Vitamin D Inadequacy Highly Prevalent in Osteoporotic Postmenopausal Women

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Vitamin D Inadequacy Highly Prevalent in Osteoporotic Postmenopausal Women

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " Vitamin D inadequacy in Belgian postmenopausal osteoporotic

women, " Neuprez A, Bruyere O, et al, BMC Public Health, 2007; 7(147):

64. (Address: Department of Epidemiology, Public Health and Health

Economics, University of Liege, 4020 Liege, Belgium. E-mail:

Audrey.Neuprez@... ).

Summary: In a study involving 1,195 osteoporotic postmenopausal Belgian

women over the age of 50 years (mean age: 76.9 years, mean BMI: 25.7

kg/m(2)), inadequate levels of vitamin D were found to be highly

prevalent, including among women supplementing with vitamin D. Vitamin D

inadequacy was defined by four different cut-offs, since there is no

clear consensus as to what constitutes vitamin D inadequacy. The

prevalence of vitamin D inadequacy, according to the four cut-offs were:

91.3% for < 80 nmol/L, 87.5% for < 75 nmol/L, 43.1% for < 50 nmol/L, and

15.9% for < 30 nmol/L. The mean concentration of 25(OH)D was found to be

52.5 nmol/L. Significant inverse associations were found between

age/serum PTH and serum 25(OH)D, and between age/serum PTH and femoral

neck BMD, while a significant positive association was found between age

and PTH, serum 25(OH)D, and femoral neck BMD. The authors conclude,

" This study points out a high prevalence of vitamin D inadequacy in

Belgian postmenopausal osteoporotic women, even among subjects receiving

vitamin D supplements. " Vitasearch Comment: This study points to the

need for Vitamin D supplementation at levels higher than currently

recommended.

--

ne Holden, MS, RD

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