Changing status of XMRV/HGRV research -NGS

[Guest guest]

http://bit.ly/szQUhQ

THE Cheney CLINIC

Changing status of XMRV / HGRV research

December 5th, 2011,

published in Public Relations

There is still no consensus in either direction for the

existence or non-existence of XMRV associated with CFS

cases.

Studies out of Europe (Belgium and Germany) and the US

(Cornell) as well as elsewhere which are separate from

WPI, FDA and NCI are demonstrating evidence that cannot

be due to a mouse contaminant for XMRV association with

CFS.

The strongest supportive study to date was reported by Dr.

Strayer out of Hemispherex Inc, (Philadephia, PA) at

IACFS/ME in Ottawa and showed that 7/8 CFS cases and

2/17 controls were positive for XMRV using Next Generation

Sequencing (NGS) technology available at Roche Labs in

Germany.

NGS is not susceptible to mouse contamination and

demonstrates that XMRV is in fact integrated into human

DNA which means it is a human virus.

The Science (Lombardi et al, 2009) study still stands as the

best evidence that this virus is transmissible from cell to

cell and the studies out of WPI and Belgium demonstrate

an immune response (antibodies) to XMRV and a cytokine

profile (WPI) that suggests it is pathologic.

I expect that Next Generation Sequencing or NGS, which

does not have the flaws of PCR technology in evaluating a

poorly understood human virus(es), will be the best way

forward to a consensus as to the question of association of

CFS with XMRV/HGRV.

This preliminary report out of Germany using NGS as well as

human immune response data supports the association of

XMRV with CFS, despite the flaws exposed in the current

primary PCR technology used to define this scientific

debate which appears very messy and excessively

bio-political to date.

[Guest guest]

Hi Jan,

Do you know if the research currently being done by Lipkin, Mikovitz and others

will be using Next Generation Sequencing or NGS? Do you know of any other

research being done using Next Generation Sequencing or NGS?

Peace, Love and Harmony,

Bev

>

>

> http://bit.ly/szQUhQ

>

> THE Cheney CLINIC

>

> Changing status of XMRV / HGRV research

>

> December 5th, 2011,

>

> published in Public Relations

>

> There is still no consensus in either direction for the

> existence or non-existence of XMRV associated with CFS

> cases.

>

> Studies out of Europe (Belgium and Germany) and the US

> (Cornell) as well as elsewhere which are separate from

> WPI, FDA and NCI are demonstrating evidence that cannot

> be due to a mouse contaminant for XMRV association with

> CFS.

>

> The strongest supportive study to date was reported by Dr.

> Strayer out of Hemispherex Inc, (Philadephia, PA) at

> IACFS/ME in Ottawa and showed that 7/8 CFS cases and

> 2/17 controls were positive for XMRV using Next Generation

> Sequencing (NGS) technology available at Roche Labs in

> Germany.

>

> NGS is not susceptible to mouse contamination and

> demonstrates that XMRV is in fact integrated into human

> DNA which means it is a human virus.

>

> The Science (Lombardi et al, 2009) study still stands as the

> best evidence that this virus is transmissible from cell to

> cell and the studies out of WPI and Belgium demonstrate

> an immune response (antibodies) to XMRV and a cytokine

> profile (WPI) that suggests it is pathologic.

>