Pre-prostatectomy PSA Level Is Prognostic For Predicting Biochemical Failure After Surgery

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Pre-prostatectomy PSA Level Is Prognostic For Predicting Biochemical

Failure After Surgery

Article Date: 12 Aug 2006 - 6:00am (PDT)

|Article Also Appears In Prostate

UroToday.com - The clinical utility of PSA has come into question

regarding its ability to diagnose clinically significant prostate cancer

(CaP) as opposed to BPH. In the May 2006 issue of the Journal of

Urology, Dr. and colleagues at Columbia University report that

pre-operative PSA is predictive of biochemical failure (BCF) following

radical prostatectomy (RP) over a 15-year period.

A database search resulted in analysis of 1,246 patients who had RP and

bilateral pelvic lymph node dissection. Clinicopathologic variables were

compared across 3 time periods; 1988-1993, 1994-1998, and 1999-2003.

Patients who received adjuvant therapy were excluded.

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Kathy Meade

Arlington Educational Consulting

http://www.vapcacoalition.org/

http://www.naspcc.org/

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