Vitamin D Deficiency in Obese Patients after Bariatric Surgery

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Vitamin D Deficiency in Obese Patients after Bariatric Surgery

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " Prevalence of Vitamin D Insufficiency and Deficiency in

Morbidly Obese Patients: A Comparison with Non-Obese Controls, " Goldner

WS, Stoner JA, et al, Obes Surg, 2008 Jan 4; [Epub ahead of print].

(Address: Department of Internal Medicine, Section of Diabetes,

Endocrinology, and Metabolism, University of Nebraska Medical Center,

Omaha, NE, 68198-3020, USA. E-mail: wgoldner@... ).

Summary: In a study involving 41 obese patients undergoing Roux-en-Y

gastric bypass, vitamin D deficiency was found to be significantly more

prevalent among subjects, as compared to healthy, non-obese controls.

Prior to bariatric surgery, 90% of the obese subjects had 25(OH)D levels

less than 75 nmol/l and 61% had 25(OH)D levels less than 50 nmol/l. In

controls, 25(OH)D levels less than 75 nmol/l were found in 32% of

subjects, and 25(OH)D levels less than 50 nmol/l were found in 12% of

subjects. The prevalence of secondary hyperparathyroidism among

pre-bariatric surgery obese patients was also quite high, with 49%

having secondary hyperparathyroidism, as compared to only 2% of

controls. Mean albumin levels were also significantly lower among

bariatric surgery patients as compared to non-obese controls. No

significant differences were found for levels of calcium (corrected for

albumin) and creatinine. The authors point out that vitamin D deficiency

is known to be prevalent in pat ients after gastric bypass due to

malabsorption. The results of this study suggest that this may in part

be due to a pre-existing vitamin D deficiency, which this study has

found to be quite common in obese patients prior to bariatric surgery.

--

ne Holden, MS, RD

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