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Supplementation with Probiotics May Enhance Eradication of H. Pylori

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Supplementation with Probiotics May Enhance Eradication of H. Pylori

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " The effect of probiotics on Helicobacter pylori

eradication, " Park SK, Park DI, et al, Hepatogastroenterology, 2007;

54(79): 2032-6. (Address: Department of Internal Medicine, Kangbuk

Samsung Hospital, Sungkyunkwan University School of Medicine, Jongno-gu,

Seoul 110-746, Korea).

Summary: In a study involving 352 patients infected with Helicobacter

pylori, supplementation with probiotics was found to improve drug

compliance, reduce side effects, and enhance the intention-to-treat

eradication rate of H. pylori. Subjects were randomized into 2 groups.

One group received probiotics (bacillus subtilis and Streptococcus

faecium) plus standard triple therapy (2 antibiotics plus a proton pump

inhibitor), while the other group received standard triple therapy

alone. Probiotics were given for 8 weeks. Four weeks after completion of

therapy, results of intention to treat analysis found that subjects in

the probiotics group experienced higher eradication of H. pylori

(83.5%), compared to subjects in the triple therapy alone group (73.3%).

Side effects of triple therapy, including diarrhea, were more common in

the triple therapy alone group. Results of this study suggest that

adding probiotic supplementation to standard pharmacological therapy

used to treat H. pylor i infection ('triple therapy') may enhance

eradication of H. pylori and reduce side effects, thereby rendering

treatment more tolerable and effective.

--

ne Holden, MS, RD

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/

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