Statistics adverse reactions Genelex web site

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From Genelex website:

According to the Journal of the American Medical Association

(JAMA), there are over 100,000 fatal and 2.2 million serious but non-fatal

adverse drug reactions every year in the U.S. These reactions are most

common in patients taking multiple medications. JAMA also points out that

fifty-nine percent of drugs most commonly cited in adverse drug reaction studies

are processed by enzymes that are affected by inherited DNA variations (JAMA

286:2270 2001) Adverse drug reactions, usually called side effects, are a

long-standing and largely neglected major medical problem. These are not

medical errors and occur within the FDA approved dosage and labeling

recommendations. The reported problems with antidepressant-induced teen

suicides, the recalls of Vioxx and Baycol and the upgrading of Accutane

monitoring by the FDA are the tip of the iceberg.

Incidence

of Adverse Drug Reactions

-ADRs are the fourth to sixth greatest killer in US with more than

100,000 deaths per year; and 2.2 million serious adverse reactions per year

according to a 1998 Journal of the American Medical Association report. (JAMA

279:1200 1998) This study is a meta analysis of 39 research reports published

from 1966 to 1996.

-10.2% of the 548 most recently FDA approved medications were

subsequently withdrawn from the market or given a black box warning. JAMA

287:2215 2002

-The GAO reports that 51% of new drugs have serious, undetected

adverse effects at the time of approval.

-Of the best selling prescription drugs, 148 can cause depression,

133 hallucinations or psychoses, 105 constipation, 76 dementia, 27 insomnia and

36 Parkinsonism. "Worst Pills Best Pills: A Consumers Guide to Avoiding

Drug-Induced Death or Illness," third edition, 1999.

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WE SHOULD BE MINDFUL OF EVERYTHING WE PUT INTO OUR BODIES!