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If dmards stop the progression...does that mean once you go off of it - it

progresses again...that would mean if so you would need to take them the rest

of your life ???? Jayne

>>

In most cases, I believe the answer to your question is " yes " . There have

got to be exceptions, just like there are for any other generalization. :-)

Patty

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Re: [ ] dmards

> From: PHDRWD@...

>

> If dmards stop the progression...does that mean once you go off of it - it

> progresses again...that would mean if so you would need to take them the

rest

> of your life ???? Jayne

> >>

> In most cases, I believe the answer to your question is " yes " . There have

> got to be exceptions, just like there are for any other generalization.

:-)

>

> Patty

>

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  • 2 months later...
Guest guest

Gloria,

I have never heard or read that dmards prevent joint damage, only that they

slow

the damage. They most often lose their effectiveness with time. I wonder who

on this list used dmards and antibiotics concurrently and had good results

which

held up after the dmards were discontinued. Also I would like to know which

dmards they were taking.

Ann

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Re: using DMARDS and AP concurrently, I used methotrexate and Minocin

concurrently with good results. Am off methotrexate since March and still on

Minocin - doing great so far.

Babs

RA 8/98, DX 4/99, AP 11/99

200 mg. Minocin

112 mcg. Synthroid

2 mg. Hytrin

10 mg. Lipitor

Mestinon

Vits. & Misc. Suplmts.

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> Gloria,

> I have never heard or read that dmards prevent joint damage, only

that they

> slow

> the damage. They most often lose their effectiveness with time. I

wonder who

> on this list used dmards and antibiotics concurrently and had good

results

> which

> held up after the dmards were discontinued. Also I would like to

know which

> dmards they were taking.

> Ann

I have been taking methotrexate since September of '99 along with

minocycline. I'm doing well on it (despite a slight flare recently,

which always seems to happen to me in the Spring. Booting the

methotrexate up to 15mg from 12.5mg seems to be helping with that). I

can't give you details on how I would be doing without the metho

because my doctor does not yet think it is time for me to experiment

going off of it. If I do reach that point, I'll let you know. I had

thought this was going to be a possibility until my latest new flare.

Although I continue to take the minocycline, I am skeptical of its

benefits. I am however, somewhat reluctant to stop taking it, as its

action when combined with methotrexate may be part of the reason I'm

doing so well over the past 9 months. I don't know for sure and

certainly no doctor knows.

Mark

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Hi,

So many of us start several new things at once, so we are never sure

what helps. I just want to say that there are plenty of people who have

taken minocycline with nothing else, and most of these people have ended

up experiencing great improvement or even remission of all their

symptoms. I know that it feels like alternative/weird

medicine, especially in view of many doctors' reactions, but it does

work.

Thanks and good luck,

Gloria

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  • 4 years later...

Hi all,

I'm wondering if you take a DMARD? and if so which one?

My biggest questions are- how long did it take for you to start to feel

relief from it and do you have a lot of morning stiffness?

Sorry for my ignorance and letting you know I appreciate your wisdom.

Thanks,

Abby

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It's probably safe to say that the majority of us with active RA are

on one or more DMARDs. I take MTX and it took effect right away when

I started it. I also take Humira and I felt improvement within the

first few days, although it's more common with a biological to have

improvement within a few months. I have never taken plaquinil but I

know that can take weeks or months to take effect.

I had lots of morning stiffness before I took MTX and then it creeped

back after I had been on it for a while, which is the reason we added

Humira. It's common for that to happen, you are on a drug that is

working well but the disease worsens and the drug doesn't cut it

anymore. That is when you increase the dosage or add another drug.

All in order to prevent joint destruction and enable us to function

on a daily basis.

Jennie

> Hi all,

> I'm wondering if you take a DMARD? and if so which one?

>

> My biggest questions are- how long did it take for you to start to

feel

> relief from it and do you have a lot of morning stiffness?

>

> Sorry for my ignorance and letting you know I appreciate your

wisdom.

>

> Thanks,

> Abby

>

>

>

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In a message dated 8/11/2004 7:26:44 AM Pacific Daylight Time,

xponder70@... writes:

It's probably safe to say that the majority of us with active RA are

on one or more DMARDs. I take MTX and it took effect right away when

I started it. I also take Humira and I felt improvement within the

first few days, although it's more common with a biological to have

improvement within a few months.

Thank you for the response. I have been taking Sulfasalazine for for two

weeks and felt better. It's been over a month now. I started with Prednisone 5mg

per day but stopped it after one week due to the depression. I was feeling

quite well. Very well. I've had a little bit of stiffness in the morning but

not too bad.

I recently had a VERY stressful situation and was hit like a ton of bricks

again and realized just HOW well I was feeling since starting the med. The

symptoms were back like gangbusters. I have taken a couple days of the

prednisone and am much better again. I was feeling so much better, that aside

from the

slight stiffness in the AM, I was beginning to think it was all in my head.

I was amazed at how this stress affected me. Just amazed and it also showed

me that the Sulfasalazine was doing something.

Abby

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In a message dated 8/15/2004 4:58:14 PM Pacific Daylight Time,

xponder70@... writes:

Does he/she know about stoping/starting the prednisone? I

know you are on a low dose and haven't been on it for long, but

usually you must wean off of it, otherwise you can experience

extremely severe side effects. It can also throw you into an RA

flare. Just another thing to be talking to your rheumy about to

ensure you are being treated in the best way possible.

Jennie

No, she doesn't know I'm not taking it regularly, I don't see her again

until October. When I had the reaction to Plaquenil, she let me titrate some

Prednisone I had at home since I am an NP.

Abby

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In a message dated 8/15/2004 4:58:14 PM Pacific Daylight Time,

xponder70@... writes:

Since RA is progressive, it's common for your meds to one day not

work as well. That is when you need to discuss your meds with your

rheumy. Does he/she know about stoping/starting the prednisone? I

know you are on a low dose and haven't been on it for long, but

usually you must wean off of it, otherwise you can experience

extremely severe side effects.

I will make sure I talk to her about all of this. It's all new in this

respect. I'm glad you all are here to bounce things off of. I didn't realize the

Sulfasalazine to be working so well .. and I certainly didn't realize that

stress would affect me so profoundly.

Abby

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I'm glad the medicine is working. Just so you know, you need to

keep your doctor informed if the medicine stops working as well.

Since RA is progressive, it's common for your meds to one day not

work as well. That is when you need to discuss your meds with your

rheumy. Does he/she know about stoping/starting the prednisone? I

know you are on a low dose and haven't been on it for long, but

usually you must wean off of it, otherwise you can experience

extremely severe side effects. It can also throw you into an RA

flare. Just another thing to be talking to your rheumy about to

ensure you are being treated in the best way possible.

Jennie

>

> In a message dated 8/11/2004 7:26:44 AM Pacific Daylight Time,

> xponder70@y... writes:

>

> It's probably safe to say that the majority of us with active RA

are

> on one or more DMARDs. I take MTX and it took effect right away

when

> I started it. I also take Humira and I felt improvement within

the

> first few days, although it's more common with a biological to

have

> improvement within a few months.

>

>

> Thank you for the response. I have been taking Sulfasalazine for

for two

> weeks and felt better. It's been over a month now. I started with

Prednisone 5mg

> per day but stopped it after one week due to the depression. I was

feeling

> quite well. Very well. I've had a little bit of stiffness in the

morning but

> not too bad.

>

> I recently had a VERY stressful situation and was hit like a ton

of bricks

> again and realized just HOW well I was feeling since starting the

med. The

> symptoms were back like gangbusters. I have taken a couple days of

the

> prednisone and am much better again. I was feeling so much better,

that aside from the

> slight stiffness in the AM, I was beginning to think it was all in

my head.

>

> I was amazed at how this stress affected me. Just amazed and it

also showed

> me that the Sulfasalazine was doing something.

>

> Abby

>

>

>

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