New Findings on Toxic Mold 2008

[Guest guest]

New Findings on Toxic Mold 2008

http://luur.lub.lu.se/luur?func=downloadFile & fileOId=1265711

Bloom, a, Mycotoxins in Indoor Environments: Determination

using Mass Spectrometry. Doctoral Thesis 2008

This study in context:

In the mid 80s and 90s, mold problems indoors came in focus as

several disease outbreaks were detected.

However, based on number of spores found in indoor environments,

mycotoxin levels were not considered likely to pose a health threat.

This thesis project was prompted mainly by two sets of published

studies. One set showed that not only spores are released from mold-

contaminated building materials but also much smaller fungal

fragments (0.3-20 & #956;m, Górny et al 2002, Kildesø et al 2003).

These small fragments were found to be released in up to 320-514

times higher numbers than spores, share common antigens with spores

(Górny et al 2002), and demonstrate a 230-250 fold higher

respiratory deposition than spores in adults and an additional 4-5

times higher deposition in infants (Cho et al 2005). These fungal

particles (diameter < 1 & #956;m) may contain mycotoxins (Brasel et al

2005).

Thus, our exposure to mold and mycotoxins in water-damaged building

may be much higher than suggested in previous estimations based

merely on spore concentrations (Bush et al 2005, Kelman et al

2004). - These data clearly show that mycotoxins even at very low

concentrations may cause immunomodulation.

CONCLUSIONS (2 0f 4, see below)

• Molds in water-damaged indoor environments, in both sub-tropic and

tempered climatic zones, produce mycotoxins regularly. Mycotoxins

were found in settled dust on surfaces above floor level indicating

that mycotoxins from mold-contaminated building materials can become

airborne and inhalable.

• Mycotoxin production or prevalence does not seem to correlate to

microscopy findings, CFU counts, or PCR results for fungi. There is

a potential correlation between fungal biomass and mycotoxin

production.

- 59 - (Bloom, 2008) (Italics and highlighting by SMH for emphasis)

https://www.schoolmoldhelp.org/content/view/1425/65/

[Guest guest]

I've been out ofsorts for some time... and I decided to go through some old

posts... and I ran accross this one... Which begs me to ask the question: How

can we test for mycotoxin levels?

>

> New Findings on Toxic Mold 2008

>

> http://luur.lub.lu.se/luur?func=downloadFile & fileOId=1265711

>

> Bloom, a, Mycotoxins in Indoor Environments: Determination

> using Mass Spectrometry. Doctoral Thesis 2008

>

> This study in context:

>

> In the mid 80s and 90s, mold problems indoors came in focus as

> several disease outbreaks were detected.

>

> However, based on number of spores found in indoor environments,

> mycotoxin levels were not considered likely to pose a health threat.

>

> This thesis project was prompted mainly by two sets of published

> studies. One set showed that not only spores are released from mold-

> contaminated building materials but also much smaller fungal

> fragments (0.3-20 & #956;m, Górny et al 2002, Kildesø et al 2003).

>

> These small fragments were found to be released in up to 320-514

> times higher numbers than spores, share common antigens with spores

> (Górny et al 2002), and demonstrate a 230-250 fold higher

> respiratory deposition than spores in adults and an additional 4-5

> times higher deposition in infants (Cho et al 2005). These fungal

> particles (diameter < 1 & #956;m) may contain mycotoxins (Brasel et al

> 2005).

>

> Thus, our exposure to mold and mycotoxins in water-damaged building

> may be much higher than suggested in previous estimations based

> merely on spore concentrations (Bush et al 2005, Kelman et al

> 2004). - These data clearly show that mycotoxins even at very low

> concentrations may cause immunomodulation.

>

>

> CONCLUSIONS (2 0f 4, see below)

>

> • Molds in water-damaged indoor environments, in both sub-tropic and

> tempered climatic zones, produce mycotoxins regularly. Mycotoxins

> were found in settled dust on surfaces above floor level indicating

> that mycotoxins from mold-contaminated building materials can become

> airborne and inhalable.

> • Mycotoxin production or prevalence does not seem to correlate to

> microscopy findings, CFU counts, or PCR results for fungi. There is

> a potential correlation between fungal biomass and mycotoxin

> production.

> - 59 - (Bloom, 2008) (Italics and highlighting by SMH for emphasis)

>

> https://www.schoolmoldhelp.org/content/view/1425/65/

>

[Guest guest]

Bonnie,

What a Bloom did was research and the academic analysis is

very expensive. It could for the basis for a commercial method at

a more reasonable cost but that is in the future.

Dr Hooper at Realtime labs http://www.realtimelab.com/ can test

for mycotoxins in human samples and environmental samples

but the cost, as reported here, varies between $700 and $900 per

sample.

You will need several samples. There is no consensus or even

much of an idea on how much mycotoxin is needed to cause a

reaction or be of concern. Just because mycotoxin was detected

in an environmental sample does not mean it came into contact

with you. Or if it did, how much of it you were exposed to.

Mycotoxin testing, currently, can be important information but it is

not conclusive or definitive proof.

Carl Grimes

Healthy Habitats LLC

-----

>

>

>

> I've been out ofsorts for some time... and I decided to go through some old

posts... and I ran accross this

> one... Which begs me to ask the question: How can we test for mycotoxin

levels?

>

> >

> > New Findings on Toxic Mold 2008

> >

> > http://luur. lub.lu.se/luur?func=downloadFile & fileOId=1265711

> >

> > Bloom, a, Mycotoxins in Indoor Environments: Determination

> > using Mass Spectrometry. Doctoral Thesis 2008

> >

> > This study in context:

> >

> > In the mid 80s and 90s, mold problems indoors came in focus as

> > several disease outbreaks were detected.

> >

> > However, based on number of spores found in indoor environments,

> > mycotoxin levels were not considered likely to pose a health threat.

> >

> > This thesis project was prompted mainly by two sets of published

> > studies. One set showed that not only spores are released from mold-

> > contaminated building materials but also much smaller fungal

> > fragments (0.3-20 & #956;m, Górny et al 2002, Kildesø et al 2003).

> >

> > These small fragments were found to be released in up to 320-514

> > times higher numbers than spores, share common antigens with spores

> > (Górny et al 2002), and demonstrate a 230-250 fold higher

> > respiratory deposition than spores in adults and an additional 4-5

> > times higher deposition in infants (Cho et al 2005). These fungal

> > particles (diameter < 1 & #956;m) may contain mycotoxins (Brasel et al

> > 2005).

> >

> > Thus, our exposure to mold and mycotoxins in water-damaged building

> > may be much higher than suggested in previous estimations based

> > merely on spore concentrations (Bush et al 2005, Kelman et al

> > 2004). - These data clearly show that mycotoxins even at very low

> > concentrations may cause immunomodulation.

> >

> >

> > CONCLUSIONS (2 0f 4, see below)

> >

> > o Molds in water-damaged indoor environments, in both sub-tropic and

> > tempered climatic zones, produce mycotoxins regularly. Mycotoxins

> > were found in settled dust on surfaces above floor level indicating

> > that mycotoxins from mold-contaminated building materials can become

> > airborne and inhalable.

> > o Mycotoxin production or prevalence does not seem to correlate to

> > microscopy findings, CFU counts, or PCR results for fungi. There is

> > a potential correlation between fungal biomass and mycotoxin

> > production.

> > - 59 - (Bloom, 2008) (Italics and highlighting by SMH for emphasis)

> >

> > https://www. schoolmoldhelp.org/content/view/1425/65/

> >

>

>

[Guest guest]

I think testing may is an important piece of the puzzle but the main

things is how you feel. If your environment is sick then you will be and it is

different for everyone. After leaving my school and having all my blood

tested, staying at home, on and off medication and returning to school the

proof was there in the blood work and how I felt. It was amazing in just

under 15 minutes of reentry (after about 10 days out) how strange and sick I

felt!!

S

Bonnie,

What a Bloom did was research and the academic analysis is

very expensive. It could for the basis for a commercial method at

a more reasonable cost but that is in the future.

Dr Hooper at Realtime labs _http://www.realtimehttp://w_

(http://www.realtimelab.com/) can test

for mycotoxins in human samples and environmental samples

but the cost, as reported here, varies between $700 and $900 per

sample.

You will need several samples. There is no consensus or even

much of an idea on how much mycotoxin is needed to cause a

reaction or be of concern. Just because mycotoxin was detected

in an environmental sample does not mean it came into contact

with you. Or if it did, how much of it you were exposed to.

Mycotoxin testing, currently, can be important information but it is

not conclusive or definitive proof.

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