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Infant pesticide exposure - huge variance between individuals

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The findings are fraught with significance - for understanding subgroups

affected by organochlorines, for reshaping the notion of " safe " levels.

* * * *

May 3, 2006

http://pubs.acs.org/subscribe/journals/esthag-w/2006/may/science/kb_pesticide.ht\

ml

*

Infant pesticide exposure*

*Organophosphates may be more dangerous to small children than

previously believed.*

Some infants may be far more vulnerable to organophosphate pesticides

than previously believed, according to a paper published in

/Pharmacogenetics and Genomics/ (*2006*, /16/, 183-190

<http://www.jpharmacogenetics.com/pt/re/pharmgen/abstract.01213011-200603000-000\

04.htm;jsessionid=E7uZJj6opqZVKKwd9WrO2r5n0ym9lTtBoZRrAiRDybipQHo16giD%21-155117\

8825%21-949856144%219001%21-1>).

The new study " raises the question of whether current standards for safe

levels of pesticide exposure are sufficiently protective of a vulnerable

population, " says Nina Holland, an adjunct professor of environmental

health sciences at the University of California, Berkeley, and coauthor

of the paper.

Current U.S. EPA standards require an extra 10-fold safety factor to

protect children

<http://www.epa.gov/pesticides/factsheets/kidpesticide.htm> compared

with adults. But the new study shows that some newborns may be 65 to 130

times more sensitive to these pesticides than some adults, a level of

susceptibility 26 to 50 times higher than previously believed.

Of the 130 Latina women who participated in the study with their

newborns, more than 40% worked in agriculture during their pregnancies.

The Berkeley researchers measured levels of paraoxonase 1, an enzyme

that breaks down the toxic metabolites of organophosphates, as a marker

for pesticide susceptibility.

*

Body Burden Case Study: *Organochlorine Pesticides*

<http://www.chemicalbodyburden.org/cs_organochl.htm>

Chemical body burden is the build-up of synthetic chemicals and heavy

metals in our bodies, which can have negative health effects as

discussed in this web *...*

www.chemicalbodyburden.org/cs_organochl.htm - 20k -

<http://www.google.com/search?hl=en & hs=of1 & lr= & safe=off & client=firefox-a & rls=org\

..mozilla:en-US:official & q=related:www.chemicalbodyburden.org/cs_organochl.htm>

*ORGANOCHLORINE PESTICIDES*

<http://www.scorecard.org/about/txt/organochlorine_pesticides.html>

*Organochlorine pesticides* are man-made organic chemicals. *...* Many

*organochlorine* *pesticides* are extremely persistent in the

environment and in people's *...*

www.scorecard.org/about/txt/*organochlorine*_*pesticides*.html - 19k -

<http://www.google.com/search?hl=en & hs=of1 & lr= & safe=off & client=firefox-a & rls=org\

..mozilla:en-US:official & q=related:www.scorecard.org/about/txt/organochlorine_pes\

ticides.html>

*ORGANOCHLORINE PESTICIDES*

<http://www.scorecard.org/chemical-profiles/summary.tcl?edf_substance_id=EDF-175\

>

Chemical Profile for *ORGANOCHLORINE PESTICIDES* (CAS Number:

EDF-175). Human Health Hazards; Hazard Rankings; Chemical Use

Profile *...*

www.scorecard.org/chemical-profiles/summary.tcl?edf_substance_id=EDF-175

- 25k -

<http://www.google.com/search?hl=en & hs=of1 & lr= & safe=off & client=firefox-a & rls=org\

..mozilla:en-US:official & q=related:www.scorecard.org/chemical-profiles/summary.tc\

l%3Fedf_substance_id%3DEDF-175>

*

[PDF]* CDC's Third National Report on Human Exposure to Environmental

*...*

<http://www.cdc.gov/exposurereport/pdf/factsheet_organochlorine.pdf>

File Format: PDF/Adobe Acrobat -

*Organochlorine pesticides* were introduced in the 1940s and persist in

the *...* *Organochlorine pesticides* can produce reproductive and

neurologic effects in *...*

www.cdc.gov/exposurereport/pdf/factsheet_*organochlorine*.pdf -

*

[PDF]* A Closer Look at *Organochlorine Pesticides*

<http://www.akaction.org/fact_sheets/Organochlorine_Pesticide_Fact_Sheet.pdf>

File Format: PDF/Adobe Acrobat -

*Organochlorine pesticides* are insecticides composed. primarily of

carbon, hydrogen, and chlorine *...* Infants are also exposed when

*organochlorine pesticides* *...*

www.akaction.org/fact_sheets/Organochlorine_Pesticide_Fact_Sheet.pdf -

Chemical fact sheet: *Organochlorine* - The Breast Cancer Fund

<http://www.breastcancerfund.org/site/pp.asp?c=kwKXLdPaE & b=84567> The

Breast Cancer Fund's fact sheet on *organochlorine pesticides*. The

Breast Cancer Fund is the only national non-profit organization whose

sole focus is to *...*

www.breastcancerfund.org/site/pp.asp?c=kwKXLdPaE & b=84567 - 33k -

Environmental Health Perspectives: Acceleration of autoimmunity by *...*

<http://www.findarticles.com/p/articles/mi_m0CYP/is_3_113/ai_n13559721>

Acceleration of autoimmunity by *organochlorine pesticides* in [F.sub.1]

mice *...* Three *organochlorine pesticides* with estrogenic effects

were administered *...*

www.findarticles.com/p/articles/mi_m0CYP/is_3_113/ai_n13559721 - 25k

*

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in receiving the included information for research

and educational purposes. For more information go to:

http://www4.law.cornell.edu/uscode/17/107.html

http://oregon.uoregon.edu/~csundt/documents.htm

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