Immunosuppressants for PSC

[Guest guest]

I'm sure one of the reasons your doctor is against trying these drugs,

in your case, is that they have not been tested for this indication.

Therefore you would be an experiment of one. These drugs are not without

adverse effects, significant ones. There are indicated for diseases that

are devastating or killers (RA and MS). So he may have your best

interests in mind here.

What I was implying in my earlier post was that folks like are

being treated with CellCept and in other areas, folks like Dr. Kaplan

are using Methotrexate in the tx of PSC. No one knows if this is

effective. Until someone or a company decides to try these anti-TNF

drugs in a formal trial for PSC, I'm not sure any doctor will take this

risk. Or ask a patient to take the risk. You may eventually convince

your doctor that you are willing to take the risk. But beware, there are

significant adverse effects, including anaphylaxis.

Aubrey