Guest guest Posted December 27, 1999 Report Share Posted December 27, 1999 Just a few notes (again) about the drugs. Dr. Tony Bass my hepatologist at UC San Francisco mentioned that qualitatively speaking his Urso patients are doing slightly better than his Actigall patients. This is not a study, only what he has noticed in a hundred patients. I believe it is the same drug (urso dioxilic acid sp?) but under different names. However, only Urso is FDA approved. Perhaps someone has additional info on this. Dr. Bass knows Dr. Chapman from their time together in the UK. Dr. Chapman is doing the large dosage Urso/Actigall trials. Result of his previous studies, as well as those done by others indicate YOU MUST BE TAKE AT LEAST 20mg/DAY PER KILOGRAM OF YOUR BODY WEIGHT FOR URSO/ACTIGALL TO BE EFFECTIVE. A kilogram is 2.2 lbs. So for me, since I weigh 170 lbs: 170 divided by 2.2 multiplied by 20 mg= 1,545 mg a day. So I take a bit more at 2,000 mg/day spread out over 3 meals. In my case, in 9 months all my LFTs with the exception of Bilyrubin are now within a normal range. Everyone's results will vary depending on how the schelorising is occuring and where, and how your chemistry handles the prescription. Again in my case, I had to slowly increase the dosage up to my present amount to avoid gastro probs. Dr. Chapman is studying doses of 30 mg/day per kilogram of body weight. It is too early for any results at these higher dosage levels. I will keep the group informed, as I see Dr. Bass in 6 months, and always ask him about Chapman. Dirk PSC 1985 Quote Link to comment Share on other sites More sharing options...
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