Hyponatremia (low blood sodium) due to reset osmostat in DLB

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Hyponatremia (low blood sodium) due to reset osmostat in DLB

To the Editor: Various central nervous system disorders can

cause the syndrome of inappropriate antidiuresis (SIAD).1

Reset osmostat is considered a subtype of SIAD, in which

unknown central processes lower the osmotic threshold for

antidiuretic hormone (ADH) release, resulting in a continuously

lower serum sodium concentration.1,2

We report a case of hyponatremia due to reset osmostat

in probable dementia with Lewy bodies (DLB), illustrating

how the encountered diagnostic challenges may serve as

teaching points.

Read more here:

http://www.lewybodydementia.org/forum/viewtopic.php?t=738