you have decided to share on this message board have also not been proven to be safe in children under the age of 18. Why would you exchange one treatment option for another with the same problem?* Polyethylene glycol is NOT the same as ethylene dioxide, ethylene glycol, or diethylene glycol and and information should not be mistaken as such. * Blaming your child's psychiatric issues on a common bulk forming laxative is delusional. Look at the bigger picture. You are doing nothing to help your child by blaming the wrong cause. And even worse, you are causing alarm for other parents whose children may be benefiting from following their doctor's advice. There are many confounding factors that may be contributing to a patient's side effects. Please don't generalize your "experience" to those of all patients.* Studies have been published in reputable journals addressing the safety and efficacy of Miralax in children for up to a year. Please reference these articles for accurate information regarding this drug:REFERENCESBell EA, Wall GC. Pediatric Constipation Therapy Using Guidelines and Polyethylene Glycol 3350. The ls of Pharmacotherapy. 2004. 686-693Shah S, Prematta T, Adkinson FN, Ishmael FT. Hypersensitivity to Polyethylene Glycols. J Clin Pharmacol. 8 May 2012.Loeing-Baucke V. Polyethylene Glycol Without Electrolytes for Children with Constipation and Encopresis. J Pediatr Gastr Nutr. April 2002. 34:372-377Pashankar DS, Loening-Baucke V, Bishop WP. Safety of Polyethylene Glycol 3350 for the Treatment of Chronic Constipation in Children. Arch Pediat Adol Med. July 2003. 661-664

[Guest guest]

I am sorry that you have misinterpreted my information. I would like to inform you that I am in no way pro-Miralax and I also would like to point out that I do believe that some of the side effects could very well be attributed to Miralax. As a medical professional I strive to put the needs of my patients first and I long to ensure that the care they get is the best possible. My concern is that there are many people who are having symptoms that could be attributed to various other causes. The aspect that is of most concern to me is that there have been recommendations to use alternative therapies which can be very dangerous for children. I apologize if I have offended anyone my goal is only to bring to light the need for medical professionals to help you work through some difficult problems you are facing. To: "miralax " <miralax > Sent: Wednesday, June 13, 2012 2:27 PM Subject: Re: Key important points to remember about this

group

I would like to kindly say that you are in the wrong place. Those that have signed up to this group are here willingly because we as parents know that this drug has negatively effected our children. Nobody forced our hand to join this group. Thank you for your information, but please kindly exit as you are not of the same mindset as those in this group. You are welcome to form your own pro mirilax group if you'd like. Nobody will make me believe differently about this drug because my child lived it. I could care less about the references you list. It is not going to change my mind about what I saw from my daughter while on this drug. Too many times there have been drugs that were

eventually pulled off of the shelves that

previously were recommended and came w/ similar positive reference lists. Until you live it w/ your child, you have no business scorning others who ARE acting as responsible parents by making the decision to discontinue a drug they know is causing harm to their child. It woudl be irresponsible to continue a drug in such a manner as a parent. It's quite posssible the drug effects different children in different ways and for most of us...that's exactly what has occurred. We all had a negative experience with it for our children. I wish you well, but again I want to be sure you know that we are all friendly here to one another and do not welcome negativity by somebody that considers many of us "irresponsible and delusional". I mean no disrespect with what I say to you and I hope you do not take it as such. To: miralax Sent: Wednesday, June 13, 2012 2:01 PM Subject: Key important points to remember about this group

* PEG 8000 and PEG 6000 are not the same as PEG 3350, and any information you have found regarding the metabolism, uses, cautions, etc about a different PEG cannot be extrapolated to assuming characteristics for PEG 3350.

* Providing unsubstantiated advice to parents whose primary concern is the safety of their child is irresponsible. Many of the suggestions (natural and medicinal) are completely contraindicated for use in children. Even if you have tried one of these harmful therapies in your child, please do not provide this advice for other parents. (SENNA IS CONTRAINDICATED IN CHILDREN AND VERY HABIT FORMING - it is known to alter the child's normal GI tract motility).

* In addition, most of the therapies you have decided to share on this message board have also not been proven to be safe in children under the age of 18. Why would you exchange one treatment option for another with the same problem?

* Polyethylene glycol is NOT the same as ethylene dioxide, ethylene glycol, or diethylene glycol and and information should not be mistaken as such.

* Blaming your child's psychiatric issues on a common bulk forming laxative is delusional. Look at the bigger picture. You are doing nothing to help your child by blaming the wrong cause. And even worse, you are causing alarm for other parents whose children may be benefiting from following their doctor's advice. There are many confounding factors that may be contributing to a patient's side effects. Please don't generalize your "experience" to those of all patients.

* Studies have been published in reputable journals addressing the safety and efficacy of Miralax in children for up to a year. Please reference these articles for accurate information regarding this drug:

REFERENCES

Bell EA, Wall GC. Pediatric Constipation Therapy Using Guidelines and Polyethylene Glycol 3350. The ls of Pharmacotherapy. 2004. 686-693

Shah S, Prematta T, Adkinson FN, Ishmael FT. Hypersensitivity to Polyethylene Glycols. J Clin Pharmacol. 8 May 2012.

Loeing-Baucke V. Polyethylene Glycol Without Electrolytes for Children with Constipation and Encopresis. J Pediatr Gastr Nutr. April 2002. 34:372-377

Pashankar DS, Loening-Baucke V, Bishop WP. Safety of Polyethylene Glycol 3350 for the Treatment of Chronic Constipation in Children. Arch Pediat Adol Med. July 2003. 661-664