Guest guest Posted February 21, 2004 Report Share Posted February 21, 2004 My Rheumy just started me on Enbrel last week (I have had a total of 2 shots). One day after the second injection, started feeling changes in my mood. At first I attributed it to PMS but it kept getting worse (far worse than I have ever had with PMS). For the last few days I have felt depressed (at times pretty severely). Now, I am on Zoloft for anxiety problems and have had depression before, but it's rare and non-existent all together with the Zoloft. I have been fine lately until starting the Enbrel. I never put the two together until I mentioned it to my GP and she said that one of the (rarer) side effects of Enbrel is depression. Does anyone have any experience with this? I don't want to have arthritis pain but I certainly don't want to be severely depressed. I am due to inject myself today but wonder if I should just stop for now. I have called my rheumy but he has yet to call me back (well, his nurse...he never calls). Thanks, SC Quote Link to comment Share on other sites More sharing options...
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