Re: New Basic Mold Research

[Guest guest]

O dont think this is saying that people wont get sick from AF, sounds like it's

saying that this is a way that AF can colonize in the lungs and later cause

havic.

>

>  This NEW research explains why MOST people DON'T get sick from mold. Maybe

some researchers can build upon this discovery, to figure out why WE DO get

sick from mold. When you click on the link, you can save and print out the free

summary PDF of this article. You may have to register first, with the science

journal.

[Guest guest]

gee,after thinking about this, this just might explain what I was talking about

in a recent post about haveing 2 different effects with my lungs. the

MCS-reactive airways and the nin-reactiveairwaybut the felling if something

causeing what fells like a infection in my lungs. this being the felling of

infection. those AF spores sneaking right in there without causeing me to react

and cough them back out. so they can do their thing in my lungs. what I dont

know is weather this would be considered allergic allpergillus,or

aspergilliosis,

or invasive aspergilliosis. only thing is, os that their oppertunity comes

pretty quickly.

>

>

>  This NEW research explains why MOST people DON'T get sick from mold.

[Guest guest]

You missed the whole point of authors. It is in the last paragraph:

" The avoidance of immune activation has benefits for both the fungus and the

host. For the host it prevents chronic activation of the immune system in

response to the constant inhalation of spores, whereas for the fungus it

prevents rapid elimination, allowing the cells to survive in the lungs of the

host until an opportunity to germinate and proliferate arises. "

There multiple other factors in damp indoor spaces that create health problems

for people exposed to these environments: multiple species of molds and

potentially pathogenci bacteria, mycotoxins, hemolysins, extracellular proteins

(antigens) that molds release to digest the substrate, endotoxins, glucans,

glactomannans, fine particles, ulrafine particles, etc. etc. Also, if you have

been put on corticosteriods because of upper and lower respiratory inflammation

you are at increased risk for invasive molds, e.g. aspergillosis.

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

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[Guest guest]

Dr Thrasher, You said one is at extra risk of invasive aspergillus infection if

you are on corticosteriods. Is that because corticosterioids suppress the

immune system? I have never understood why steriod are Rxed so much. Thanks

--- In , " Jack Thrasher, Ph.D. " <toxicologist1@...>

wrote:

>

>if you have been put on corticosteriods because of upper and lower respiratory

inflammation you are at increased risk for invasive molds, e.g. aspergillosis.

>

>

> Jack-Dwayne: Thrasher, Ph.D.

> Toxicologist/Immunotoxicologist/Fetaltoxicologist

> www.drthrasher.org

> toxicologist1@...

> Off: 916-745-4703

> Cell: 575-937-1150

>

>

> L. Crawley, M.ED., LADC

> Trauma Specialist

> sandracrawley@...

> 916-745-4703 - Off

> 775-309-3994 - Cell

>

>

>

>

> This message and any attachments forwarded with it is to be considered

privileged and confidential. The forwarding or redistribution of this message

(and any attachments) without my prior written consent is strictly prohibited

and may violate privacy laws. Once the intended purpose of this message has been

served, please destroy the original message contents. If you have received this

message in error, please reply immediately to advise the sender of the

miscommunication and then delete the message and any copies you have printed.

Thank you in advance for your compliance.

>

>

>

>

[Guest guest]

I do not understand either.  As I know a person with Hypersensitivity

Pnuemonitis from mold who was placed on prednisone.

 

Is that appropriate treatment ??

God Bless !!

dragonflymcs

Mayleen

________________________________

From: Barb W <barb1283@...>

Sent: Sunday, September 27, 2009 10:27:31 AM

Subject: [] Re: New Basic Mold Research

 

Dr Thrasher, You said one is at extra risk of invasive aspergillus infection if

you are on corticosteriods. Is that because corticosterioids suppress the immune

system? I have never understood why steriod are Rxed so much. Thanks

[Guest guest]

Corticosteroids do not affect the ability of macrohages to take in spore by

phagocytosis. Therefore, the macrophages can take in spores and/or other debri.

The steriods prevent the macrophages from releasing free radicals amd ensymes

that doing the killing. Therefore, the spores are not killed amd cam be carried

to other organs of the body.

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

This message and any attachments forwarded with it is to be considered

privileged and confidential. The forwarding or redistribution of this message

(and any attachments) without my prior written consent is strictly prohibited

and may violate privacy laws. Once the intended purpose of this message has been

served, please destroy the original message contents. If you have received this

message in error, please reply immediately to advise the sender of the

miscommunication and then delete the message and any copies you have printed.

Thank you in advance for your compliance.

[Guest guest]

Thank for this Dr Thrasher, now I can explain why I cannot have these in a way

they can undertsand with an explanation a Dr (who knows nothing of mold and

mycotoxins )  would accept rather than I cannot which they take as a refusal not

based on anything legitimate.

 

God Bless !!

dragonflymcs

Mayleen

________________________________

From: " Jack Thrasher, Ph.D. " <toxicologist1@...>

Sent: Sunday, September 27, 2009 11:39:47 PM

Subject: [] Re: New Basic Mold Research

 

Corticosteroids do not affect the ability of macrohages to take in spore by

[Guest guest]

Corticosteroids suppress the production of free radicals and enzymes of

macrophages that kill microorganisms. The macrophages can take in the

microorganisms by phagocytosis, but are unable to kill them. Thus, the

macrophages can carry viable organisms to other organs.

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

This message and any attachments forwarded with it is to be considered

privileged and confidential. The forwarding or redistribution of this message

(and any attachments) without my prior written consent is strictly prohibited

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served, please destroy the original message contents. If you have received this

message in error, please reply immediately to advise the sender of the

miscommunication and then delete the message and any copies you have printed.

Thank you in advance for your compliance.

[Guest guest]

Steroids can be used for short period of times, e.g. less than two weeks.

Chronic usage of 2 weeks or more is associated with increased risk.

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

This message and any attachments forwarded with it is to be considered

privileged and confidential. The forwarding or redistribution of this message

(and any attachments) without my prior written consent is strictly prohibited

and may violate privacy laws. Once the intended purpose of this message has been

served, please destroy the original message contents. If you have received this

message in error, please reply immediately to advise the sender of the

miscommunication and then delete the message and any copies you have printed.

Thank you in advance for your compliance.

[Guest guest]

Does a person's lung just collect pathogens and particles your whole life and

then when we get weak or old, they can infect? Are our lungs able to get rid of

anything or do they just keep filling up with debris??? Does anyone know?

--- In , " Jack Thrasher, Ph.D. " <toxicologist1@...>

wrote:

>

>allowing the cells to survive in the lungs of the host until an opportunity to

germinate and proliferate arises. "

>