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Phil

Yes, there is a difference between these two amino acids. DL-phenylalanine contains BOTH the D form and the L form oh phenylalanine. Some people do not tolerate it well because of a conversion problem but get benefit from l-Tyrosine which is made in the body by DLPA.

Hope this helps

Date: Sat, 22 Apr 2006 15:38:22 -0000 From: "unitedviv" <unitedviv@...>Subject: Is there any difference between DL-Phenylalanine and L-Phenylalanine?Phil

mjh"The Basil Book"http://foxhillfarm.us/FireBasil/

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Do you know if the DL form is available in Australia?

Also is it ok to take it with anti-depressants?

Re: [low dose naltrexone] Re: Phenylalanine

Definitely, Phil! It must be the DL form for helping LDN.unitedviv wrote:

Is there any difference between DL-Phenylalanine and L-Phenylalanine?Phil

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I tried to find it here in Australia and finally found a place in Perth

with it on their website so ordered two bottles. When it arrived

however it was only the L form, not the DL form so I had to send it

back. Conclusion I have come to is it is not available here (or may

only be available on prescription).

iherb.com where I get all my antioxidants from that are not available

here or too expensive here have it so next time I put an order in

(soon) I am going to get some DLP too - it's not very expensive but to

order it alone would be impractical due to the shipping charges. If

you are interested I could order some for you and that way the extra

shipping charges will be very small.

I don't know if it is OK to take with anti-depressants but I gather

that with LDN and DLP you shouldn't need them. Since starting on LDN I

have long ago weaned myself off anti-depressants.

Da Costa wrote:

Do you know if the DL form is

available in Australia?

Also is it ok to take it with

anti-depressants?

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I just saw this post but wanted to add I bought this on the internet. At neurotransmitters b-calmed. There is a phone number on the site and I would recommend talking to the girl or at least email her. There are definate DO's and DONT'S per condition and she helps guide you to the product you need. Questions? Just ask, wendy. Da Costa <topazblue@...> wrote: Do you know if the DL form is available in Australia? Also is it ok to take it with anti-depressants? Re: [low dose naltrexone] Re: Phenylalanine Definitely, Phil! It must be the DL form for helping LDN.unitedviv wrote: Is there any difference between DL-Phenylalanine and L-Phenylalanine?Phil

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  • 2 years later...

I received my custom aminio acids from Dr. Cliff Sheats and notice that they

have a warning on the back that says, " Phenylketonurics- Contains

Phenylalanine " . When I looked this up, it was not good. First of all, 50% of

Aspartame contains this, and aspartame is poison in my

opinion. There were also a couple of articles on the NIH website talking about

the potential neurotoxicity of phenylalanine.

Any info on this would be great. So far, not terribly impressed with my very

expensive experience with Dr. Sheats.

Thanks,

Amy

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Diet Coke contains phenylalanine, a mild mood enhancer. That's why Diet Coke

drinkers are so avid about their sodas.

A former co-worker was a DC fan and started having seizures. Lost his driver

license and everything. Then his father read where phenylalanine could cause

siezures, so he stopped drinking the diet cokes and stopped having siezures.

After a year he got his license back.

O

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Hi Mark,

I don't know the content, but maybe you might want to contact Coke to ask about

the Phenylalanine content.

http://www.thecoca-colacompany.com/contactus/index.html

http://www.thecoca-colacompany.com/contactus/cokefeedback/index.html

The Coca-Cola Company

P.O. Box 1734

Atlanta, GA 30301 USA

You may also be interested in this:

Nutritionists advise that Coca-Cola and other soft drinks can be

harmful if consumed excessively, particularly to young children whose

soft drink consumption competes with, rather than complements, a

balanced diet. Studies have shown that regular soft drink users have

a lower intake of calcium, magnesium, ascorbic acid, riboflavin, and

vitamin A. http://en.wikipedia.org/wiki/Coca-Cola#Formula

Those of us with CMT need our calcium and magnesium among others.

Gretchen

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Hi Mark,

 

The FDA's ADI (allowable daily intake) of Aspartame is the equivalent of about

20 - 12 oz cans of diet soda for a 150 lb man.

 

When setting an ADI amount, the FDA typically uses an amount 100 times less than

what they really feel is safe, i.e. the amount of Aspartame in 200 cans of soda

for a 150 lb man.

 

Phenylalanine, a component of Aspartame, is an amino acid that is also found in

protein, like milk and meat products.  When you consume animal-based protein,

you are consuming phenylalanine.

 

According to the FDA, Aspartame has been studied for decades and to date, there

have been no scientific studies that conclusively link it to cancer or any of

the other diseases that many claim aspartame causes, including neurologic

disorders. 

 

http://www.ncbi.nlm.nih.gov/pubmed/17828671?ordinalpos=1 & itool=EntrezSystem2.PEn\

trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA & linkpo\

s=3 & log$=relatedreviews & logdbfrom=pubmed

 

http://www.fda.gov/FDAC/features/1999/699_sugar.html

 

There are a small percentage of people with a genetic disorder, PKU,

that prohibits the body from processing the amino acid, phenylalanine,

properly.  These people need to avoid it.  A blood test can be taken to

determine if a person has this genetic disorder.  Also, pregnant women should

avoid consuming Aspartame, if they have high levels of phenylalanine in their

blood.

 

Nonetheless, there is still much wisdom in the centuries old adage, " All things

in moderation " .  And, just because research studies have been " inconclusive " ,

doesn't mean something is good for us.

 

Consuming 12 cans of soda is a lot and Aspartame isn't the only ingredient in

diet soda.  There's also carbonation, phosphoric acid, and caffeine.  Each of

these things can also have their own issues, especially when not consumed in

moderation.

 

Health professionals that I've spoken with recommend limiting consumption to no

more than 1-2 cans per day and then drinking it through a straw to help protect

teeth.

 

Recommended low calorie substitutes include black coffee/tea (also in

moderation) and water.  To flavor water, add a slice of lemon or lime.

 

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As a doctor, I can't let this go without comment. Phenylalanine is

one of the many amino acids that are found in all proteins. The

amino acids as a class are some of the most important molecules to

sustain life. So, there is nothing inherently " bad " about

phenylalanine. Just as with most substances (including water),

consuming it in huge quantities can be dangerous. My grandmother

gave me the best medical advice ever: " Everything in moderation,

do " . When a " good " food is taken to excess or a " bad " food is

strictly banned there may be hidden reprecussions down the road.

The warning to phenylketonurics is not relevant to the rest of us.

Phenylketonuria is an inherited disorder that disrupts the

processing on this particular amino acid allowing toxic levels of a

by-product to build up in the cells. It is extremely rare and in

infants and children who are undiagnosed, a normal level of

phenylalanine will cause mental retardation. Those of us who process

it normally don't need to worry about phenylketonuria.

BTW - to the guy who drinks 12 Cokes a day -- that ain't moderation!

It would be better for you all around to cut it down significantly.

Try some other beverages.... water?

Dr. Holli

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If you have CMT, as most of you do, you should really do your research on these

artificial sweeteners.

A good friend of ours who is a well known author in France wrote a book called

" Toxic " . It is all about the bad health effects of sweeteners such as aspartame

and the corruption between the FDA and Monsanto, the company that made (still

makes) aspartame. There are scientific studies showing rats that are given high

doses of aspartame, developing brain tumors. You may say rats aren't human, but

I don't want to be ingesting something that could potentially give me brain

tumors. As CMTers, we are hoping that the same thing that happened to the rats

with Vit C, will happen to us!

Worth exploring if you are addicted to Diet drinks...and, it's worth noting that

the FDA has just approved stevia for use in Diet Coke, so this will be changing

soon. You will find Stevia popping up in alot of things. Stevia is a natural

(plant source) sweetener...you just have to be careful what company you buy it

from, because they use various means of producing the sweetener. Don't want

anything processed chemically.

Amy Hodge    

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  • 2 weeks later...

Dr. Holli,

I have always wondered about this. I get the most awful, pounding,

splitting headaches when I consume aspartame. One can of diet soda is

enough to send me to the couch for the rest of the day, and if I

should bend over with this headache, well, I have considered that

decapitation might be less painful! This happens to at least three

other people I know, as well. Are we all phenylketonurics, or simply

sensitive to the substance? Not that naming the problem would change

it, I just thought that if it is such a rare condition, how do I know

so many people with the same problem?

Thanks,

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Hi ,

I use to drink diet pop until one day I collapsed, and had been having awful

night tremors. I finally put it together that it was the phenylalanine.

Now if I drink anything with a sugar substitute I get tremors all night. I also

have the same problems if I get any MSG in my food.

I read an article that stated phenylalanine causes nerve damage... we should all

stay away from it!

Kay~Beautiful Oregon Coast

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Hi ,

After the standard disclaimer that I have never physically examined

you and only have the brief information you've given me -- what you

describe sounds like a classic migraine. Migraines can have many

triggers and can be quite individual. I have heard anecdotally about

aspartame being a trigger for some - have not heard of it being

linked to phenylalanine, but that doesn't mean it can't be.

You most certainly are not a phenylketonuric. People with this

disease must be on a very strict diet, completely cutting out

phenylalanine from birth or they will be severely developementally

retarted. You couldn't possibly make it to adulthood with a typical

diet without severe mental defecits. Another physical characteristic

is very fine, brittle, blond hair. It's common to all PKU pts. (I

don't know what you look like, but that might help you). Migraines,

on the other hand are excedingly common. I get them too, my trigger

is hormonal -- a little harder to avoid! Luckily, mine are very

responsive to Excedrin Migraine formula. Not everyone is so lucky.

It sounds like the potential for nerve damage from phenylalanine and

the general warnings against aspartame as well as a probable

migraine trigger for you all point to avoiding this artificial

substitute for good old sugar. Consume the sugar in moderation and

all should be fine!

On a gut level, with my moderate knowlege of science and physiology,

I tend to avoid all the " fat-free, sugar-free, food-free "

substitutes that claim to make us more healthy. In my opinion the

healthiest diets are cooked at home from easily recognizable

ingredients. The more the syllables in the ingredient list, the less

healthy. Have you ever microwaved that fat free cheese? It becomes

permanantly polymerized to the plate. Wonder what it does inside

your body?? That's just personal opinion, take it for what it's

worth!

Holli

now in Tarzana, CA (on the site of the former Tarzan Ranch)

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