Guest guest Posted June 4, 2012 Report Share Posted June 4, 2012 I just obtained a copy of Dr. ' book, " DMSO, The Complete Up-to-Date Guidebook' (1993). In it I found interesting that he said the only difference between industrial grade DMSO and pharma grade was this: " Basically, prescription DMSO goes through two procedures that " over-the-counter " DMSO doesn't. First it is sterilized by filtration. Second, it is pyrogen tested. To sterilize DMSO, the product is passed through a very fine filter that removes any particles the size of bacteria and larger. Most researchers, clinicians and medical professionals consulted, questioned the need for sterilization. If you remember DMSO is bacteriostatic at concentrations of 35% or above; at these concentrations, it stops bacteria growth. Pyrogen testing is a costly and time consuming procedure. A pyrogen is any substance that causes a fever. To test a batch of DMSO for pyrogens, laboratory animals treated with the drug and then their temperatures are monitored on a regular basis. This procedure is felt by many to be another instance of FDA " overkill " . Most informed authorities agree that pyrogen testing is definitely not necessary for DMSO intended for topical use. Many even question its necessity for DMSO used to treat interstitial cystitis by catheter. " I say to this, if this is true, one can easily filter over-the-counter DMSO with .22 micron filter set-ups and save hundreds of dollars. doug Quote Link to comment Share on other sites More sharing options...
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