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Cary - regarding the coxibs

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It's a tough one, Cary. And I'm worried, too. I believe that nobody

knows for sure yet, but, as you can see from the flurry of recent news

reports, there is some evidence to suggest that the cardiovascular side

effects are a class effect and not unique to Vioxx (rofecoxib).

Not only that, but Vioxx seemed to be better at sparing the gut than the

other coxibs, too.

I'd say that people with RA should use Bextra (valdecoxib) and Celebrex

(celecoxib) with caution and only after making sure there aren't safer

alternatives available to them. If the coxibs are used, being on them

for the shortest time possible would also be prudent.

Sorry for such a late reply!

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

Re: [ ] NEWS - FDA withholds approval of new arthritis

drug

>

> I take Bextra, which works fairly well for me. Celebrex did nothing,

and steady doses of ibuprofen make me feel like a rat is attempting to

gnaw it's way out of my stomach. I worry though-with RA we are already

at greater risk for cardiovascular problems, and I worry that even if

Bextra is considered relatively safe for the average person, what about

the person with a greater risk for cardiovascular events? ,

a...? Whaddya think? Cary

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