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Re: PSC hereditary??

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Dear Adam,

I too am terrified at the prospect that PSC could be passed down to our

babies. In 1995, I was told by Dr. Van Thiel (helped invent the tx)

that my children would have a one in four chance of getting it. We kind of

blew off the advice at the time, but then last year when my dear friend, the

pastor from Denver died, his wife sent me an article about him because he was

so loved all over the world. The article said that his 22 year old son had

just been dx with PSC 2 years prior. I called Mike's wife to confirm this

and she said that is was true.

That is my only info about it. All we can do is pray that it's as you

said....some kind of fluke!!

Take care and God Bless!

Jacquelyn

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Jacquelyn,

Dr. Van Thiel was mistaken. No even knows if PSC is hereditary. And

even if it was a recessive (single allele) genetic trait, your husband would

also have to be a carrier. And based upon the incidence of PSC, this is very

unlikely. And even if he was a carrier, the odds would be one in two not one

in four. Though this doctor may be brilliant, he needs to review his basic

high school biology and quit scaring people.

Adam (Science teacher in CA, expecting first child in Aug, not worried about

her having PSC)

PS Did the preacher you mentioned below also have PSC or just his son?

In a message dated 5/12/00 7:50:06 PM Pacific Daylight Time, Jqs2@...

writes:

> Dear Adam,

> I too am terrified at the prospect that PSC could be passed down to

our

> babies. In 1995, I was told by Dr. Van Thiel (helped invent the tx)

> that my children would have a one in four chance of getting it. We kind

of

> blew off the advice at the time, but then last year when my dear friend,

the

> pastor from Denver died, his wife sent me an article about him because he

> was so loved all over the world. The article said that his 22 year old

son had

> just been dx with PSC 2 years prior. I called Mike's wife to confirm this

> and she said that is was true.

> That is my only info about it. All we can do is pray that it's as you

> said....some kind of fluke!!

> Take care and God Bless!

> Jacquelyn

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