Hypkalemia PEG 3350

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Signs and symptomsMild hypokalemia is often without symptoms, although it may cause a small elevation of blood pressure,[3] and can occasionally provoke cardiac arrhythmias. Moderate hypokalemia, with serum potassium concentrations of 2.5-3 mEq/L (Nl: 3.5-5.0 mEq/L), may cause muscular weakness, myalgia, and muscle cramps (owing to disturbed function of the skeletal muscles), and constipation (from disturbed function of smooth muscles). With more severe hypokalemia, flaccid paralysis and hyporeflexiamay result. There are reports of rhabdomyolysis occurring with profound hypokalemia with serum potassium levels less than 2 mEq/L. Respiratory depression from severe impairment of skeletal muscle function is found in many patients.Some electrocardiographic (ECG) findings associated with hypokalemia include flattened or inverted T waves, a U wave, ST depression and a wide PR interval. Due to prolonged repolarization of ventricular Purkinje fibers, a prominent U wave occurs, that is frequently superimposed upon the T wave and therefore produces the appearance of a prolonged QT interval.[4][edit]http://www.druginformation.com/RxDrugs/P/PEG-3350,%20Na%20Sulfate,%20NaCl,%20KCl,%20Na%20Ascorbate%20and%20Ascorbic%20Acid%20For%20Oral%20Solution.html