Re: Vitamin B12 Supplementation May Benefit Patients with Polyneurop...

[Guest guest]

Another DUH!

Amazing - all this research to document what RDs have known for many years,

if they paid attention to the s/s of B vitamin deficiency!

Neuropathy (tingling of extremities) is a classic sign of B-12 (and other B

vitamins) deficiency that I've been addressing for at least 15 years! This

research is NOT new but nice to have updated stuff to show our docs when we

recommend B-12 testing/supplementation with neuropathy patients.

hhc.sagepub.com/cgi/reprint/9/1/29.pdf

for the full journal article I wrote, documenting research showing

neuropathies as signs of thiamin, niacin and B-12 deficiencies back in 1996

Jan Patenaude, RD, CLT

Specializing in IBS, Migraine, Fibromyalgia (now) - Did a lot of psych and

LTC in the past.

In a message dated 1/16/2008 6:43:32 A.M. Mountain Standard Time,

fivestar@... writes:

Colleagues, the following is FYI and does not necessarily reflect my own

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Vitamin B12 Supplementation May Benefit Patients with Polyneuropathy

_http://www.vitasearhttp://wwwhttp://www.vit_

(http://www.vitasearch.com/CP/weeklyupdates/)

Reference: " Vitamin B12 and Methylmalonic Acid Levels in Patients

Presenting with Polyneuropathy,Presenting with Polyneuropathy,<WBR> "

Nerve, 2007; 36(4): 532-535. (Address: RA Nardin, Beth Israel Deaconess

Medical Center, Department of Neurology, 330 Brookline Avenue, E-CC 810,

Boston, MA 02215, USA).

Summary: In a retrospective cohort study involving 581 patients with

polyneuropathy, supplementation with vitamin B12 was found to bring

about significant subjective improvement in symptoms. Of the 581

subjects, 4% were found to have definite vitamin B12 deficiency (defined

as 240 pg/ml or less), and 32% were found to have possible vitamin B12

deficiency (defined as > 240 pg/ml and methylmalonic acid level > 243

nmol/L). Supplementation with vitamin B12 brought about subjective

improvement in symptoms in 87% of subjects with definite deficiency, and

43% of subjects with possible deficiency. The authors conclude,

" Possible vitamin B12 deficiency, defined as an elevated MMA level, is a

common finding in patients with polyneuropathy and treatment of these

patients with vitamin B12 may lead to clinical improvement.p

Jan Patenaude, RD

Consultant, Speaker, Writer

Director of Medical Nutrition

Signet Diagnostic Corporation

(Mountain Time)

(toll free)

Fax:

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Mediator Release Testing and LEAP Diet Protocol for Irritable Bowel

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