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Hi Jenni

Your doctor can order the blood work. Depending on what your doctor's office

is capable of doing, they could do it in the office, or you may need to go to a

lab. But the doctor will have to make the order for the test.

But before you talk with your doctor, here is some important info to take

along.

1st: Because people with MDS have a percentage of cells with the extra 21st

chromosome and the remaining cells are unaffected, it is very important that the

doctor tests more than the standard 20 cells. In a lot of cases, the affected or

unaffected cells are not discovered with this small amount of cells tested. So,

we recommend that 100-500 cells be tested. This will give you a better chance of

seeing the extra chromosome if it is there.

2nd: In some cases, an individual with MDS only has the affected cells located

in the skin. Some labs will take a cheek swab for this test while other prefer

to deaden an area and take a small sample of skin from behind the ear or on the

thigh. If a blood test does not reveal the extra chromosomes we recommend that a

skin test is done.

3rd: The average age for individuals to be diagnosed with MDS is 1-4 yrs.

However, because of IMDSA's efforts in educating the public on MDS, these

numbers are changing and now more babies are being diagnosed at birth or soon

after. The reason for the misdiagnosis is usually the lack of characteristics

associated with Down syndrome and the lack of education in the medical

community. Just this week one of our new family's child was diagnosed at 7 yrs

old. So... this isn't impossible for your child to have MDS. But often times the

doctor will just know about Down syndrome and not understand the faint

characteristics.

I hope some of this helps. If you have other questions just ask away!

Kristy

Randal wrote:

Does the dr do the bloodwork or would I have to go to a specialist?

Thanks-

Jenni

Re: Welcome !

To: MosaicDS

Date: Tuesday, September 2, 2008, 4:07 PM

Thankyou for the welcome. A little bit of history...My last

pregnancy

before this child ended at 18 weeks. The baby had several things

wrong

with her. It was either Trisomy 18 or 's. We never found out

for

sure.

When was born last October, I could not get him to nurse in

the hospital. He would turn away like he didn't even want to try. I

have nursed all of my children for one year, so I felt like he

should

catch on pretty quick..BUT he didn't. I cried over and over and the

drs thought if I got home in my own environment, things would go

more

smoothly. He was loosing weight, but I was not going to give in and

give him the bottle. So, After a few weeks, he caught on.

Other things I noticed different (compared to my other children)

from

the beginning. When I would go to pick him off the changing table,

he

was kind of floppy. I just compensated and would push in around his

chest to lift him instead of directly under his arms. My mom told me

she thought it was strange that he didn't look at our hairlines like

most babies, but he looked beyond our faces into the ceiling.

Anyway...around 4 months old, I tried to introduce him to juice. He

didn't want anything to do with it. 5 months old-he rolled over from

front to back a few times(I figured he was on track because of

this).

He never would roll from his back to front. Ard 6 months, I tried

baby

food and he would have nothing to do with it. so I waited and tried

over and over again. Finally, ard 7 months, he started eating baby

food. I was talking to a friend about a month ago and her baby was

younger than mine and was eating cheerios! I thought then that he

was

definitely behind. Anytime I give him a piece of rice or anything

small, he would gag and spit up all (usually 2 jars) of baby food.He

sat up really late compared to average children. He still wasn't

crawling at 9 months, so I started thinking maybe all of these

things

were related. I made an appt with the dr and right before we went it

at 10 months, he started rolling from his back to front and

crawling!

I went ahead and took him.

He said that he had the 'whatever' fold in his eye, but he didn't

have

a crease in his hands. He said that the pediatrician would know more

about syndromes and could make a better diagnosis if he indeed had

something going on. So, when I came home, I started researching and

it

seems that he may have MDS I am waiting for the Dr to call me back

for

an appt and I am going nuts! I have cried a little, because I don't

want anything to be wrong. I can handle having a special needs

child,

I just don't want him to have health issues. He is the sweetest,

happiest baby (he wasn't the first few months) and we all love him

dearly. HE is spoiled rotten!

Other things that I can look back and wonder about...

When he was born, his neck was thick with extra skin. Both me and my

husband noticed it, but it disappeared in few weeks or so.

He wiggles his hands (like crazy) if he is sitting still (kinda

strange)

He had hiccups all the time! I asked the dr if it could be reflux

and

he said no. He had them all day and night.

Well, anyway, any advice that you might have would be welcome-advice

for me or questions I might ask the dr.

Thanks so much-

>

> Welcome to our family . I am so glad you have joined us.

Please tell us more about your son. What other things (if any) lead

you to think he has MDS?

> Please feel free to ask any questions you have here. We will all

be happy to share our experiences.

>

> Kristy

> Mom to Arron 26, 23, Tim 22 MDS, Stevan 21 and Garrett 12

>

>

>

>

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  • 4 weeks later...

Hi-

The Dr just called and said that the tests came back 'normal'. I asked the nurse

how many cells were tested. She said they analyzed 22 and karyotyped 5. Was all

of this a waste of time? Do I need to push for more to be tested and ask to be

referred to a geneticist? I am confused.

Thanks-

(mom to -11 months)

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Hi

Yes, it was definately a waste of time! I would asked to be referred to a

genetic counselor and then you can get the proper testing done. Demand that

100-500 cells are tested and no less than 100 cells are analyzed. Sorry you went

through all this. Hopefully someday soon we can get these tests changed and get

a true diagnosis for people.

Let us know what happens

Kristy

Randal wrote:

Hi-

The Dr just called and said that the tests came back 'normal'. I asked the nurse

how many cells were tested. She said they analyzed 22 and karyotyped 5. Was all

of this a waste of time? Do I need to push for more to be tested and ask to be

referred to a geneticist? I am confused.

Thanks-

(mom to -11 months)

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That's what I was afraid of. I have been on pins and needles since Monday when

the nurse said he had the paperwork on his desk and would be calling. I have

been carrying my cellphone in my pocket waiting for his call and now-it was all

a waste of time and worry. This is so frustrating. I thought I would feel better

once they said everything was fine, but I know that it still may not be the

correct diagnosis. The Dr told us at the last appt that he could refer us to

Bham if we wanted, so I think we will just do that. The nurse didn't even know

what a karyotype was...

Thanks-

Jenni

Re: Re: Welcome !

Hi

Yes, it was definately a waste of time! I would asked to be referred to a

genetic counselor and then you can get the proper testing done. Demand that

100-500 cells are tested and no less than 100 cells are analyzed. Sorry you went

through all this. Hopefully someday soon we can get these tests changed and get

a true diagnosis for people.

Let us know what happens

Kristy

Randal wrote:

Hi-

The Dr just called and said that the tests came back 'normal'. I asked the

nurse how many cells were tested. She said they analyzed 22 and karyotyped 5.

Was all of this a waste of time? Do I need to push for more to be tested and ask

to be referred to a geneticist? I am confused.

Thanks-

(mom to -11 months)

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  • 2 weeks later...

Well first of all, I want to tell that my son became 10 times cuter with

his glasses ( he is farsighted and recieved them at 10 months) his eye muscles

have already started to improve 6 months later. Second, I was told by the

optomologist that the eye glasses would be designed for his face shape, and they

did some measurements at the eyeglass place, but when we recieved the glasses we

DID have problems with the nose bridge area not fitting correctly and I had to

modify this part myself to fit my son, Im not sure if it was the factories

ignorance or the eyeglass place we ordered at. So my advice would be to be FIRM

about them fitting correctly if your child needs these adjustments.

Marriah

From: Kristy Colvin <kristyimdsa (DOT) org>

Subject: Welcome !

To: mosaicds@yahoogroup s.com

Date: Sunday, September 28, 2008, 7:55 PM

Hi Everyone!

We have a new family joining us today. Here is what had to say...

My name is Wheeler..my husband and I had a baby girl on June 3, 2008 and

she was diagnosed with Mosaic Down Syndrome. Her name is Kayla Marie and she is

just the most wonderful and beautiful baby!! Kayla was diagnosed shorlty after

birth with three minor heart defects. At this time we are just watching her

heart and the doctor feels that she

wont have to have any kind of surgery. We had her eyes checked and it appears

that she is alreday near sighted and might have to have glasses in January. She

has an older brother who is 17(Kayla is my second and my

husband's first)and he just adores his baby sister. We are members of the Down

Syndrome Association of Central Ohio but I have just not

found much information about Mosaic and would like to be able to ask questions

and maybe get some help from others.

Welcome to our family ! I am so glad you have joined us! Congratulations

on your new baby! We are coming to Ohio for our 2009 Research & Awareness

conference this coming July! Hopefully we will all get to meet you and your

family then! Please feel free to ask any questions you have here. We will all be

very happy to share our experiences with you. And, feel free to share any

concerns and joys you have with Kayla. We are here for you and your family and

will always be here to help you.

Kristy

Mom to Arron 26, 23, Tim 22 MDS, Stevan 21 and Garrett 12

Kristy Colvin

IMDSA President

~~~~~~~~~~~~ ~~~~~~~~~ ~~~~~~~~~ ~~~~~~~~~ ~~~~~~~

International Mosaic Down Syndrome Association

PH:

Toll Free: 1-888-MDS-LINK

http://www.imdsa. org

http://www.mosaicmo ments.today. com

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Good for you , Im happy to see teachers taking an interest into learning all

they can about their students that experience dissabilities. This makes me feel

good and confident for when my son reaches school age that there are teachers

like you! Any question in this group, and you are sure to find at least one

wonderful answer or peice of advice!

Marriah, Gideons mom (16 months)

Subject: Welcome !

To: mosaicds

Date: Sunday, September 28, 2008, 1:55 PM

Hi Everyone

We have a new teacher joining us today. Here is what had to say...

I teach for Richmond Public Schools in a MR Adaptive Class. I have

students with autism, mental retardation, (in past with down syndrome),

one with apraxia, and possible mosaic.

Welcome to our family ! I am so glad you have joined us! We have quite a few

teachers and other professionals here, and it is always a great thing when we

have others joining us! Please feel free to ask any questions you may have. We

will all be happy to share our experiences with you!

Kristy

Mom to Arron 26, 23, Tim 22 MDS, Stevan 21 and Garrett 12

Kristy Colvin

IMDSA President

~~~~~~~~~~~~ ~~~~~~~~~ ~~~~~~~~~ ~~~~~~~~~ ~~~~~~~

International Mosaic Down Syndrome Association

PH:

Toll Free: 1-888-MDS-LINK

http://www.imdsa. org

http://www.mosaicmo ments.today. com

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Hi Everyone

We have a new family joining us today! Here is what had to say...

I am a mother of four children. My two year old son is going for genetic

testing because mosaic down syndrome is suspected.

Thank you in advance,

Montgomery

Welcome to our family ! I am so glad you joined us! Please tell us all

about your son. How old is he? Why is it suspected that he has MDS? When is your

appointment for the genetic testing?

Please feel free to ask any questions you may have. We will all be very happy

to share our experiences with you!

Kristy

Mom to Arron 26, 23, Tim 22 MDS, Stevan 21 and Garrett 12

Kristy Colvin

IMDSA President

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

International Mosaic Down Syndrome Association

PH:

Toll Free: 1-888-MDS-LINK

http://www.imdsa.org

http://www.mosaicmoments.today.com

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