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chemical and bacterial inflammation/ decreased thyroid hormones

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Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic

Granulocytes in Response to Acute Bacterial Infection

(http://www.liebertonline.com/doi/abs/10.1089/thy.2008.0090)

Conclusion: Infiltrating granulocytes during acute bacterial infection

express D3. Our work supports the hypothesis that D3 plays an important

role during chemical and bacterial inflammation. Whether the resulting

decreased local bioavailability of thyroid hormones or rather the

increased local availability of iodide is an important element of the

innate immune response remains to be studied.

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