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Weaning Off Sinemet

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Several members have indicated that a time may come for weaning off

Sinemet. Others have suggested that maintaining a small dose might be

wise. Naturally each case is different and caregivers will make

changes in consultation with physicians.

From my perspective, I would ask a lot of questions if it was

suggested that stop it entirely. In 2002 he had a parkinsons

meds honeymoon. He was weaned off all his PD meds in an inpatient

setting and it almost killed him. Not to mention his dementia went off

the charts because he was hospitalized and ende dup needing lots of

antibiotics.

His muscles became so rigid he was in great physical distress. He

could not move his bowels because the natural contractions that move

stool stopped, and he contracted pneumonia. The medicines for

pneumonia led to renal failure, and also killed all the good

intestinal flora so that his constipation was followed by a botulism

related diahrrea that almost killed him.

Note that all this was under the care of neurologists who gradually

returned him to his sinemet, with less comtan and added seroquel. I

will consider lessening his dopamine producing and dopamine agonist

drugs again if a doctor advises, but I will have many more questions

in advance, and will question dropping it completely. I will need to

be convinced that akinesia with it's bad effects will not be a result.

Kathy

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