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Could the BASDAI be a valid measure of disease activity in patients with psoriatic arthritis?

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Arthritis Rheum. 2004 Jun 15;51(3):311-5.

Could the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) be

a valid measure of disease activity in patients with psoriatic

arthritis?

WJ, on AA.

Wellington Regional Rheumatology Unit, Hutt Valley District Health

Board, Lower Hutt, New Zealand. wtaylor@...

OBJECTIVE: To determine whether the Bath Ankylosing Spondylitis Disease

Activity Index (BASDAI) could be a valid indicator of disease activity

in psoriatic arthritis (PsA). METHODS: Patients with PsA identified from

a disease-register and case-note review answered a questionnaire by mail

(n = 133); some patients (n = 86) consented to examination. In a second

sample of 47 consecutive clinic attendees with PsA, logistic regression

examined the independent contribution of BASDAI to disease activity, as

judged by treatment decisions at that time. RESULTS: BASDAI correlated

highly with patient perception of disease activity (r = 0.739) and there

was no significant effect of the pattern of disease (axial or

peripheral) on this relationship. However, only physician perception of

disease activity was significantly associated with high or low disease

activity (odds ratio 18.4, 95% confidence interval 2.9-118.3). BASDAI,

patient perception, and erythrocyte sedimentation rate failed to

contribute significantly to the model.

CONCLUSION: BASDAI performs similarly for axial and peripheral PsA but

does not correlate well with external indicators of disease activity,

such as treatment decisions.

PMID: 15188312

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

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