Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 Nice to see this! And, we must not forget that IF a client is Vit D deficient, we should check for the " cause " - one of which is celiac disease - which is also a cause of osteopenia even with no GI involvement. Jan Patenaude, RD, CLT In a message dated 1/16/2008 6:41:09 A.M. Mountain Standard Time, fivestar@... writes: Colleagues, the following is FYI and does not necessarily reflect my own opinion. I have no further knowledge of the topic. If you do not wish to receive these posts, set your email filter to filter out any messages coming from @nutritionucanlivewcoming from @nutritionucanlivew<WBR>ith anything coming from me. --------------------------------------------------------- Long-term 1,25(OH)2 vitamin D therapy increases bone mineral density in osteopenic women. Comparison with the effect of plain vitamin D. Zofkova I, Hill M. Institute of Endocrinology, Prague, Czech Republic. _izofko@..._ (mailto:izofko@...) . BACKGROUND AND AIMS: Although the bone protective effect of vitamin D has been studied intensively, the usefulness of 1,25(OH)2D3 in treating osteoporosis is still questionable. The aim of the present prospective study was to evaluate the effect of a standard pharmacological dose of 1,25(OH)2D3 in postmenopausal unsubstituted women. METHODS: Our study group comprised 52 post-menopausal women with low normal or osteopenic values of bone mineral density (BMD). Thirty-two of them were treated with 1,25(OH)2D3 for 3 years. In parallel, another group of women was treated with cholecalciferol (n=20). Vitamin D adequacy before administration of 1,25(OH)2D3 and compliance with treatment were checked by serum PTH levels, which were assessed at the start and three times in the course of treatment. RESULTS: Increase in BMD at the spine at the end of the 1st, 2nd and 3rd years of treatment with 1,25(OH)2D3 (expressed as a percentage of the value before treatment) was higher, but did not significantly differ from the effect of plain vitamin D. A significant increase in BMD at the hip at the end of the 3rd (but not the 1st and 2nd) year of treatment with 1,25(OH)2D3 was found (p<0.05, compared with the effect of plain vitamin D). The protective effect of cholecalciferol was found only on spine but not hip BMD. CONCLUSION: The study supports the hypothesis that long-term administration of 1,25(OH)2D3 is effective in treating low bone mass in postmenopausal women. PMID: 18172369 [PubMed - in process] -- ne Holden, MS, RD < _fivestar@nutritionufivestar@nutfiv_ (mailto:fivestar@...) > " Ask the Parkinson Dietitian " _http://www.parkinsohttp:/_ (http://www.parkinson.org/) " Eat well, stay well with Parkinson's disease " " Parkinson's disease: Guidelines for Medical Nutrition Therapy " _http://www.nutritiohttp://www.nuthttp_ (http://www.nutritionucanlivewith.com/) Jan Patenaude, RD, CLT Consultant, Speaker, Author Director of Medical Nutrition Signet Diagnostic Corporation (Mountain Time) (toll free) Fax: DineRight4@... Mediator Release Testing and LEAP Diet Protocol for Irritable Bowel Syndrome, Migraine, Fibromyalgia and more, caused by food sensitivity IMPORTANT - This e-mail message is intended only for the use of the individual or entity to which it is addressed, and may contain information that is privileged, confidential and exempt from disclosure under applicable law. If you have received this message in error, you are hereby notified that we do not consent to any reading, dissemination, distribution or copying of this e-mail message. If you have received this communication in error, please notify the sender immediately by e-mail and telephone ( toll free) and destroy the transmitted information. E-mail transmission cannot be guaranteed to be secure or error-free as information could be intercepted, corrupted, lost, destroyed, arrive late, incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message, which arise as a result of e-mail transmission. **************Start the year off right. Easy ways to stay in shape. http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489 Quote Link to comment Share on other sites More sharing options...
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