Vitamin D Depletion Very Common in Patients Seeking Osteoporosis Advice

February 21, 2008

Colleagues, the following is FYI and does not necessarily reflect my own

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Vitamin D Depletion Very Common in Patients Seeking Osteoporosis Advice

Reference: " Prevalence of vitamin D depletion among subjects seeking

advice on osteoporosis: a five-year cross-sectional study with public

health implications, " Guardia G, Parikh N, et al, Osteoporos Int, 2008;

19(1): 13-9. (Address: Sudhaker Rao, Bone & Mineral Research Laboratory,

Henry Ford Hospital, Detroit, MI, USA. E-mail: srao1@... ).

Summary: In a cross-sectional study involving 2,924 patients (mean age:

68.3 years; 90% women; 88% white) seeking osteoporosis advice, vitamin D

depletion - assessed by measuring levels of 25-hydroxyvitamin D - was

found to be highly prevalent. The mean 25(OH)D in subjects was 24.6

ng/ml, and the mean PTH was 48.4 pg/ml. Vitamin D depletion was found in

72% of subjects, when the cutoff was defined as having 25(OH)D level

less than 30 ng/mL. When the cutoff was defined as less than 20 ng/ml,

the prevalence decreased to 32%, and when the cutoff was defined as less

than 15 ng/ml, the prevalence further decreased to 15%. Cut-off levels

were stratified by gender, race, and the year of the study over 5 years.

Regardless of the cut-off level, men and blacks were found to have a

higher prevalence of vitamin D depletion. An inverse relationship was

found between 25(OH)D and PTH in all groups of subjects. The authors

conclude, " The prevalence of vitamin D depletion in patients seeking ad

vice for osteoporosis is high and did not change over the 5 years of the

study. "

--

ne Holden, MS, RD

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

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