Remission in RA

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J Rheumatol. 1985 Apr;12(2):245-52.

Remission in rheumatoid arthritis.

Wolfe F, Hawley DJ.

Four hundred and fifty-eight patients whose clinical data had been

prospectively entered into a rheumatic disease databank were studied for

remission utilizing remission criteria of the American Rheumatism

Association and criteria modified for chart review. During the period of

observation 86 of 458 or 18.8% had at least one remission by

investigators' assessment on chart review and 18.1% by application of

ARA criteria. Patients were followed for 1131 patient years and

remission occupied 97 patient years. For patients achieving remission

this period represented 34.5% of their followup duration. The median

length of remission was 10 months. Nineteen (18.6) percent of gold

treatment courses and 16.7% of penicillamine courses resulted in

remission. Fourteen (13.6) percent of patients who never received

remittive therapy also had remissions. The ARA Preliminary Criteria for

Clinical Remission in Rheumatoid Arthritis displayed a sensitivity of

80.2% and a specificity of 96.2% in this population. In patients

receiving remittive therapy, female sex, disease onset before age 60,

and early development of erosions were associated with decreased

proportion of remission.

PMID: 4032401

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