Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 I have friend who has a brother with Pancreatic Cancer. My friend wants to fight for his brother and refuses to accept the proposed outcome. I would like to help him with some diet tips. I am doing my research but in the interim, if any of you specialize in Pancreatic cancer and can offer diet tips, it would be greatly appreciated. The main concern is severe weight loss after chemo, of course related to decreased PO as a result of stomach ulcers. Any references, tips, etc. much appreciated. Thanks for your time and professional consideration. Sincerely, Brown, MS, RD No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 Hi - I'm an oncology dietitian and have had quite a few pancreatic ca pts past few months. I'm not sure if the pt has had surgery (whipple) or chemo/radiation yet. If the pt is just starting out with tx and feeling good, I would rec increasing po intake with increased pro/carb and mod fat intake. If po intake is poor and wt loss has begun - rec any high cal foods tolerated As far as nutritional supplements - I would start with Resurgex. I would make sure the pt is on a proton-pump inhibitor (like protonix or nexium) to reduce stomach acid. Also, there is a good hand out on the oncology listserve about pancreatic enzymes. Pts with pancreatic ca often have problems with malabsorption (fat) and benefit from pancreatic enzymes. Pancrealipase MT is a good one to try. Symptoms of malabsorption include foul smelling, oily stool, and GI complaints. Obviously, each pt is different and there response to treatment and outcomes are very individual, including susceptibility for cachexia. I have seen some research recommending Omega 3 supplements to help decrease wt loss in pancreatic pts. The evidence based recs say that fish oil does not have strong evidence to support wt gain, but from anecdotal experience with pts, I believe that it helps. I would rec 1000-2000mg EPA in the Omega 3 supplement. Carlsons is a brand often preferred by pts. I hope this helps. If you can't get the pancreatic enzyme handout - I could email it to you. Baker, MS,RD Brown wrote: I have friend who has a brother with Pancreatic Cancer. My friend wants to fight for his brother and refuses to accept the proposed outcome. I would like to help him with some diet tips. I am doing my research but in the interim, if any of you specialize in Pancreatic cancer and can offer diet tips, it would be greatly appreciated. The main concern is severe weight loss after chemo, of course related to decreased PO as a result of stomach ulcers. Any references, tips, etc. much appreciated. Thanks for your time and professional consideration. Sincerely, Brown, MS, RD No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 There's EASY ACCESS on-line info on the PanCan website: http://www.pancan.org/ Dianne Kiyomoto, RD ================================================= --- Baker wrote: > Hi - > I'm an oncology dietitian and have had quite a > few pancreatic ca pts past few months. I'm not sure > if the pt has had surgery (whipple) or > chemo/radiation yet. If the pt is just starting out > with tx and feeling good, I would rec increasing po > intake with increased pro/carb and mod fat intake. > If po intake is poor and wt loss has begun - rec any > high cal foods tolerated > As far as nutritional supplements - I would start > with Resurgex. I would make sure the pt is on a > proton-pump inhibitor (like protonix or nexium) to > reduce stomach acid. Also, there is a good hand out > on the oncology listserve about pancreatic enzymes. > Pts with pancreatic ca often have problems with > malabsorption (fat) and benefit from pancreatic > enzymes. Pancrealipase MT is a good one to try. > Symptoms of malabsorption include foul smelling, > oily stool, and GI complaints. Obviously, each pt is > different and there response to treatment and > outcomes are very individual, including > susceptibility for cachexia. I have seen some > research recommending Omega 3 supplements to help > decrease wt loss in pancreatic pts. The evidence > based recs say that fish oil does not have strong > evidence to support wt gain, but from anecdotal > experience with pts, I believe that it helps. I > would rec 1000-2000mg EPA in the Omega 3 supplement. > Carlsons is a brand often preferred by pts. > I hope this helps. > If you can't get the pancreatic enzyme handout - I > could email it to you. > > Baker, MS,RD > > Brown wrote: > I have friend who has a brother with > Pancreatic Cancer. > > My friend wants to fight for his brother and refuses > to accept the proposed > outcome. > > I would like to help him with some diet tips. I am > doing my research but in > the interim, if any of you specialize in Pancreatic > cancer and can offer > diet tips, it would be greatly appreciated. > > The main concern is severe weight loss after chemo, > of course related to > decreased PO as a result of stomach ulcers. > > Any references, tips, etc. much appreciated. > > Thanks for your time and professional consideration. > Sincerely, > Brown, MS, RD > > No virus found in this outgoing message. > Checked by AVG Free Edition. > Version: 7.5.516 / Virus Database: 269.17.13/1207 - > Release Date: 1/2/2008 > 11:29 AM > > > [Non-text portions of this message have been > removed] > > > > > > > --------------------------------- > Never miss a thing. Make Yahoo your homepage. > > [Non-text portions of this message have been > removed] > > NOTICE: This confidential message/attachment contains information intended for a specific individual(s) and purpose. Any inappropriate use, distribution or copying is strictly prohibited. If received in error, notify the sender and immediately delete the message, please. ________________________________________________________________________________\ ____ Looking for last minute shopping deals? Find them fast with Yahoo! Search. http://tools.search.yahoo.com/newsearch/category.php?category=shopping Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2008 Report Share Posted January 5, 2008 Hello beth, First, thanks ! I didn't know omega 3 PUFA can help decrease wt loss in pancreatic pts (anti-cachexia effect). I knew omega 3 PUFA are very useful during radio/chemotherapy as they seems to increase the cytotoxicity of several anticancer drugs. The mechanism is probably mediated through lipid peroxidation because the antitumour effect of n-3 PUFAs is shared with the n-6 PUFA, arachidonic acid, and abolished by antioxidants like vitamin E. Radio/chemotherapy kills cancer cells with oxidative stress (reactive oxygen species) among other mechanisms. Furthermore, omega 3 PUFA downregulate eicosanoid synthesis from cyclooxygenase II and reduce angiogenesis, inflammation and metastasis induction. Have a nice day and courage for your brother's friend. -- Frederic Courtois, RD, PhD Re: Pancreatic Cancer & Diet > Hi - > I'm an oncology dietitian and have had quite a few pancreatic ca pts > past few months. I'm not sure if the pt has had surgery (whipple) or > chemo/radiation yet. If the pt is just starting out with tx and feeling > good, I would rec increasing po intake with increased pro/carb and mod fat > intake. If po intake is poor and wt loss has begun - rec any high cal > foods tolerated > As far as nutritional supplements - I would start with Resurgex. I would > make sure the pt is on a proton-pump inhibitor (like protonix or nexium) > to reduce stomach acid. Also, there is a good hand out on the oncology > listserve about pancreatic enzymes. Pts with pancreatic ca often have > problems with malabsorption (fat) and benefit from pancreatic enzymes. > Pancrealipase MT is a good one to try. Symptoms of malabsorption include > foul smelling, oily stool, and GI complaints. Obviously, each pt is > different and there response to treatment and outcomes are very > individual, including susceptibility for cachexia. I have seen some > research recommending Omega 3 supplements to help decrease wt loss in > pancreatic pts. The evidence based recs say that fish oil does not have > strong evidence to support wt gain, but from anecdotal experience with > pts, I believe that it helps. I would rec 1000-2000mg EPA in the Omega 3 > supplement. Carlsons is a brand often preferred by pts. > I hope this helps. > If you can't get the pancreatic enzyme handout - I could email it to you. > > Baker, MS,RD > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2008 Report Share Posted January 5, 2008 Hello beth, First, thanks ! I didn't know omega 3 PUFA can help decrease wt loss in pancreatic pts (anti-cachexia effect). I knew omega 3 PUFA are very useful during radio/chemotherapy as they seems to increase the cytotoxicity of several anticancer drugs. The mechanism is probably mediated through lipid peroxidation because the antitumour effect of n-3 PUFAs is shared with the n-6 PUFA, arachidonic acid, and abolished by antioxidants like vitamin E. Radio/chemotherapy kills cancer cells with oxidative stress (reactive oxygen species) among other mechanisms. Furthermore, omega 3 PUFA downregulate eicosanoid synthesis from cyclooxygenase II and reduce angiogenesis, inflammation and metastasis induction. Have a nice day and courage for your brother's friend. -- Frederic Courtois, RD, PhD Re: Pancreatic Cancer & Diet > Hi - > I'm an oncology dietitian and have had quite a few pancreatic ca pts > past few months. I'm not sure if the pt has had surgery (whipple) or > chemo/radiation yet. If the pt is just starting out with tx and feeling > good, I would rec increasing po intake with increased pro/carb and mod fat > intake. If po intake is poor and wt loss has begun - rec any high cal > foods tolerated > As far as nutritional supplements - I would start with Resurgex. I would > make sure the pt is on a proton-pump inhibitor (like protonix or nexium) > to reduce stomach acid. Also, there is a good hand out on the oncology > listserve about pancreatic enzymes. Pts with pancreatic ca often have > problems with malabsorption (fat) and benefit from pancreatic enzymes. > Pancrealipase MT is a good one to try. Symptoms of malabsorption include > foul smelling, oily stool, and GI complaints. Obviously, each pt is > different and there response to treatment and outcomes are very > individual, including susceptibility for cachexia. I have seen some > research recommending Omega 3 supplements to help decrease wt loss in > pancreatic pts. The evidence based recs say that fish oil does not have > strong evidence to support wt gain, but from anecdotal experience with > pts, I believe that it helps. I would rec 1000-2000mg EPA in the Omega 3 > supplement. Carlsons is a brand often preferred by pts. > I hope this helps. > If you can't get the pancreatic enzyme handout - I could email it to you. > > Baker, MS,RD > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 6, 2008 Report Share Posted January 6, 2008 Bonjour Frederic, Merci de me donner une explication merveilleuse Et soutien de mon ami -beth _____ From: rd-usa [mailto:rd-usa ] On Behalf Of Frederic Courtois Sent: Saturday, January 05, 2008 12:53 AM To: rd-usa Subject: Re: Pancreatic Cancer & Diet Hello beth, First, thanks ! I didn't know omega 3 PUFA can help decrease wt loss in pancreatic pts (anti-cachexia effect). I knew omega 3 PUFA are very useful during radio/chemotherapy as they seems to increase the cytotoxicity of several anticancer drugs. The mechanism is probably mediated through lipid peroxidation because the antitumour effect of n-3 PUFAs is shared with the n-6 PUFA, arachidonic acid, and abolished by antioxidants like vitamin E. Radio/chemotherapy kills cancer cells with oxidative stress (reactive oxygen species) among other mechanisms. Furthermore, omega 3 PUFA downregulate eicosanoid synthesis from cyclooxygenase II and reduce angiogenesis, inflammation and metastasis induction. Have a nice day and courage for your brother's friend. -- Frederic Courtois, RD, PhD Re: Pancreatic Cancer & Diet > Hi - > I'm an oncology dietitian and have had quite a few pancreatic ca pts > past few months. I'm not sure if the pt has had surgery (whipple) or > chemo/radiation yet. If the pt is just starting out with tx and feeling > good, I would rec increasing po intake with increased pro/carb and mod fat > intake. If po intake is poor and wt loss has begun - rec any high cal > foods tolerated > As far as nutritional supplements - I would start with Resurgex. I would > make sure the pt is on a proton-pump inhibitor (like protonix or nexium) > to reduce stomach acid. Also, there is a good hand out on the oncology > listserve about pancreatic enzymes. Pts with pancreatic ca often have > problems with malabsorption (fat) and benefit from pancreatic enzymes. > Pancrealipase MT is a good one to try. Symptoms of malabsorption include > foul smelling, oily stool, and GI complaints. Obviously, each pt is > different and there response to treatment and outcomes are very > individual, including susceptibility for cachexia. I have seen some > research recommending Omega 3 supplements to help decrease wt loss in > pancreatic pts. The evidence based recs say that fish oil does not have > strong evidence to support wt gain, but from anecdotal experience with > pts, I believe that it helps. I would rec 1000-2000mg EPA in the Omega 3 > supplement. Carlsons is a brand often preferred by pts. > I hope this helps. > If you can't get the pancreatic enzyme handout - I could email it to you. > > Baker, MS,RD > No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 6, 2008 Report Share Posted January 6, 2008 Bonjour Frederic, Merci de me donner une explication merveilleuse Et soutien de mon ami -beth _____ From: rd-usa [mailto:rd-usa ] On Behalf Of Frederic Courtois Sent: Saturday, January 05, 2008 12:53 AM To: rd-usa Subject: Re: Pancreatic Cancer & Diet Hello beth, First, thanks ! I didn't know omega 3 PUFA can help decrease wt loss in pancreatic pts (anti-cachexia effect). I knew omega 3 PUFA are very useful during radio/chemotherapy as they seems to increase the cytotoxicity of several anticancer drugs. The mechanism is probably mediated through lipid peroxidation because the antitumour effect of n-3 PUFAs is shared with the n-6 PUFA, arachidonic acid, and abolished by antioxidants like vitamin E. Radio/chemotherapy kills cancer cells with oxidative stress (reactive oxygen species) among other mechanisms. Furthermore, omega 3 PUFA downregulate eicosanoid synthesis from cyclooxygenase II and reduce angiogenesis, inflammation and metastasis induction. Have a nice day and courage for your brother's friend. -- Frederic Courtois, RD, PhD Re: Pancreatic Cancer & Diet > Hi - > I'm an oncology dietitian and have had quite a few pancreatic ca pts > past few months. I'm not sure if the pt has had surgery (whipple) or > chemo/radiation yet. If the pt is just starting out with tx and feeling > good, I would rec increasing po intake with increased pro/carb and mod fat > intake. If po intake is poor and wt loss has begun - rec any high cal > foods tolerated > As far as nutritional supplements - I would start with Resurgex. I would > make sure the pt is on a proton-pump inhibitor (like protonix or nexium) > to reduce stomach acid. Also, there is a good hand out on the oncology > listserve about pancreatic enzymes. Pts with pancreatic ca often have > problems with malabsorption (fat) and benefit from pancreatic enzymes. > Pancrealipase MT is a good one to try. Symptoms of malabsorption include > foul smelling, oily stool, and GI complaints. Obviously, each pt is > different and there response to treatment and outcomes are very > individual, including susceptibility for cachexia. I have seen some > research recommending Omega 3 supplements to help decrease wt loss in > pancreatic pts. The evidence based recs say that fish oil does not have > strong evidence to support wt gain, but from anecdotal experience with > pts, I believe that it helps. I would rec 1000-2000mg EPA in the Omega 3 > supplement. Carlsons is a brand often preferred by pts. > I hope this helps. > If you can't get the pancreatic enzyme handout - I could email it to you. > > Baker, MS,RD > No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2008 Report Share Posted January 7, 2008 Hello beth, Wow, when I red your message, I thougth I was on my french yahoogroups dieteticien-nes !!!! Nice french ! Your welcome !!!! If I've time enough, I'll try to go to medline and see what I get with keywords like nutrition & pancreatic cancer for example. -- Frederic Courtois, RD, PhD RE: Pancreatic Cancer & Diet > Bonjour Frederic, > Merci de me donner une explication merveilleuse > > Et soutien de mon ami > > > > -beth > > > _____ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2008 Report Share Posted January 7, 2008 Hello Frederic, I am happy that my French was OK but it has been 20 years since I have studied. I really can't speak French very well anymore. Writing gives one plenty of time to think, research & edit Thank you for offering to look up info on Pubmed. I did do a lit search & mainly found tools for " prevention " of Pancreatic Cancer. As we know, the survival rate is dismal at best. But at least I can offer this advice to my friend. I have just learned that his brother has Stage IV Cancer. As for prevention; more whole grains, more fruits & vegetables & elimination of animal protein cooked at high heat. All the stuff I already preach I did find one article on the benefits of COX-2 inhibitors on Pancreatic Cancer. This also lead me to look to fish & fish oil supplements as well as possibly flax seed as these sources of Omega-3s will stimulate the body's natural anti-inflammatory pathways I was very happy to read that the oncology RD's recommend Fish oil supplements. I am a Holistic Chef as well so I looked for Holistic Approaches to fighting this fatal disease. I saw that UCLA was top in Pancreatic Cancer research. I found an MD affiliated with UCLA who specializes in Holistic Approaches to treating Pancreatic Cancer. He is a Plastic Surgeon living in Israel but he has a special interest in Pancreatic Cancer because he lost four family members from it. He had been tested himself & there were markers to indicate that he too was a candidate, hence his interest. I emailed him about my friend's brother and he emailed me back the next day. He is coming to the US to visit family this month. He gave me the dates of his trip & the phone number where he can be reached. He wants to speak directly to the patient. I was so taken aback by his immediate response and offer. For those interested in this subject I will share with you any information once the call has been completed. Thanks for everyone's help. Sincerely, _____ From: rd-usa [mailto:rd-usa ] On Behalf Of Frederic Courtois Sent: Monday, January 07, 2008 4:20 AM To: rd-usa Subject: Re: Pancreatic Cancer & Diet Hello beth, Wow, when I red your message, I thougth I was on my french yahoogroups dieteticien--nes !!!! Nice french ! Your welcome !!!! If I've time enough, I'll try to go to medline and see what I get with keywords like nutrition & pancreatic cancer for example. -- Frederic Courtois, RD, PhD RE: Pancreatic Cancer & Diet > Bonjour Frederic, > Merci de me donner une explication merveilleuse > > Et soutien de mon ami > > > > -beth > > > _____ No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 1/6/2008 11:57 AM Quote Link to comment Share on other sites More sharing options...
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