Health related quality of life in multiple musculoskeletal diseases: SF-36 and EQ-5D in the DMC3 study

[Guest guest]

Ann Rheum Dis. 2004 Jun;63(6):723-9.

Health related quality of life in multiple musculoskeletal diseases:

SF-36 and EQ-5D in the DMC3 study.

Picavet HS, Hoeymans N.

Department for Prevention and Health Services Research (PZO, pb 101),

National Institute of Public Health and the Environment, PO Box 1, 3720

BA Bilthoven, Netherlands. susan.picavet@...

OBJECTIVE: To examine the health related quality of life of persons with

one or more self reported musculoskeletal diseases, as measured by the

short form 36 item health status survey (SF-36) and the Euroqol

questionnaire (EQ-5D). METHODS: A sample of Dutch inhabitants aged 25

years or more (n = 3664) participated in a questionnaire survey. Twelve

lay descriptions of common musculoskeletal diseases were presented and

the subjects were asked whether they had ever been told by a physician

that they had any of these. Their responses were used to assess the

prevalence of these conditions. Commonly used scores of SF-36 and

descriptive scores from EQ-5D are presented, along with standardised

differences between disease groups and the general population. RESULTS:

SUBJECTS: with musculoskeletal diseases had significantly lower scores

on all SF-36 dimensions than those without musculoskeletal disease,

especially for physical functioning (SF-36 score (SE), 75.2 (0.5) v 87.8

(0.5)); role limitations caused by physical problems (67.1 (0.9) v 85.8

(0.8)); and bodily pain (68.5 (0.5) v 84.1 (0.5)). The worst health

related quality of life patterns were found for osteoarthritis of the

hip, osteoporosis, rheumatoid arthritis, and fibromyalgia. Those with

multiple musculoskeletal diseases had the poorest health related quality

of life. Similar results were found for EQ-5D.

CONCLUSIONS: All musculoskeletal diseases involve pain and reduced

physical function. The coexistence of musculoskeletal diseases should be

taken into account in research and clinical practice because of its high

prevalence and its substantial impact on health related quality of life.

PMID: 15140781

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org