Guest guest Posted February 9, 2004 Report Share Posted February 9, 2004 Can someone explain the progression of DMARDS medication? I have gone thru all the usual oral meds and either they are ineffective (cox-2 inhibitors) or I am allergic. The only one that really helped my pain was Placquenil, but developed an allergic reaction. Same with Quinacrine, Mobic and others. I then started Methotrexate weekly injections (avoided the oral route because of GI problems) and initially had some relief. After a couple months the pain crept back again, then my liver functions tests were off so the dose was decreased slightly. LFTs are still off so now rheumy added leukovorin. I don't feel any better after 2 weeks and am wondering what the next step may be. If I don't get some relief I will be considering fusion of some finger joints. This scares me because I would lose more time off work and concerned about loss of function/ future employment issues. I'd appreciate any ideas and info on fusion of finger joints Joanne Quote Link to comment Share on other sites More sharing options...
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