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Unlikely cousins?

Montana State University - United States

http://www.montana.edu/cpa/news/nwview.php?article=6569

Humans and fungus are genetically very similar, which creates

problems when scientists design antifungal drugs, says

Cramer, assistant professor of veterinary molecular biology at MSU.

Since fungus and humans have many of the same genes, drugs that can

kill fungi often have detrimental side effects on humans. It's a

different story with bacteria and viruses, however. The genetic

makeup of bacteria and viruses is different enough from humans' that

drugs to fight them are usually less threatening to humans. That

explains in part why more drugs are available to fight bacteria and

viruses than fungi, Cramer said. Cramer discussed the close

relationship between humans and fungi after publishing a recent

paper about a gene that regulates the resistance of a common disease-

causing mold to antifungal drugs.

Boswell, (406) 994-5135 or evelynb@...

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