Guest guest Posted July 26, 2009 Report Share Posted July 26, 2009 I suggest that you look up Stachybotrys and its mycotoxins at wikipedia. Also look up T-2 toxin at wikipedia. Wikipedia does a good review for the layman. Whomever is pushing the T-2Toxin test must demonstrate to the public that the laboratory is registered with CLIA. That the laboratory has passed all CLIA inspections with respect to the validation of the test. The T-2 test kit was developed to detect T-2 toxins in animal feed, not human urine. I read in a post that the pusher of this test claims it was developed by the military. The military is not CLIA nor is it the FDA. FDA regulates human testing via CLIA. I am tired of wasting my energy on this matter. If you wish to use test that will not be accepted in the court of law and does not tesst for the mycotoxins produced by Stachybotrys then waste your money, but not my time. Jack D. Thrasher, Ph.D. Toxicologist/Immunotoxicologist/Fetaltoxicologist www.drthrasher.org toxicologist1@... Off: 916-745-4703 Cell: 575-937-1150 L. Crawley, M.ED., LADC Trauma Specialist sandracrawley@... 916-745-4703 - Off 775-309-3994 - Cell This message and any attachments forwarded with it is to be considered privileged and confidential. The forwarding or redistribution of this message (and any attachments) without my prior written consent is strictly prohibited and may violate privacy laws. Once the intended purpose of this message has been served, please destroy the original message contents. If you have received this message in error, please reply immediately to advise the sender of the miscommunication and then delete the message and any copies you have printed. Thank you in advance for your compliance. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2009 Report Share Posted July 26, 2009 Here is website on T-2- Test kits. They were developed for testing of T-1 Toxin in foods not human urine. Also, T-1 Toxin studied by the Army and yellow rain is produced by Fusarium, not Stachybotrys http://www.vicam.com/aw/myco/?gclid=COjn9PLW85sCFQ6jagodzDAm-g Jack D. Thrasher, Ph.D. Toxicologist/Immunotoxicologist/Fetaltoxicologist www.drthrasher.org toxicologist1@... Off: 916-745-4703 Cell: 575-937-1150 L. Crawley, M.ED., LADC Trauma Specialist sandracrawley@... 916-745-4703 - Off 775-309-3994 - Cell This message and any attachments forwarded with it is to be considered privileged and confidential. The forwarding or redistribution of this message (and any attachments) without my prior written consent is strictly prohibited and may violate privacy laws. Once the intended purpose of this message has been served, please destroy the original message contents. If you have received this message in error, please reply immediately to advise the sender of the miscommunication and then delete the message and any copies you have printed. Thank you in advance for your compliance. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2009 Report Share Posted July 30, 2009 --- Carl, I know your post was for but this is the first time I have read that tricothecine can be from food. I NEVER knew that certain foods can cause tricothecine to show up in the urine. Are these foods the typical yeasty or high sugar foods like bread, pasties etc? Can Candida in the body cause a high triocthecine level? Thank you. Diane In , " Carl E. Grimes " <grimes@...> wrote: > > > Without getting into the specifics of your testing, we must be clear > about what various tests can and cannot do. Your question is > assumes a direct connection from Stachybotrys to a mycotoxin in > the body. Actually, it also assumes that a sample was collected > and analyzed which showed Stachybotrys and you were exposed > to the Stachy and it produced Tricothesines in your body and that > is what what made you ill. But there are a lot of assumptions > here. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2009 Report Share Posted July 30, 2009 Diane, I may have mis-spoke with that illustrative point. I should have used the word " mycotoxin " instead of listing a specific mycotoxin such trichothecine. Sorry if I confused any of you. Carl Grimes Healthy Habitats LLC ----- > > > --- > Carl, I know your post was for but this is the first time I have read that tricothecine can be from food. I > NEVER knew that certain foods can cause tricothecine to show up in the urine. Are these foods the typical > yeasty or high sugar foods like bread, pasties etc? Can Candida in the body cause a high triocthecine level? > Thank you. Diane > > In groups (DOT) com, " Carl E. Grimes " <grimes@...> wrote: > > > > > > Without getting into the specifics of your testing, we must be clear > > about what various tests can and cannot do. Your question is > > assumes a direct connection from Stachybotrys to a mycotoxin in > > the body. Actually, it also assumes that a sample was collected > > and analyzed which showed Stachybotrys and you were exposed > > to the Stachy and it produced Tricothesines in your body and that > > is what what made you ill. But there are a lot of assumptions > > here. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 31, 2009 Report Share Posted July 31, 2009 I must be dead in the head, I missed that. GREAT QUESTION Dianne. I will wait for the answer but sure makes alot of sence. Candida is a b*%#h. > > > Without getting into the specifics of your testing, we must be clear > about what various tests can and cannot do. Your question is > assumes a direct connection from Stachybotrys to a mycotoxin in > the body. Actually, it also assumes that a sample was collected > and analyzed which showed Stachybotrys and you were exposed > to the Stachy and it produced Tricothesines in your body and that > is what what made you ill. But there are a lot of assumptions > here. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 31, 2009 Report Share Posted July 31, 2009 Carl, I wasnt confused till I just read this...Ha ha > > > > > > Without getting into the specifics of your testing, we must be clear > > about what various tests can and cannot do. Your question is > > assumes a direct connection from Stachybotrys to a mycotoxin in > > the body. Actually, it also assumes that a sample was collected > > and analyzed which showed Stachybotrys and you were exposed > > to the Stachy and it produced Tricothesines in your body and that > > is what what made you ill. But there are a lot of assumptions > > here. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 1, 2009 Report Share Posted August 1, 2009 OT: Carl, Is there any equipment that measures dryer exhaust outside. I live on the third floor and the washers are down on the ground floor, A girl next balcony over has a washer but most people use the washers downstairs. I thought being on a hight level I would be away from the exhaust. I have tried living on every level through the years at differt complexes. Sometimes the fumes are so strong I can't believe this is allowed. One woman uses pinsole to wash. I have always wanted to get some legislator to do something about putting dryer exhaust vents in new construction away from windows. I don't understand why nothing is ever done about this issue. Just wondering if there is some way to measure the chemicals? Thanks, > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 1, 2009 Report Share Posted August 1, 2009 Chris: As Carl knows, there is much written on the subject of cereal grains and trichothecenes. You can do a Google search and find the following: Foroud NA, Eudes F. 2009 Trichothecens in Cereal Grains. Int J Mol Sci 10:147-73. National Research Council. 1993 Protection against trichothecene mycotoxins. In the treatise by the NRC, 1993 The species and genera of molds that produce trichothecenes are discussed beginning on page 21. The trichothecenes are of two basic types: simple and macrocyclic. The simple ones are characterized by Fusarium species, e.g. -T-2 toxin, while the macrocyclics are produced by Stachybotrys (Saratoxins, Roridins, etc.). The molds that produce trichothecenes are: Fusarium, Acremonium, Trichoderma, Trichothecium, Myrothecium, Stachybotrys and possibly Cylindrocarpon. If you look at the paper by Furoud and Eudes you will find that the trichothecenes found in cereal grains are mainly from Fusarium species, which means simple trichothecenes, e.g. T-2 toxins. The urine test detects mainly macrocyclic trichothecenes which can be produced by Trichoderma viridae, Stachybotrys and Myrothecium. Finally, Candida sp do not produce trichothecenes. The danger of Candida species comes from gliotoxin, which is also produced by Aspergillus flavus, niger, terreus and fumigatus. Gliotoxn has been detected in the sera of cancer patients with Aspergillosis in infections resulting from these four species. You can find the these papers on Gliotoxin by doing an entrez pubmed search for RE gliotoxin aspergillosis cancer patients. Finally, I would like to point out once again regarding fine particles and the indoor environment. There is a fairly recent paper by Reponen et al, 2007 (do a google search) for Reponen T. Fungal fragments in mold houses, Atmos Environ 2007 41:8140-49) shows that fine fungal fragements less than the size of spores are predominant and up to 500 times more concentrated than fungal spores in indoor environments. Dr. Reponen adequately reviews the literature on this subject which includes the papers by Brasel and Gorny. These fine particles contain mycotoxins and other toxins produced by molds and bacteria. You need to educate yourself in order to understand what is going on in the ibiocomplexity of the ndoor environment resulting from microbial growth (molds and bacteria). Jack D. Thrasher, Ph.D. Toxicologist/Immunotoxicologist/Fetaltoxicologist www.drthrasher.org toxicologist1@... Off: 916-745-4703 Cell: 575-937-1150 L. Crawley, M.ED., LADC Trauma Specialist sandracrawley@... 916-745-4703 - Off 775-309-3994 - Cell This message and any attachments forwarded with it is to be considered privileged and confidential. The forwarding or redistribution of this message (and any attachments) without my prior written consent is strictly prohibited and may violate privacy laws. Once the intended purpose of this message has been served, please destroy the original message contents. If you have received this message in error, please reply immediately to advise the sender of the miscommunication and then delete the message and any copies you have printed. Thank you in advance for your compliance. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 1, 2009 Report Share Posted August 1, 2009 Dr Thrasher, A quick addition for the group about the very small partical sizes you mentioned. One way to measure exposure is by particle count. As the spores and growth structures fragment the number of particles increase. But the total weight (mass), another way of measuring potential exposure, of mold spores and fragments in the air stays the same. discussed at the Orlando conference in April another way in which exposure can increase. Not only do the number of particles increase, but the surface area of the particles increase as they get smaller. Which means the exposure can increase even more than just from more particles even though the total mass remains the same. This is not considered in traditional toxicological or epidemiological studies. Carl Grimes Healthy Habitats LLC ----- Chris: As Carl knows, there is much written on the subject of cereal grains and trichothecenes. You can do a Google search and find the following: Foroud NA, Eudes F. 2009 Trichothecens in Cereal Grains. Int J Mol Sci 10:147-73. National Research Council. 1993 Protection against trichothecene mycotoxins. In the treatise by the NRC, 1993 The species and genera of molds that produce trichothecenes are discussed beginning on page 21. The trichothecenes are of two basic types: simple and macrocyclic. The simple ones are characterized by Fusarium species, e.g. -T-2 toxin, while the macrocyclics are produced by Stachybotrys (Saratoxins, Roridins, etc.). The molds that produce trichothecenes are: Fusarium, Acremonium, Trichoderma, Trichothecium, Myrothecium, Stachybotrys and possibly Cylindrocarpon. If you look at the paper by Furoud and Eudes you will find that the trichothecenes found in cereal grains are mainly from Fusarium species, which means simple trichothecenes, e.g. T-2 toxins. The urine test detects mainly macrocyclic trichothecenes which can be produced by Trichoderma viridae, Stachybotrys and Myrothecium. Finally, Candida sp do not produce trichothecenes. The danger of Candida species comes from gliotoxin, which is also produced by Aspergillus flavus, niger, terreus and fumigatus. Gliotoxn has been detected in the sera of cancer patients with Aspergillosis in infections resulting from these four species. You can find the these papers on Gliotoxin by doing an entrez pubmed search for RE gliotoxin aspergillosis cancer patients. Finally, I would like to point out once again regarding fine particles and the indoor environment. There is a fairly recent paper by Reponen et al, 2007 (do a google search) for Reponen T. Fungal fragments in mold houses, Atmos Environ 2007 41:8140-49) shows that fine fungal fragements less than the size of spores are predominant and up to 500 times more concentrated than fungal spores in indoor environments. Dr. Reponen adequately reviews the literature on this subject which includes the papers by Brasel and Gorny. These fine particles contain mycotoxins and other toxins produced by molds and bacteria. You need to educate yourself in order to understand what is going on in the ibiocomplexity of the ndoor environment resulting from microbial growth (molds and bacteria). Jack D. Thrasher, Ph.D. Toxicologist/Immunotoxicologist/Fetaltoxicologist www.drthrasher.org toxicologist1@... Off: 916-745-4703 Cell: 575-937-1150 L. Crawley, M.ED., LADC Trauma Specialist sandracrawley@... 916-745-4703 - Off 775-309-3994 - Cell This message and any attachments forwarded with it is to be considered privileged and confidential. The forwarding or redistribution of this message (and any attachments) without my prior written consent is strictly prohibited and may violate privacy laws. Once the intended purpose of this message has been served, please destroy the original message contents. If you have received this message in error, please reply immediately to advise the sender of the miscommunication and then delete the message and any copies you have printed. Thank you in advance for your compliance. Quote Link to comment Share on other sites More sharing options...
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