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Re: Estradiol required for immune response to pathogens

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were these middle aged mice, or teenage mice?

If the Stealth bacteria hypothesis in autoimmune disease is correct this could explain the prevalance in women as they age.

Lynn

Estradiol Is Required for a Proper Immune Response to Bacterial and Viral Pathogens in the Female Brain 1

Geneviève Soucy*, Guy Boivin, Fernand Labrie* and Serge Rivest2,*

E2 replacement therapy totally rescued the ability of the endotoxin to trigger microglial cells and these permissive effects of E2 are mediated via the estrogen receptor (ER). Indeed, ER-deficient mice exhibited an inappropriate reaction to LPS when compared with ER-deficient and wild-type mice.

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Lots of metabolic changes take place over the course of a lifetime, mice are

not people. I just read in the Ralph Moss newsletter about how well

western medicine takes care of mice.

Karima

> were these middle aged mice, or teenage mice?

>

------> No clue on that one....I'd have to pay $39 for the study to find

out.

Would it matter?

Lynn

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