Guest guest Posted April 29, 2005 Report Share Posted April 29, 2005 Dr. JM and others: Have you ever used Zinlori 75 or PepZin, which are brand names for a new zinc-carnosine chelate? Below is a post from CK2 on the supplement by a father whose opinion in judging new treatments is reliable. Thanks, Greg There is a new treatment for the gut that I believe will be very significant. Developed in Japan and marketed by Lonza under patent, it is a zinc-carnosine chelate, which is a forced molecule very different than zinc and carnosine " mixed " together. Metagenics carries it under the name Zinlori 75. There are some other brands that trademark it as PepZin. There is a laymans article at iherb.com: http://www.iherb.com/ulcers2.html#intro Here are 100 study tags from PubMed (search = polaprezinc): XXXXX http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search & DB=pubmed This message contains search results from the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Sent on Friday, 2005 Apr 29 Search polaprezinc Entrez pubmed Results Items 1 - 100 of 100 1: Isomoto H, Furusu H, Ohnita K, Wen CY, Inoue K, Kohno S. Related Articles, Books, LinkOut Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin. World J Gastroenterol. 2005 Mar 21;11(11):1629-33. PMID: 15786539 [PubMed - in process] 2: Takada T, Suzuki N, Ito-Kato E, Noguchi Y, Ito M, Maeno M, Otsuka K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on the differentiation of C2C12 cells. Life Sci. 2004 Dec 17;76(5):509-20. PMID: 15556164 [PubMed - indexed for MEDLINE] 3: Maeno M, Ito-Kato E, Suzuki N, Takada T, Takayama T, Ito K, Otsuka K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on the differentiation pathway of human periodontal ligament cells. Life Sci. 2004 Apr 2;74(20):2493-504. PMID: 15010260 [PubMed - indexed for MEDLINE] 4: Murakami K, Sato R, Okimoto T, Watanabe K, Nasu M, Fujioka T, Kodama M, Kagawa J. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Influence of anti-ulcer drugs used in Japan on the result of (13)C- urea breath test for the diagnosis of Helicobacter pylori infection. J Gastroenterol. 2003;38(10):937-41. PMID: 14614600 [PubMed - indexed for MEDLINE] 5: Eto S, Yoshinaga T, Ushijima S, Saishoji T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [A case of polaprezinc-induced pneumonitis] Nihon Kokyuki Gakkai Zasshi. 2003 Aug;41(8):561-4. Japanese. PMID: 14503344 [PubMed - indexed for MEDLINE] 6: Tameyasu T, Ohta M, Tanaka M, Ogihara K, Takahashi S, Yamanobe T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of zinc-carnosine complex on muscular function in frail distrophin-deficient (mdx) mice. Jpn J Physiol. 2002 Oct;52(5):449-56. PMID: 12533250 [PubMed - indexed for MEDLINE] 7: Odashima M, Otaka M, Jin M, Konishi N, Sato T, Kato S, Matsuhashi T, Nakamura C, Watanabe S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Induction of a 72-kDa heat-shock protein in cultured rat gastric mucosal cells and rat gastric mucosa by zinc L-carnosine. Dig Dis Sci. 2002 Dec;47(12):2799-804. PMID: 12498304 [PubMed - indexed for MEDLINE] 8: Ishihara R, Iishi H, Sakai N, Yano H, Uedo N, Narahara H, Iseki K, Mikuni T, Ishiguro S, Tatsuta M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc attenuates Helicobacter pylori-associated gastritis in Mongolian gerbils. Helicobacter. 2002 Dec;7(6):384-9. PMID: 12485126 [PubMed - indexed for MEDLINE] 9: Handa O, Yoshida N, Tanaka Y, Ueda M, Ishikawa T, Takagi T, Matsumoto N, Naito Y, Yoshikawa T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol. 2002 Nov;16(11):785-9. PMID: 12464972 [PubMed - indexed for MEDLINE] 10: Tameyasu T, Yamada M, Tanaka M, Takahashi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of zinc-carnosine chelate compound on muscle function in mdx mouse. Jpn J Physiol. 2002 Feb;52(1):111-20. PMID: 12047809 [PubMed - indexed for MEDLINE] 11: Masayuki F, Norihiko K, Keita T, Miwa I, Masayuki I, Toshihiko I, Hiromi F, Chikaaki M, Norio N. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [Efficacy and safety of polaprezinc as a preventive drug for radiation-induced stomatitis] Nippon Igaku Hoshasen Gakkai Zasshi. 2002 Mar;62(4):144-50. Japanese. PMID: 12043217 [PubMed - indexed for MEDLINE] 12: Kuwayama H, Takahashi M, Suzuki K, Suga M, Takata H, Ohara T, Koizumi K, Kiriyama Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [Polaprezinc] Nippon Rinsho. 2002 Feb;60 Suppl 2:717-20. Review. Japanese. No abstract available. PMID: 11979877 [PubMed - indexed for MEDLINE] 13: Otaka M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [Chaperon-induction therapy for peptic ulcers] Nippon Rinsho. 2002 Feb;60 Suppl 2:572-6. Review. Japanese. No abstract available. PMID: 11979849 [PubMed - indexed for MEDLINE] 14: Yoshida N, Sugimoto N, Ochiai J, Nakamura Y, Ichikawa H, Naito Y, Yoshikawa T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Role of elastase and active oxygen species in gastric mucosal injury induced by aspirin administration in Helicobacter pylori-infected Mongolian gerbils. Aliment Pharmacol Ther. 2002 Apr;16 Suppl 2:191-7. PMID: 11966541 [PubMed - indexed for MEDLINE] 15: Takagi H, Nagamine T, Abe T, Takayama H, Sato K, Otsuka T, Kakizaki S, Hashimoto Y, Matsumoto T, Kojima A, Takezawa J, Suzuki K, Sato S, Mori M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc supplementation enhances the response to interferon therapy in patients with chronic hepatitis C. J Viral Hepat. 2001 Sep;8(5):367-71. PMID: 11555194 [PubMed - indexed for MEDLINE] 16: Terano A, Hiraishi H, Shimada T, Takahashi M, Yoshiura K, Horie- Sakata K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Cell culture model for antiulcerogenic agents. Microsc Res Tech. 2001 Jun 15;53(6):389-95. PMID: 11525256 [PubMed - indexed for MEDLINE] 17: Naito Y, Yoshikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, Yoneta T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci. 2001 Apr;46(4):845-51. PMID: 11330422 [PubMed - indexed for MEDLINE] 18: Suzuki H, Mori M, Seto K, Miyazawa M, Kai A, Suematsu M, Yoneta T, Miura S, Ishii H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc attenuates the Helicobacter pylori-induced gastric mucosal leucocyte activation in Mongolian gerbils--a study using intravital videomicroscopy. Aliment Pharmacol Ther. 2001 May;15(5):715-25. PMID: 11328267 [PubMed - indexed for MEDLINE] 19: Kato S, Tanaka A, Ogawa Y, Kanatsu K, Seto K, Yoneda T, Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of polaprezinc on impaired healing of chronic gastric ulcers in adjuvant-induced arthritic rats--role of insulin-like growth factors (IGF)-1. Med Sci Monit. 2001 Jan-Feb;7(1):20-5. PMID: 11208487 [PubMed - indexed for MEDLINE] 20: Dajani EZ, Klamut MJ. Related Articles, Books, LinkOut Novel therapeutic approaches to gastric and duodenal ulcers: an update. Expert Opin Investig Drugs. 2000 Jul;9(7):1537-44. Review. PMID: 11060758 [PubMed - indexed for MEDLINE] 21: Torreggiani A, Bonora S, Fini G. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Raman and IR spectroscopic investigation of zinc(II)-carnosine complexes. Biopolymers. 2000;57(6):352-64. PMID: 11054655 [PubMed - indexed for MEDLINE] 22: Sugiyama T, Tanaka H, Kawai S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Improvement of periarticular osteoporosis in postmenopausal women with rheumatoid arthritis by beta-alanyl-L-histidinato zinc: a pilot study. J Bone Miner Metab. 2000;18(6):335-8. PMID: 11052466 [PubMed - indexed for MEDLINE] 23: Nagamine T, Takagi H, Takayama H, Kojima A, Kakizaki S, Mori M, Nakajima K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Preliminary study of combination therapy with interferon-alpha and zinc in chronic hepatitis C patients with genotype 1b. Biol Trace Elem Res. 2000 Summer;75(1-3):53-63. PMID: 11051596 [PubMed - indexed for MEDLINE] 24: Fuji Y, Matsura T, Kai M, Kawasaki H, Yamada K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Protection by polaprezinc, an anti-ulcer drug, against indomethacin- induced apoptosis in rat gastric mucosal cells. Jpn J Pharmacol. 2000 Sep;84(1):63-70. PMID: 11043455 [PubMed - indexed for MEDLINE] 25: Katayama S, Nishizawa K, Hirano M, Yamamura S, Momose Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of polaprezinc on healing of acetic acid-induced stomatitis in hamsters. J Pharm Pharm Sci. 2000 Jan-Apr;3(1):114-7. PMID: 10954680 [PubMed - indexed for MEDLINE] 26: Matsukura T, Tanaka H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Applicability of zinc complex of L-carnosine for medical use. Biochemistry (Mosc). 2000 Jul;65(7):817-23. Review. PMID: 10951100 [PubMed - indexed for MEDLINE] 27: Korolkiewicz RP, Fujita A, Seto K, Suzuki K, Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc exerts a salutary effect on impaired healing of acute gastric lesions in diabetic rats. Dig Dis Sci. 2000 Jun;45(6):1200-9. PMID: 10877238 [PubMed - indexed for MEDLINE] 28: Furuta S, Suzuki M, Toyama S, Miwa M, Sano H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Tissue distribution of polaprezinc in rats determined by the double tracer method. J Pharm Biomed Anal. 1999 Mar;19(3-4):453-61. PMID: 10704111 [PubMed - indexed for MEDLINE] 29: Suzuki H, Mori M, Seto K, Nagahashi S, Kawaguchi C, Morita H, Suzuki M, Miura S, Yoneta T, Ishii H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc, a gastroprotective agent: attenuation of monochloramine- evoked gastric DNA fragmentation. J Gastroenterol. 1999;34 Suppl 11:43-6. PMID: 10616765 [PubMed - indexed for MEDLINE] 30: Hirasaki S, Koide N, Ogawa H, Tsuji T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Benign gastric ulcer associated with Canidida infection in a healthy adult. J Gastroenterol. 1999 Dec;34(6):688-93. Review. PMID: 10588185 [PubMed - indexed for MEDLINE] 31: Shimada T, Watanabe N, Ohtsuka Y, Endoh M, Kojima K, Hiraishi H, Terano A. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc down-regulates proinflammatory cytokine-induced nuclear factor-kappaB activiation and interleukin-8 expression in gastric epithelial cells. J Pharmacol Exp Ther. 1999 Oct;291(1):345-52. PMID: 10490923 [PubMed - indexed for MEDLINE] 32: Sugawara N, Katakura M, Sugawara C. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Preventive effect of zinc compounds, polaprezinc and zinc acetate against the onset of hepatitis in Long- Cinnamon rat. Res Commun Mol Pathol Pharmacol. 1999 Feb;103(2):167-76. PMID: 10461683 [PubMed - indexed for MEDLINE] 33: Nishiwaki H, Kato S, Sugamoto S, Umeda M, Morita H, Yoneta T, Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Ulcerogenic and healing impairing actions of monochloramine in rat stomachs: effects of zinc L-carnosine, polaprezinc. J Physiol Pharmacol. 1999 Jun;50(2):183-95. PMID: 10424716 [PubMed - indexed for MEDLINE] 34: Seto K, Yoneta T, Suda H, Tamaki H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc), a novel antiulcer agent containing zinc, on cellular proliferation: role of insulin-like growth factor I. Biochem Pharmacol. 1999 Jul 15;58(2):245-50. PMID: 10423164 [PubMed - indexed for MEDLINE] 35: Kashimura H, Suzuki K, Hassan M, Ikezawa K, Sawahata T, Watanabe T, Nakahara A, Mutoh H, Tanaka N. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxycillin and clarithromycin increases the cure rate of Helicobacter pylori infection. Aliment Pharmacol Ther. 1999 Apr;13(4):483-7. PMID: 10215732 [PubMed - indexed for MEDLINE] 36: Hiraishi H, Sasai T, Oinuma T, Shimada T, Sugaya H, Terano A. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacol Ther. 1999 Feb;13(2):261-9. PMID: 10102958 [PubMed - indexed for MEDLINE] 37: Goto T, Hisiki S, Tanaka M, Siwa T, Tochikubo O, Kawaguchi Y, Yokoyama N, Komatu K, Suzuki R. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [Erosive duodenitis after eradication therapy for Helicobacter pylori] Nippon Shokakibyo Gakkai Zasshi. 1999 Jan;96(1):14-20. Japanese. PMID: 10047687 [PubMed - indexed for MEDLINE] 38: Natsuki R, Nozaki M, Fujimura H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [The inhibitory effect and the mechanism of ethanol absorption by L- carnosine zinc complex in mouse gastrointestinal tract] Nihon Arukoru Yakubutsu Igakkai Zasshi. 1998 Dec;33(6):692-702. Japanese. PMID: 10028827 [PubMed - indexed for MEDLINE] 39: Watanabe S, Wang XE, Hirose M, Kivilioto T, Osada T, Miwa H, Oide H, Kitamura T, Yoneta T, Seto K, Sato N. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Insulin-like growth factor I plays a role in gastric wound healing: evidence using a zinc derivative, polaprezinc, and an in vitro rabbit wound repair model. Aliment Pharmacol Ther. 1998 Nov;12(11):1131-8. PMID: 9845403 [PubMed - indexed for MEDLINE] 40: Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, Takahashi S, Naito Y, Kondo M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of Z-103 on TNB-induced colitis in rats. Digestion. 1997;58(5):464-8. PMID: 9383638 [PubMed - indexed for MEDLINE] 41: Kato S, Nishiwaki H, Konaka A, Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci. 1997 Oct;42(10):2156-63. PMID: 9365151 [PubMed - indexed for MEDLINE] 42: Nishiwaki H, Kato S, Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Irritant action of monochloramine in rat stomachs: effects of zinc L- carnosine (polaprezinc). Gen Pharmacol. 1997 Nov;29(5):713-8. PMID: 9347315 [PubMed - indexed for MEDLINE] 43: Yamaguchi M, Matsui T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc enhancement of 17beta-estradiol's anabolic effect in osteoblastic MC3T3-E1 cells. Calcif Tissue Int. 1997 Jun;60(6):527-32. PMID: 9164827 [PubMed - indexed for MEDLINE] 44: Ehara Y, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc stimulates protein synthesis in the femoral-metaphyseal tissues of normal and skeletally unloaded rats. Res Exp Med (Berl). 1997;196(6):363-72. PMID: 9089885 [PubMed - indexed for MEDLINE] 45: Yamaguchi I, Shibata K, Takei M, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Changes in tissue contents of zinc, copper and iron in rats and beagle dogs treated with polaprezinc. J Toxicol Sci. 1996 Aug;21(3):177-87. PMID: 8887886 [PubMed - indexed for MEDLINE] 46: Yamaguchi M, Ehara Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of essential trace metal on bone metabolism in the femoral- metaphyseal tissues of rats with skeletal unloading: comparison with zinc-chelating dipeptide. Calcif Tissue Int. 1996 Jul;59(1):27-32. PMID: 8661981 [PubMed - indexed for MEDLINE] 47: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc compounds inhibit osteoclast-like cell formation at the earlier stage of rat marrow culture but not osteoclast function. Mol Cell Biochem. 1996 May 24;158(2):171-7. PMID: 8817479 [PubMed - indexed for MEDLINE] 48: Yamaguchi M, Ehara Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc decrease and bone metabolism in the femoral-metaphyseal tissues of rats with skeletal unloading. Calcif Tissue Int. 1995 Sep;57(3):218-23. PMID: 8574940 [PubMed - indexed for MEDLINE] 49: Furuta S, Toyama S, Miwa M, Sano H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Disposition of polaprezinc (zinc L-carnosine complex) in rat gastrointestinal tract and effect of cimetidine on its adhesion to gastric tissues. J Pharm Pharmacol. 1995 Aug;47(8):632-6. PMID: 8583362 [PubMed - indexed for MEDLINE] 50: Furuta S, Toyama S, Miwa M, Itabashi T, Sano H, Yoneta T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Residence time of polaprezinc (zinc L-carnosine complex) in the rat stomach and adhesiveness to ulcerous sites. Jpn J Pharmacol. 1995 Apr;67(4):271-8. PMID: 7650862 [PubMed - indexed for MEDLINE] 51: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Differential effects of transforming growth factor-beta on osteoclast-like cell formation in mouse marrow culture: relation to the effect of zinc-chelating dipeptides. Peptides. 1995;16(8):1483-8. PMID: 8745062 [PubMed - indexed for MEDLINE] 52: Matsui T, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc modulation of insulin-like growth factor's effect in osteoblastic MC3T3-E1 cells. Peptides. 1995;16(6):1063-8. PMID: 8532589 [PubMed - indexed for MEDLINE] 53: Matsuda K, Yamaguchi I, Wada H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Toxicity of the novel anti-peptic ulcer agent polaprezinc in beagle dogs. Arzneimittelforschung. 1995 Jan;45(1):52-60. PMID: 7893270 [PubMed - indexed for MEDLINE] 54: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Inhibitory effect of zinc-chelating dipeptide on parathyroid hormone- stimulated osteoclast-like cell formation in mouse marrow cultures: involvement of calcium signaling. Peptides. 1995;16(4):629-33. PMID: 7479295 [PubMed - indexed for MEDLINE] 55: Furuta S, Toyama S, Sano H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Absorption mechanism of polaprezinc (zinc L-carnosine complex) by an everted sac method. Xenobiotica. 1994 Nov;24(11):1085-94. PMID: 7701850 [PubMed - indexed for MEDLINE] 56: Yamaguchi M, Hashizume M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on protein components in osteoblastic MC3T3-El cells: increase in osteocalcin, insulin-like growth factor-I and transforming growth factor-beta. Mol Cell Biochem. 1994 Jul 27;136(2):163-9. PMID: 7845370 [PubMed - indexed for MEDLINE] 57: Kishi S, Segawa Y, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Histomorphological confirmation of the preventive effect of beta- alanyl-L-histidinato zinc on bone loss in ovariectomized rats. Biol Pharm Bull. 1994 Jun;17(6):862-5. PMID: 7951157 [PubMed - indexed for MEDLINE] 58: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Comparison of the effect of beta-alanyl-L-histidinato zinc and its zinc-chelating ligand on bone metabolism in tissue culture. Biol Pharm Bull. 1994 Apr;17(4):522-6. PMID: 8069261 [PubMed - indexed for MEDLINE] 59: Hashizume M, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on differentiation of osteoblastic MC3T3-E1 cells: increases in alkaline phosphatase activity and protein concentration. Mol Cell Biochem. 1994 Feb 9;131(1):19-24. PMID: 8047061 [PubMed - indexed for MEDLINE] 60: Kisi S, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Stimulatory effect of beta-alanyl-L-histidinato zinc on alkaline phosphatase activity in bone tissues from elderly rats: comparison with zinc sulfate action. Biol Pharm Bull. 1994 Feb;17(2):345-7. PMID: 8205136 [PubMed - indexed for MEDLINE] 61: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of zinc-chelating dipeptide on bone metabolism in weanling rats: comparison with beta-alanyl-L-histidinato zinc-related compounds. Peptides. 1994;15(4):671-3. PMID: 7937344 [PubMed - indexed for MEDLINE] 62: Yamaguchi M, Hashizume M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of parathyroid hormone and interleukin-1 alpha in osteoblastic MC3T3-E1 cells: interaction with beta-alanyl-L- histidinato zinc. Peptides. 1994;15(4):633-6. PMID: 7937338 [PubMed - indexed for MEDLINE] 63: Yamaguchi M, Kishi S, Hashizume M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of zinc-chelating dipeptides on osteoblastic MC3T3-E1 cells: activation of aminoacyl-tRNA synthetase. Peptides. 1994;15(8):1367-71. PMID: 7700838 [PubMed - indexed for MEDLINE] 64: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Prolonged administration of beta-alanyl-L-histidinato zinc prevents bone loss in ovariectomized rats. Jpn J Pharmacol. 1993 Oct;63(2):203-7. PMID: 8283831 [PubMed - indexed for MEDLINE] 65: Segawa Y, Tsuzuike N, Itokazu Y, Tagashira E, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on bone metabolism in rats with adjuvant arthritis. Biol Pharm Bull. 1993 Jul;16(7):656-9. PMID: 8401397 [PubMed - indexed for MEDLINE] 66: Tsuzuike N, Segawa Y, Tagashira E, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Beta-alanyl-L-histidinato zinc enhances various bone-regulating factors' effects on bone alkaline phosphatase activity in tissue culture. Pharmacology. 1993 Jul;47(1):66-72. PMID: 8337234 [PubMed - indexed for MEDLINE] 67: Hashizume M, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Stimulatory effect of beta-alanyl-L-histidinato zinc on cell proliferation is dependent on protein synthesis in osteoblastic MC3T3- E1 cells. Mol Cell Biochem. 1993 May 12;122(1):59-64. PMID: 8350864 [PubMed - indexed for MEDLINE] 68: Segawa Y, Tsuzuike N, Tagashira E, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Preventive effect of beta-alanyl-L-histidinato zinc on the deterioration of bone metabolism in ovariectomized rats. Biol Pharm Bull. 1993 May;16(5):486-9. PMID: 8364496 [PubMed - indexed for MEDLINE] 69: Green OP, Deoraj P, Gopinath C, Crook D, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Toxicity of the novel anti-peptic ulcer agent catena-(S)-[mu-[Na- (3- aminopropionyl)histidinato(2-)-N1,N2,Q:N tau]-zinc in male cynomolgus monkeys. Arzneimittelforschung. 1993 May;43(5):562-9. PMID: 8329001 [PubMed - indexed for MEDLINE] 70: Seiki M, Aita H, Ueki S, Yoneta T, Takemasa T, Hori Y, Morita H, Chaki K, Tagashira E. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [Effect of Z-103 on wound healing by dermal incision in guinea pigs] Nippon Yakurigaku Zasshi. 1992 Aug;100(2):165-72. Japanese. PMID: 1385281 [PubMed - indexed for MEDLINE] 71: Ito M, Shii D, Segami T, Kojima R, Suzuki Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Preventive actions of N-(3-aminopropionyl)-L-histidinato zinc (Z- 103) through increases in the activities of oxygen-derived free radical scavenging enzymes in the gastric mucosa on ethanol-induced gastric mucosal damage in rats. Jpn J Pharmacol. 1992 Jul;59(3):267-74. PMID: 1434125 [PubMed - indexed for MEDLINE] 72: Aita H, Yoneta T, Seto K, Morita H, Hori Y, Takemasa T, Chaki K, Yamada H, Seiki M, Tagashira E. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [studies on the healing promoting action of Z-103 in chronic gastric ulcer models of rats] Nippon Yakurigaku Zasshi. 1992 May;99(5):345-52. Japanese. PMID: 1592317 [PubMed - indexed for MEDLINE] 73: Seiki M, Aita H, Mera Y, Arai K, Toyama S, Furuta S, Morita H, Hori Y, Yoneta T, Tagashira E. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [The gastric mucosal adhesiveness of Z-103 in rats with chronic ulcer] Nippon Yakurigaku Zasshi. 1992 Apr;99(4):255-63. Japanese. PMID: 1607133 [PubMed - indexed for MEDLINE] 74: Segawa Y, Tsuzuike N, Tagashira E, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Preventive effect of beta-alanyl-L-histidinato zinc on bone metabolism in rats fed on low-calcium and vitamin D-deficient diets. Res Exp Med (Berl). 1992;192(3):213-9. PMID: 1636066 [PubMed - indexed for MEDLINE] 75: Yamaguchi M, Segawa Y, Shimokawa N, Tsuzuike N, Tagashira E. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Inhibitory effect of beta-alanyl-L-histidinato zinc on bone resorption in tissue culture. Pharmacology. 1992;45(5):292-300. PMID: 1465476 [PubMed - indexed for MEDLINE] 76: Segawa Y, Tsuzuike N, Itokazu Y, Tagashira E, Yamaguchi M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut beta-Alanyl-L-histidinato zinc prevents hydrocortisone-induced disorder of bone metabolism in rats. Res Exp Med (Berl). 1992;192(5):317-22. PMID: 1439196 [PubMed - indexed for MEDLINE] 77: Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinato zinc. Biochim Biophys Acta. 1991 Nov 14;1115(1):15-22. PMID: 1659910 [PubMed - indexed for MEDLINE] 78: Shibata K, Matsuda K, Ohta T, Sasaki Y, Sutou S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Mutagenicity studies on catena-(S)-[mu-[N alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] Arzneimittelforschung. 1991 Oct;41(10):1053-7. PMID: 1799383 [PubMed - indexed for MEDLINE] 79: Shibata K, Matsuda K, Wada H, Aruga F, Yamada Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Antigenicity studies on catena-(S)-[mu-[N alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] Arzneimittelforschung. 1991 Oct;41(10):1048-52. PMID: 1799382 [PubMed - indexed for MEDLINE] 80: Matsuda K, Nishi N, Hiramatsu Y, Shimizu M, Ohta T, Kato M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Reproductive and developmental toxicity studies on catena-(S)-[mu- [N alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] Arzneimittelforschung. 1991 Oct;41(10):1042-8. PMID: 1799381 [PubMed - indexed for MEDLINE] 81: Matsuda K, Mera Y, Wada H, Aruga H, Saik Y, Taniguchi Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Repeated dose toxicity studies on catena-(S)-[mu-[N alpha-(3- aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] in rats. Arzneimittelforschung. 1991 Oct;41(10):1036-41. PMID: 1799380 [PubMed - indexed for MEDLINE] 82: Matsuda K, Shibata K, Morikami H, Kato T, Aruga F. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Single dose toxicity study on catena-(S)-[mu-[N alpha-(3- aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] in mice and rats. Arzneimittelforschung. 1991 Oct;41(10):1033-5. PMID: 1799379 [PubMed - indexed for MEDLINE] 83: Furuta S, Toyama S, Miwa M, Ikeda Y, Sano H, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 4th communication: disposition of zinc and amino acids in rats, dogs and monkeys. Arzneimittelforschung. 1991 Sep;41(9):992-5. PMID: 1796930 [PubMed - indexed for MEDLINE] 84: Toyama S, Furuta S, Miwa M, Suzuki M, Sano H, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Study on the metabolic fate of catena-(S)-[mu-N alpha-(3- aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 3rd communication: transfer into fetus and milk in rats. Arzneimittelforschung. 1991 Sep;41(9):984-91. PMID: 1796929 [PubMed - indexed for MEDLINE] 85: Toyama S, Furuta S, Miwa M, Suzuki M, Sano H, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 2nd communication: absorption, distribution, metabolism and excretion after repeated administration to rats. Arzneimittelforschung. 1991 Sep;41(9):976-83. PMID: 1796928 [PubMed - indexed for MEDLINE] 86: Sano H, Furuta S, Toyama S, Miwa M, Ikeda Y, Suzuki M, Sato H, Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 1st communication: absorption, distribution, metabolism and excretion after single administration to rats. Arzneimittelforschung. 1991 Sep;41(9):965-75. PMID: 1796927 [PubMed - indexed for MEDLINE] 87: Cho CH, Luk CT, Ogle CW. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut The membrane-stabilizing action of zinc carnosine (Z-103) in stress- induced gastric ulceration in rats. Life Sci. 1991;49(23):PL189-94. PMID: 1943472 [PubMed - indexed for MEDLINE] 88: Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Yasuda M, Ueda S, Oyamada H, Kondo M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury induced by ischemia- reperfusion in rats. Free Radic Res Commun. 1991;14(4):289-96. PMID: 1874458 [PubMed - indexed for MEDLINE] 89: Yamaguchi M, Miwa H. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Stimulatory effect of beta-alanyl-L-histidinato zinc on bone formation in tissue culture. Pharmacology. 1991;42(4):230-40. PMID: 1852783 [PubMed - indexed for MEDLINE] 90: Yamaguchi M, Ohtaki J. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of beta-alanyl-L-histidinato zinc on osteoblastic MC3T3-E1 cells: increases in alkaline phosphatase and proliferation. Pharmacology. 1991;43(4):225-32. PMID: 1771175 [PubMed - indexed for MEDLINE] 91: Matsukura T, Takahashi T, Nishimura Y, Ohtani T, Sawada M, Shibata K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Characterization of crystalline L-carnosine Zn(II) complex (Z-103), a novel anti-gastric ulcer agent: tautomeric change of imidazole moiety upon complexation. Chem Pharm Bull (Tokyo). 1990 Nov;38(11):3140-6. PMID: 2085900 [PubMed - indexed for MEDLINE] 92: Seiki M, Ueki S, Tanaka Y, Soeda M, Hori Y, Aita H, Yoneta T, Morita H, Tagashira E, Okabe S. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut [studies on anti-ulcer effects of a new compound, zinc L-carnosine (Z-103)] Nippon Yakurigaku Zasshi. 1990 May;95(5):257-69. Japanese. PMID: 2113032 [PubMed - indexed for MEDLINE] 93: Ito M, Tanaka T, Suzuki Y. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of N-(3-aminopropionyl)-L-histidinato zinc (Z-103) on healing and hydrocortisone-induced relapse of acetic acid ulcers in rats with limited food-intake-time. Jpn J Pharmacol. 1990 Apr;52(4):513-21. PMID: 2342223 [PubMed - indexed for MEDLINE] 94: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut A new zinc compound, beta-alanyl-L-histidinato zinc, stimulates bone growth in weanling rats. Res Exp Med (Berl). 1990;190(2):105-10. PMID: 2349394 [PubMed - indexed for MEDLINE] 95: Naito Y, Yoshikawa T, Tanigawa T, Yoneta T, Ueda S, Oyamada H, Takemura T, Sugino S, Kondo M. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Zinc-carnosine chelate compound (Z-103) attenuates acute gastric mucosal injury induced by ischemia-reperfusion in rats. Adv Exp Med Biol. 1990;264:411-4. No abstract available. PMID: 2244521 [PubMed - indexed for MEDLINE] 96: Yamaguchi M, Ozaki K, Hoshi T. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Beta-alanyl-L-histidinato zinc prevents skeletal unloading-induced disorder of bone metabolism in rats. Res Exp Med (Berl). 1990;190(4):289-94. PMID: 2218077 [PubMed - indexed for MEDLINE] 97: Tanigawa T, Yoshikawa T, Naito Y, Yoneta T, Ueda S, Oyamada H, Takemura T, Morita Y, Tainaka K, Yoshida N, et al. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Antioxidative action of zinc-carnosine compound Z-103. Adv Exp Med Biol. 1990;264:223-8. No abstract available. PMID: 2173871 [PubMed - indexed for MEDLINE] 98: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of the new zinc compound beta-alanyl-L-histidinato zinc on bone metabolism in elderly rats. Pharmacology. 1990;41(6):345-9. PMID: 2096395 [PubMed - indexed for MEDLINE] 99: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Beta-alanyl-L-histidinato zinc prevents the toxic effect of aluminium on bone metabolism in weanling rats. Pharmacology. 1990;41(6):338-44. PMID: 2096394 [PubMed - indexed for MEDLINE] 100: Ueki S, Seiki M, Yoneta T, Omata T, Hori Y, Ishikawa M, Tagashira E. Related Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut Effect of Z-103 on compound 48/80-induced gastric lesions in rats. Scand J Gastroenterol Suppl. 1989;162:202-5. PMID: 2480637 [PubMed - indexed for MEDLINE] --- End forwarded message --- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2005 Report Share Posted April 29, 2005 Sorry, this is a new one on me. I'll look into it, thanks! Dr. JM Zinc-carnosine complex > Dr. JM and others: > > Have you ever used Zinlori 75 or PepZin, which are brand names for a > new zinc-carnosine chelate? Below is a post from CK2 on the > supplement by a father whose opinion in judging new treatments is > reliable. > > Thanks, > Greg > > > There is a new treatment for the gut that I believe will be very > significant. Developed in Japan and marketed by Lonza under patent, > it is a zinc-carnosine chelate, which is a forced molecule very > different than zinc and carnosine " mixed " together. Metagenics > carries it under the name Zinlori 75. There are some other brands > that trademark it as PepZin. There is a laymans article at > iherb.com: > > http://www.iherb.com/ulcers2.html#intro > > Here are 100 study tags from PubMed (search = > polaprezinc): > > XXXXX > > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search & DB=pubmed > > This message contains search results from the National Center for > Biotechnology Information (NCBI) at the U.S. National Library of > Medicine (NLM). > Do not reply directly to this message. > > Sender's message: > > Sent on Friday, 2005 Apr 29 > Search polaprezinc > > > Entrez pubmed Results > Items 1 - 100 of 100 > 1: Isomoto H, Furusu H, Ohnita K, Wen CY, Inoue K, Kohno S. Related > Articles, Books, LinkOut > Sofalcone, a mucoprotective agent, increases the cure rate of > Helicobacter pylori infection when combined with rabeprazole, > amoxicillin and clarithromycin. > World J Gastroenterol. 2005 Mar 21;11(11):1629-33. > PMID: 15786539 [PubMed - in process] > 2: Takada T, Suzuki N, Ito-Kato E, Noguchi Y, Ito M, Maeno M, > Otsuka > K. Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Effect of beta-alanyl-L-histidinato zinc on the differentiation of > C2C12 cells. > Life Sci. 2004 Dec 17;76(5):509-20. > PMID: 15556164 [PubMed - indexed for MEDLINE] > 3: Maeno M, Ito-Kato E, Suzuki N, Takada T, Takayama T, Ito K, > Otsuka K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Effect of beta-alanyl-L-histidinato zinc on the differentiation > pathway of human periodontal ligament cells. > Life Sci. 2004 Apr 2;74(20):2493-504. > PMID: 15010260 [PubMed - indexed for MEDLINE] > 4: Murakami K, Sato R, Okimoto T, Watanabe K, Nasu M, Fujioka T, > Kodama M, Kagawa J. Related Articles, Compound via MeSH, Substance > via MeSH, Books, LinkOut > Influence of anti-ulcer drugs used in Japan on the result of (13)C- > urea breath test for the diagnosis of Helicobacter pylori infection. > J Gastroenterol. 2003;38(10):937-41. > PMID: 14614600 [PubMed - indexed for MEDLINE] > 5: Eto S, Yoshinaga T, Ushijima S, Saishoji T. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > [A case of polaprezinc-induced pneumonitis] > Nihon Kokyuki Gakkai Zasshi. 2003 Aug;41(8):561-4. Japanese. > PMID: 14503344 [PubMed - indexed for MEDLINE] > 6: Tameyasu T, Ohta M, Tanaka M, Ogihara K, Takahashi S, Yamanobe > T. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Effect of zinc-carnosine complex on muscular function in frail > distrophin-deficient (mdx) mice. > Jpn J Physiol. 2002 Oct;52(5):449-56. > PMID: 12533250 [PubMed - indexed for MEDLINE] > 7: Odashima M, Otaka M, Jin M, Konishi N, Sato T, Kato S, > Matsuhashi > T, Nakamura C, Watanabe S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Induction of a 72-kDa heat-shock protein in cultured rat gastric > mucosal cells and rat gastric mucosa by zinc L-carnosine. > Dig Dis Sci. 2002 Dec;47(12):2799-804. > PMID: 12498304 [PubMed - indexed for MEDLINE] > 8: Ishihara R, Iishi H, Sakai N, Yano H, Uedo N, Narahara H, Iseki > K, Mikuni T, Ishiguro S, Tatsuta M. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Polaprezinc attenuates Helicobacter pylori-associated gastritis in > Mongolian gerbils. > Helicobacter. 2002 Dec;7(6):384-9. > PMID: 12485126 [PubMed - indexed for MEDLINE] > 9: Handa O, Yoshida N, Tanaka Y, Ueda M, Ishikawa T, Takagi T, > Matsumoto N, Naito Y, Yoshikawa T. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Inhibitory effect of polaprezinc on the inflammatory response to > Helicobacter pylori. > Can J Gastroenterol. 2002 Nov;16(11):785-9. > PMID: 12464972 [PubMed - indexed for MEDLINE] > 10: Tameyasu T, Yamada M, Tanaka M, Takahashi S. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Effect of zinc-carnosine chelate compound on muscle function in mdx > mouse. > Jpn J Physiol. 2002 Feb;52(1):111-20. > PMID: 12047809 [PubMed - indexed for MEDLINE] > 11: Masayuki F, Norihiko K, Keita T, Miwa I, Masayuki I, Toshihiko > I, Hiromi F, Chikaaki M, Norio N. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > [Efficacy and safety of polaprezinc as a preventive drug for > radiation-induced stomatitis] > Nippon Igaku Hoshasen Gakkai Zasshi. 2002 Mar;62(4):144-50. > Japanese. > PMID: 12043217 [PubMed - indexed for MEDLINE] > 12: Kuwayama H, Takahashi M, Suzuki K, Suga M, Takata H, Ohara T, > Koizumi K, Kiriyama Y. Related Articles, Compound via MeSH, > Substance > via MeSH, Books, LinkOut > [Polaprezinc] > Nippon Rinsho. 2002 Feb;60 Suppl 2:717-20. Review. Japanese. No > abstract available. > PMID: 11979877 [PubMed - indexed for MEDLINE] > 13: Otaka M. Related Articles, Compound via MeSH, Substance via > MeSH, Books, LinkOut > [Chaperon-induction therapy for peptic ulcers] > Nippon Rinsho. 2002 Feb;60 Suppl 2:572-6. Review. Japanese. No > abstract available. > PMID: 11979849 [PubMed - indexed for MEDLINE] > 14: Yoshida N, Sugimoto N, Ochiai J, Nakamura Y, Ichikawa H, Naito > Y, Yoshikawa T. Related Articles, Compound via MeSH, Substance via > MeSH, Books, LinkOut > Role of elastase and active oxygen species in gastric mucosal > injury > induced by aspirin administration in Helicobacter pylori-infected > Mongolian gerbils. > Aliment Pharmacol Ther. 2002 Apr;16 Suppl 2:191-7. > PMID: 11966541 [PubMed - indexed for MEDLINE] > 15: Takagi H, Nagamine T, Abe T, Takayama H, Sato K, Otsuka T, > Kakizaki S, Hashimoto Y, Matsumoto T, Kojima A, Takezawa J, Suzuki > K, > Sato S, Mori M. Related Articles, Compound via MeSH, Substance via > MeSH, Books, LinkOut > Zinc supplementation enhances the response to interferon therapy in > patients with chronic hepatitis C. > J Viral Hepat. 2001 Sep;8(5):367-71. > PMID: 11555194 [PubMed - indexed for MEDLINE] > 16: Terano A, Hiraishi H, Shimada T, Takahashi M, Yoshiura K, Horie- > Sakata K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Cell culture model for antiulcerogenic agents. > Microsc Res Tech. 2001 Jun 15;53(6):389-95. > PMID: 11525256 [PubMed - indexed for MEDLINE] > 17: Naito Y, Yoshikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, > Yoneta T. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Effects of polaprezinc on lipid peroxidation, neutrophil > accumulation, and TNF-alpha expression in rats with aspirin-induced > gastric mucosal injury. > Dig Dis Sci. 2001 Apr;46(4):845-51. > PMID: 11330422 [PubMed - indexed for MEDLINE] > 18: Suzuki H, Mori M, Seto K, Miyazawa M, Kai A, Suematsu M, Yoneta > T, Miura S, Ishii H. Related Articles, Compound via MeSH, Substance > via MeSH, Books, LinkOut > Polaprezinc attenuates the Helicobacter pylori-induced gastric > mucosal leucocyte activation in Mongolian gerbils--a study using > intravital videomicroscopy. > Aliment Pharmacol Ther. 2001 May;15(5):715-25. > PMID: 11328267 [PubMed - indexed for MEDLINE] > 19: Kato S, Tanaka A, Ogawa Y, Kanatsu K, Seto K, Yoneda T, > Takeuchi > K. Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Effect of polaprezinc on impaired healing of chronic gastric ulcers > in adjuvant-induced arthritic rats--role of insulin-like growth > factors (IGF)-1. > Med Sci Monit. 2001 Jan-Feb;7(1):20-5. > PMID: 11208487 [PubMed - indexed for MEDLINE] > 20: Dajani EZ, Klamut MJ. Related Articles, Books, LinkOut > Novel therapeutic approaches to gastric and duodenal ulcers: an > update. > Expert Opin Investig Drugs. 2000 Jul;9(7):1537-44. Review. > PMID: 11060758 [PubMed - indexed for MEDLINE] > 21: Torreggiani A, Bonora S, Fini G. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Raman and IR spectroscopic investigation of zinc(II)-carnosine > complexes. > Biopolymers. 2000;57(6):352-64. > PMID: 11054655 [PubMed - indexed for MEDLINE] > 22: Sugiyama T, Tanaka H, Kawai S. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Improvement of periarticular osteoporosis in postmenopausal women > with rheumatoid arthritis by beta-alanyl-L-histidinato zinc: a pilot > study. > J Bone Miner Metab. 2000;18(6):335-8. > PMID: 11052466 [PubMed - indexed for MEDLINE] > 23: Nagamine T, Takagi H, Takayama H, Kojima A, Kakizaki S, Mori M, > Nakajima K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Preliminary study of combination therapy with interferon-alpha and > zinc in chronic hepatitis C patients with genotype 1b. > Biol Trace Elem Res. 2000 Summer;75(1-3):53-63. > PMID: 11051596 [PubMed - indexed for MEDLINE] > 24: Fuji Y, Matsura T, Kai M, Kawasaki H, Yamada K. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Protection by polaprezinc, an anti-ulcer drug, against indomethacin- > induced apoptosis in rat gastric mucosal cells. > Jpn J Pharmacol. 2000 Sep;84(1):63-70. > PMID: 11043455 [PubMed - indexed for MEDLINE] > 25: Katayama S, Nishizawa K, Hirano M, Yamamura S, Momose Y. > Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Effect of polaprezinc on healing of acetic acid-induced stomatitis > in hamsters. > J Pharm Pharm Sci. 2000 Jan-Apr;3(1):114-7. > PMID: 10954680 [PubMed - indexed for MEDLINE] > 26: Matsukura T, Tanaka H. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Applicability of zinc complex of L-carnosine for medical use. > Biochemistry (Mosc). 2000 Jul;65(7):817-23. Review. > PMID: 10951100 [PubMed - indexed for MEDLINE] > 27: Korolkiewicz RP, Fujita A, Seto K, Suzuki K, Takeuchi K. > Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Polaprezinc exerts a salutary effect on impaired healing of acute > gastric lesions in diabetic rats. > Dig Dis Sci. 2000 Jun;45(6):1200-9. > PMID: 10877238 [PubMed - indexed for MEDLINE] > 28: Furuta S, Suzuki M, Toyama S, Miwa M, Sano H. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Tissue distribution of polaprezinc in rats determined by the double > tracer method. > J Pharm Biomed Anal. 1999 Mar;19(3-4):453-61. > PMID: 10704111 [PubMed - indexed for MEDLINE] > 29: Suzuki H, Mori M, Seto K, Nagahashi S, Kawaguchi C, Morita H, > Suzuki M, Miura S, Yoneta T, Ishii H. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Polaprezinc, a gastroprotective agent: attenuation of > monochloramine- > evoked gastric DNA fragmentation. > J Gastroenterol. 1999;34 Suppl 11:43-6. > PMID: 10616765 [PubMed - indexed for MEDLINE] > 30: Hirasaki S, Koide N, Ogawa H, Tsuji T. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Benign gastric ulcer associated with Canidida infection in a > healthy > adult. > J Gastroenterol. 1999 Dec;34(6):688-93. Review. > PMID: 10588185 [PubMed - indexed for MEDLINE] > 31: Shimada T, Watanabe N, Ohtsuka Y, Endoh M, Kojima K, Hiraishi > H, > Terano A. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Polaprezinc down-regulates proinflammatory cytokine-induced nuclear > factor-kappaB activiation and interleukin-8 expression in gastric > epithelial cells. > J Pharmacol Exp Ther. 1999 Oct;291(1):345-52. > PMID: 10490923 [PubMed - indexed for MEDLINE] > 32: Sugawara N, Katakura M, Sugawara C. Related Articles, Compound > via MeSH, Substance via MeSH, Books, LinkOut > Preventive effect of zinc compounds, polaprezinc and zinc acetate > against the onset of hepatitis in Long- Cinnamon rat. > Res Commun Mol Pathol Pharmacol. 1999 Feb;103(2):167-76. > PMID: 10461683 [PubMed - indexed for MEDLINE] > 33: Nishiwaki H, Kato S, Sugamoto S, Umeda M, Morita H, Yoneta T, > Takeuchi K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Ulcerogenic and healing impairing actions of monochloramine in rat > stomachs: effects of zinc L-carnosine, polaprezinc. > J Physiol Pharmacol. 1999 Jun;50(2):183-95. > PMID: 10424716 [PubMed - indexed for MEDLINE] > 34: Seto K, Yoneta T, Suda H, Tamaki H. Related Articles, Compound > via MeSH, Substance via MeSH, Books, LinkOut > Effect of polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc), a > novel antiulcer agent containing zinc, on cellular proliferation: > role of insulin-like growth factor I. > Biochem Pharmacol. 1999 Jul 15;58(2):245-50. > PMID: 10423164 [PubMed - indexed for MEDLINE] > 35: Kashimura H, Suzuki K, Hassan M, Ikezawa K, Sawahata T, > Watanabe > T, Nakahara A, Mutoh H, Tanaka N. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Polaprezinc, a mucosal protective agent, in combination with > lansoprazole, amoxycillin and clarithromycin increases the cure rate > of Helicobacter pylori infection. > Aliment Pharmacol Ther. 1999 Apr;13(4):483-7. > PMID: 10215732 [PubMed - indexed for MEDLINE] > 36: Hiraishi H, Sasai T, Oinuma T, Shimada T, Sugaya H, Terano A. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Polaprezinc protects gastric mucosal cells from noxious agents > through antioxidant properties in vitro. > Aliment Pharmacol Ther. 1999 Feb;13(2):261-9. > PMID: 10102958 [PubMed - indexed for MEDLINE] > 37: Goto T, Hisiki S, Tanaka M, Siwa T, Tochikubo O, Kawaguchi Y, > Yokoyama N, Komatu K, Suzuki R. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > [Erosive duodenitis after eradication therapy for Helicobacter > pylori] > Nippon Shokakibyo Gakkai Zasshi. 1999 Jan;96(1):14-20. Japanese. > PMID: 10047687 [PubMed - indexed for MEDLINE] > 38: Natsuki R, Nozaki M, Fujimura H. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > [The inhibitory effect and the mechanism of ethanol absorption by L- > carnosine zinc complex in mouse gastrointestinal tract] > Nihon Arukoru Yakubutsu Igakkai Zasshi. 1998 Dec;33(6):692-702. > Japanese. > PMID: 10028827 [PubMed - indexed for MEDLINE] > 39: Watanabe S, Wang XE, Hirose M, Kivilioto T, Osada T, Miwa H, > Oide H, Kitamura T, Yoneta T, Seto K, Sato N. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Insulin-like growth factor I plays a role in gastric wound healing: > evidence using a zinc derivative, polaprezinc, and an in vitro > rabbit > wound repair model. > Aliment Pharmacol Ther. 1998 Nov;12(11):1131-8. > PMID: 9845403 [PubMed - indexed for MEDLINE] > 40: Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, > Takahashi S, Naito Y, Kondo M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of Z-103 on TNB-induced colitis in rats. > Digestion. 1997;58(5):464-8. > PMID: 9383638 [PubMed - indexed for MEDLINE] > 41: Kato S, Nishiwaki H, Konaka A, Takeuchi K. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Mucosal ulcerogenic action of monochloramine in rat stomachs: > effects of polaprezinc and sucralfate. > Dig Dis Sci. 1997 Oct;42(10):2156-63. > PMID: 9365151 [PubMed - indexed for MEDLINE] > 42: Nishiwaki H, Kato S, Takeuchi K. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Irritant action of monochloramine in rat stomachs: effects of zinc > L- > carnosine (polaprezinc). > Gen Pharmacol. 1997 Nov;29(5):713-8. > PMID: 9347315 [PubMed - indexed for MEDLINE] > 43: Yamaguchi M, Matsui T. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc enhancement of 17beta-estradiol's anabolic effect in > osteoblastic MC3T3-E1 cells. > Calcif Tissue Int. 1997 Jun;60(6):527-32. > PMID: 9164827 [PubMed - indexed for MEDLINE] > 44: Ehara Y, Yamaguchi M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc stimulates protein synthesis in the femoral-metaphyseal > tissues > of normal and skeletally unloaded rats. > Res Exp Med (Berl). 1997;196(6):363-72. > PMID: 9089885 [PubMed - indexed for MEDLINE] > 45: Yamaguchi I, Shibata K, Takei M, Matsuda K. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Changes in tissue contents of zinc, copper and iron in rats and > beagle dogs treated with polaprezinc. > J Toxicol Sci. 1996 Aug;21(3):177-87. > PMID: 8887886 [PubMed - indexed for MEDLINE] > 46: Yamaguchi M, Ehara Y. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of essential trace metal on bone metabolism in the femoral- > metaphyseal tissues of rats with skeletal unloading: comparison with > zinc-chelating dipeptide. > Calcif Tissue Int. 1996 Jul;59(1):27-32. > PMID: 8661981 [PubMed - indexed for MEDLINE] > 47: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc compounds inhibit osteoclast-like cell formation at the > earlier > stage of rat marrow culture but not osteoclast function. > Mol Cell Biochem. 1996 May 24;158(2):171-7. > PMID: 8817479 [PubMed - indexed for MEDLINE] > 48: Yamaguchi M, Ehara Y. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc decrease and bone metabolism in the femoral-metaphyseal > tissues > of rats with skeletal unloading. > Calcif Tissue Int. 1995 Sep;57(3):218-23. > PMID: 8574940 [PubMed - indexed for MEDLINE] > 49: Furuta S, Toyama S, Miwa M, Sano H. Related Articles, Compound > via MeSH, Substance via MeSH, Books, LinkOut > Disposition of polaprezinc (zinc L-carnosine complex) in rat > gastrointestinal tract and effect of cimetidine on its adhesion to > gastric tissues. > J Pharm Pharmacol. 1995 Aug;47(8):632-6. > PMID: 8583362 [PubMed - indexed for MEDLINE] > 50: Furuta S, Toyama S, Miwa M, Itabashi T, Sano H, Yoneta T. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Residence time of polaprezinc (zinc L-carnosine complex) in the rat > stomach and adhesiveness to ulcerous sites. > Jpn J Pharmacol. 1995 Apr;67(4):271-8. > PMID: 7650862 [PubMed - indexed for MEDLINE] > 51: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Differential effects of transforming growth factor-beta on > osteoclast-like cell formation in mouse marrow culture: relation to > the effect of zinc-chelating dipeptides. > Peptides. 1995;16(8):1483-8. > PMID: 8745062 [PubMed - indexed for MEDLINE] > 52: Matsui T, Yamaguchi M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc modulation of insulin-like growth factor's effect in > osteoblastic MC3T3-E1 cells. > Peptides. 1995;16(6):1063-8. > PMID: 8532589 [PubMed - indexed for MEDLINE] > 53: Matsuda K, Yamaguchi I, Wada H. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Toxicity of the novel anti-peptic ulcer agent polaprezinc in beagle > dogs. > Arzneimittelforschung. 1995 Jan;45(1):52-60. > PMID: 7893270 [PubMed - indexed for MEDLINE] > 54: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Inhibitory effect of zinc-chelating dipeptide on parathyroid > hormone- > stimulated osteoclast-like cell formation in mouse marrow cultures: > involvement of calcium signaling. > Peptides. 1995;16(4):629-33. > PMID: 7479295 [PubMed - indexed for MEDLINE] > 55: Furuta S, Toyama S, Sano H. Related Articles, Compound via > MeSH, > Substance via MeSH, Books, LinkOut > Absorption mechanism of polaprezinc (zinc L-carnosine complex) by > an > everted sac method. > Xenobiotica. 1994 Nov;24(11):1085-94. > PMID: 7701850 [PubMed - indexed for MEDLINE] > 56: Yamaguchi M, Hashizume M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of beta-alanyl-L-histidinato zinc on protein components in > osteoblastic MC3T3-El cells: increase in osteocalcin, insulin-like > growth factor-I and transforming growth factor-beta. > Mol Cell Biochem. 1994 Jul 27;136(2):163-9. > PMID: 7845370 [PubMed - indexed for MEDLINE] > 57: Kishi S, Segawa Y, Yamaguchi M. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Histomorphological confirmation of the preventive effect of beta- > alanyl-L-histidinato zinc on bone loss in ovariectomized rats. > Biol Pharm Bull. 1994 Jun;17(6):862-5. > PMID: 7951157 [PubMed - indexed for MEDLINE] > 58: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Comparison of the effect of beta-alanyl-L-histidinato zinc and its > zinc-chelating ligand on bone metabolism in tissue culture. > Biol Pharm Bull. 1994 Apr;17(4):522-6. > PMID: 8069261 [PubMed - indexed for MEDLINE] > 59: Hashizume M, Yamaguchi M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of beta-alanyl-L-histidinato zinc on differentiation of > osteoblastic MC3T3-E1 cells: increases in alkaline phosphatase > activity and protein concentration. > Mol Cell Biochem. 1994 Feb 9;131(1):19-24. > PMID: 8047061 [PubMed - indexed for MEDLINE] > 60: Kisi S, Yamaguchi M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Stimulatory effect of beta-alanyl-L-histidinato zinc on alkaline > phosphatase activity in bone tissues from elderly rats: comparison > with zinc sulfate action. > Biol Pharm Bull. 1994 Feb;17(2):345-7. > PMID: 8205136 [PubMed - indexed for MEDLINE] > 61: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of zinc-chelating dipeptide on bone metabolism in weanling > rats: comparison with beta-alanyl-L-histidinato zinc-related > compounds. > Peptides. 1994;15(4):671-3. > PMID: 7937344 [PubMed - indexed for MEDLINE] > 62: Yamaguchi M, Hashizume M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of parathyroid hormone and interleukin-1 alpha in > osteoblastic MC3T3-E1 cells: interaction with beta-alanyl-L- > histidinato zinc. > Peptides. 1994;15(4):633-6. > PMID: 7937338 [PubMed - indexed for MEDLINE] > 63: Yamaguchi M, Kishi S, Hashizume M. Related Articles, Compound > via MeSH, Substance via MeSH, Books, LinkOut > Effect of zinc-chelating dipeptides on osteoblastic MC3T3-E1 cells: > activation of aminoacyl-tRNA synthetase. > Peptides. 1994;15(8):1367-71. > PMID: 7700838 [PubMed - indexed for MEDLINE] > 64: Yamaguchi M, Kishi S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Prolonged administration of beta-alanyl-L-histidinato zinc prevents > bone loss in ovariectomized rats. > Jpn J Pharmacol. 1993 Oct;63(2):203-7. > PMID: 8283831 [PubMed - indexed for MEDLINE] > 65: Segawa Y, Tsuzuike N, Itokazu Y, Tagashira E, Yamaguchi M. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Effect of beta-alanyl-L-histidinato zinc on bone metabolism in rats > with adjuvant arthritis. > Biol Pharm Bull. 1993 Jul;16(7):656-9. > PMID: 8401397 [PubMed - indexed for MEDLINE] > 66: Tsuzuike N, Segawa Y, Tagashira E, Yamaguchi M. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Beta-alanyl-L-histidinato zinc enhances various bone-regulating > factors' effects on bone alkaline phosphatase activity in tissue > culture. > Pharmacology. 1993 Jul;47(1):66-72. > PMID: 8337234 [PubMed - indexed for MEDLINE] > 67: Hashizume M, Yamaguchi M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Stimulatory effect of beta-alanyl-L-histidinato zinc on cell > proliferation is dependent on protein synthesis in osteoblastic > MC3T3- > E1 cells. > Mol Cell Biochem. 1993 May 12;122(1):59-64. > PMID: 8350864 [PubMed - indexed for MEDLINE] > 68: Segawa Y, Tsuzuike N, Tagashira E, Yamaguchi M. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Preventive effect of beta-alanyl-L-histidinato zinc on the > deterioration of bone metabolism in ovariectomized rats. > Biol Pharm Bull. 1993 May;16(5):486-9. > PMID: 8364496 [PubMed - indexed for MEDLINE] > 69: Green OP, Deoraj P, Gopinath C, Crook D, Matsuda K. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Toxicity of the novel anti-peptic ulcer agent catena-(S)-[mu-[Na- > (3- > aminopropionyl)histidinato(2-)-N1,N2,Q:N tau]-zinc in male > cynomolgus > monkeys. > Arzneimittelforschung. 1993 May;43(5):562-9. > PMID: 8329001 [PubMed - indexed for MEDLINE] > 70: Seiki M, Aita H, Ueki S, Yoneta T, Takemasa T, Hori Y, Morita > H, > Chaki K, Tagashira E. Related Articles, Compound via MeSH, Substance > via MeSH, Books, LinkOut > [Effect of Z-103 on wound healing by dermal incision in guinea pigs] > Nippon Yakurigaku Zasshi. 1992 Aug;100(2):165-72. Japanese. > PMID: 1385281 [PubMed - indexed for MEDLINE] > 71: Ito M, Shii D, Segami T, Kojima R, Suzuki Y. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Preventive actions of N-(3-aminopropionyl)-L-histidinato zinc (Z- > 103) through increases in the activities of oxygen-derived free > radical scavenging enzymes in the gastric mucosa on ethanol-induced > gastric mucosal damage in rats. > Jpn J Pharmacol. 1992 Jul;59(3):267-74. > PMID: 1434125 [PubMed - indexed for MEDLINE] > 72: Aita H, Yoneta T, Seto K, Morita H, Hori Y, Takemasa T, Chaki > K, > Yamada H, Seiki M, Tagashira E. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > [studies on the healing promoting action of Z-103 in chronic > gastric > ulcer models of rats] > Nippon Yakurigaku Zasshi. 1992 May;99(5):345-52. Japanese. > PMID: 1592317 [PubMed - indexed for MEDLINE] > 73: Seiki M, Aita H, Mera Y, Arai K, Toyama S, Furuta S, Morita H, > Hori Y, Yoneta T, Tagashira E. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > [The gastric mucosal adhesiveness of Z-103 in rats with chronic > ulcer] > Nippon Yakurigaku Zasshi. 1992 Apr;99(4):255-63. Japanese. > PMID: 1607133 [PubMed - indexed for MEDLINE] > 74: Segawa Y, Tsuzuike N, Tagashira E, Yamaguchi M. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Preventive effect of beta-alanyl-L-histidinato zinc on bone > metabolism in rats fed on low-calcium and vitamin D-deficient diets. > Res Exp Med (Berl). 1992;192(3):213-9. > PMID: 1636066 [PubMed - indexed for MEDLINE] > 75: Yamaguchi M, Segawa Y, Shimokawa N, Tsuzuike N, Tagashira E. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Inhibitory effect of beta-alanyl-L-histidinato zinc on bone > resorption in tissue culture. > Pharmacology. 1992;45(5):292-300. > PMID: 1465476 [PubMed - indexed for MEDLINE] > 76: Segawa Y, Tsuzuike N, Itokazu Y, Tagashira E, Yamaguchi M. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > beta-Alanyl-L-histidinato zinc prevents hydrocortisone-induced > disorder of bone metabolism in rats. > Res Exp Med (Berl). 1992;192(5):317-22. > PMID: 1439196 [PubMed - indexed for MEDLINE] > 77: Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > The antioxidant properties of a novel zinc-carnosine chelate > compound, N-(3-aminopropionyl)-L-histidinato zinc. > Biochim Biophys Acta. 1991 Nov 14;1115(1):15-22. > PMID: 1659910 [PubMed - indexed for MEDLINE] > 78: Shibata K, Matsuda K, Ohta T, Sasaki Y, Sutou S. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Mutagenicity studies on catena-(S)-[mu-[N alpha-(3-aminopropionyl) > histidinato(2-)-N1,N2,O:N tau]-zinc] > Arzneimittelforschung. 1991 Oct;41(10):1053-7. > PMID: 1799383 [PubMed - indexed for MEDLINE] > 79: Shibata K, Matsuda K, Wada H, Aruga F, Yamada Y. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Antigenicity studies on catena-(S)-[mu-[N alpha-(3-aminopropionyl) > histidinato(2-)-N1,N2,O:N tau]-zinc] > Arzneimittelforschung. 1991 Oct;41(10):1048-52. > PMID: 1799382 [PubMed - indexed for MEDLINE] > 80: Matsuda K, Nishi N, Hiramatsu Y, Shimizu M, Ohta T, Kato M. > Related Articles, Compound via MeSH, Substance via MeSH, Books, > LinkOut > Reproductive and developmental toxicity studies on catena-(S)-[mu- > [N > alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] > Arzneimittelforschung. 1991 Oct;41(10):1042-8. > PMID: 1799381 [PubMed - indexed for MEDLINE] > 81: Matsuda K, Mera Y, Wada H, Aruga H, Saik Y, Taniguchi Y. > Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Repeated dose toxicity studies on catena-(S)-[mu-[N alpha-(3- > aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] in rats. > Arzneimittelforschung. 1991 Oct;41(10):1036-41. > PMID: 1799380 [PubMed - indexed for MEDLINE] > 82: Matsuda K, Shibata K, Morikami H, Kato T, Aruga F. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Single dose toxicity study on catena-(S)-[mu-[N alpha-(3- > aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] in mice and > rats. > Arzneimittelforschung. 1991 Oct;41(10):1033-5. > PMID: 1799379 [PubMed - indexed for MEDLINE] > 83: Furuta S, Toyama S, Miwa M, Ikeda Y, Sano H, Matsuda K. Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- > aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 4th > communication: disposition of zinc and amino acids in rats, dogs and > monkeys. > Arzneimittelforschung. 1991 Sep;41(9):992-5. > PMID: 1796930 [PubMed - indexed for MEDLINE] > 84: Toyama S, Furuta S, Miwa M, Suzuki M, Sano H, Matsuda K. > Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Study on the metabolic fate of catena-(S)-[mu-N alpha-(3- > aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 3rd > communication: transfer into fetus and milk in rats. > Arzneimittelforschung. 1991 Sep;41(9):984-91. > PMID: 1796929 [PubMed - indexed for MEDLINE] > 85: Toyama S, Furuta S, Miwa M, Suzuki M, Sano H, Matsuda K. > Related > Articles, Compound via MeSH, Substance via MeSH, Books, LinkOut > Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- > aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 2nd > communication: absorption, distribution, metabolism and excretion > after repeated administration to rats. > Arzneimittelforschung. 1991 Sep;41(9):976-83. > PMID: 1796928 [PubMed - indexed for MEDLINE] > 86: Sano H, Furuta S, Toyama S, Miwa M, Ikeda Y, Suzuki M, Sato H, > Matsuda K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3- > aminopropionyl)histidinato(2-)-N1,N2,O:N tau]-zinc]. 1st > communication: absorption, distribution, metabolism and excretion > after single administration to rats. > Arzneimittelforschung. 1991 Sep;41(9):965-75. > PMID: 1796927 [PubMed - indexed for MEDLINE] > 87: Cho CH, Luk CT, Ogle CW. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > The membrane-stabilizing action of zinc carnosine (Z-103) in stress- > induced gastric ulceration in rats. > Life Sci. 1991;49(23):PL189-94. > PMID: 1943472 [PubMed - indexed for MEDLINE] > 88: Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Yasuda M, Ueda S, > Oyamada H, Kondo M. Related Articles, Compound via MeSH, Substance > via MeSH, Books, LinkOut > Effect of zinc-carnosine chelate compound (Z-103), a novel > antioxidant, on acute gastric mucosal injury induced by ischemia- > reperfusion in rats. > Free Radic Res Commun. 1991;14(4):289-96. > PMID: 1874458 [PubMed - indexed for MEDLINE] > 89: Yamaguchi M, Miwa H. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Stimulatory effect of beta-alanyl-L-histidinato zinc on bone > formation in tissue culture. > Pharmacology. 1991;42(4):230-40. > PMID: 1852783 [PubMed - indexed for MEDLINE] > 90: Yamaguchi M, Ohtaki J. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of beta-alanyl-L-histidinato zinc on osteoblastic MC3T3-E1 > cells: increases in alkaline phosphatase and proliferation. > Pharmacology. 1991;43(4):225-32. > PMID: 1771175 [PubMed - indexed for MEDLINE] > 91: Matsukura T, Takahashi T, Nishimura Y, Ohtani T, Sawada M, > Shibata K. Related Articles, Compound via MeSH, Substance via MeSH, > Books, LinkOut > Characterization of crystalline L-carnosine Zn(II) complex (Z-103), > a novel anti-gastric ulcer agent: tautomeric change of imidazole > moiety upon complexation. > Chem Pharm Bull (Tokyo). 1990 Nov;38(11):3140-6. > PMID: 2085900 [PubMed - indexed for MEDLINE] > 92: Seiki M, Ueki S, Tanaka Y, Soeda M, Hori Y, Aita H, Yoneta T, > Morita H, Tagashira E, Okabe S. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > [studies on anti-ulcer effects of a new compound, zinc L-carnosine > (Z-103)] > Nippon Yakurigaku Zasshi. 1990 May;95(5):257-69. Japanese. > PMID: 2113032 [PubMed - indexed for MEDLINE] > 93: Ito M, Tanaka T, Suzuki Y. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of N-(3-aminopropionyl)-L-histidinato zinc (Z-103) on > healing > and hydrocortisone-induced relapse of acetic acid ulcers in rats > with > limited food-intake-time. > Jpn J Pharmacol. 1990 Apr;52(4):513-21. > PMID: 2342223 [PubMed - indexed for MEDLINE] > 94: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > A new zinc compound, beta-alanyl-L-histidinato zinc, stimulates > bone > growth in weanling rats. > Res Exp Med (Berl). 1990;190(2):105-10. > PMID: 2349394 [PubMed - indexed for MEDLINE] > 95: Naito Y, Yoshikawa T, Tanigawa T, Yoneta T, Ueda S, Oyamada H, > Takemura T, Sugino S, Kondo M. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Zinc-carnosine chelate compound (Z-103) attenuates acute gastric > mucosal injury induced by ischemia-reperfusion in rats. > Adv Exp Med Biol. 1990;264:411-4. No abstract available. > PMID: 2244521 [PubMed - indexed for MEDLINE] > 96: Yamaguchi M, Ozaki K, Hoshi T. Related Articles, Compound via > MeSH, Substance via MeSH, Books, LinkOut > Beta-alanyl-L-histidinato zinc prevents skeletal unloading-induced > disorder of bone metabolism in rats. > Res Exp Med (Berl). 1990;190(4):289-94. > PMID: 2218077 [PubMed - indexed for MEDLINE] > 97: Tanigawa T, Yoshikawa T, Naito Y, Yoneta T, Ueda S, Oyamada H, > Takemura T, Morita Y, Tainaka K, Yoshida N, et al. Related Articles, > Compound via MeSH, Substance via MeSH, Books, LinkOut > Antioxidative action of zinc-carnosine compound Z-103. > Adv Exp Med Biol. 1990;264:223-8. No abstract available. > PMID: 2173871 [PubMed - indexed for MEDLINE] > 98: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Effect of the new zinc compound beta-alanyl-L-histidinato zinc on > bone metabolism in elderly rats. > Pharmacology. 1990;41(6):345-9. > PMID: 2096395 [PubMed - indexed for MEDLINE] > 99: Yamaguchi M, Ozaki K. Related Articles, Compound via MeSH, > Substance via MeSH, Books, LinkOut > Beta-alanyl-L-histidinato zinc prevents the toxic effect of > aluminium on bone metabolism in weanling rats. > Pharmacology. 1990;41(6):338-44. > PMID: 2096394 [PubMed - indexed for MEDLINE] > 100: Ueki S, Seiki M, Yoneta T, Omata T, Hori Y, Ishikawa M, > Tagashira E. Related Articles, Compound via MeSH, Substance via > MeSH, > Books, LinkOut > Effect of Z-103 on compound 48/80-induced gastric lesions in rats. > Scand J Gastroenterol Suppl. 1989;162:202-5. > PMID: 2480637 [PubMed - indexed for MEDLINE] > --- End forwarded message --- > > > > > > > > > Many frequently asked questions and answers can be found at <http://forums.autism-rxguidebook.com/default.aspx> > > Quote Link to comment Share on other sites More sharing options...
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