Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 : This sounds like its out of my league too, but without hearing how she is or why you are concerned about this right now I am really in the dark. What led you to do the strep tests? Are seizures increasing? (I have not heard of a connection between strep infection and seizures, have you?) Any sore throat? Fever? Has she been around the relative (daughter's nephew) while he had an active strep infection lately? I know of no way to diagnose CNS strep other than to do a culture of cerebro-spinal fluid, but would not want to do a spurious spinal tap unless high fever or some striking clinical evidence indicated a brain infection. Elevated CRP is definitely related to inflammation, but non-specific, so that does not help much. Doing a throat culture without a sore throat would probably be an exercise in futility, and doing a stool analysis would probably be the same without some stool symptoms like diarrhea or constipation. I prefer IM penicillin for PANDAS treatment for kids with autism who have fragile gi systems and strong vulnerability to gut pathogen invasion - I don't know whether your daughter would be in this category. I think I would need more info about her symptoms and status generally to say any more. Dr. JM --- mbrookh wrote: > My daughter's ASO just came back 103.5[0-200] and > Anti-DNase B Strep > 1:340[adult<1:85]. ASO in the past has been lower. > DNase has never > been done. In prior years CRP has been elevated when > my daughter > seemed 'sick' to me - no symptoms that were > objective like fever, > elevated WBC, lethargy etc. ASO and anti-DNase were > performed because > 1)there's family history of strep problems[rheumatic > fever] and 2)my > daughter's nephew, now 8, has strep several times > per year with his > only symptom being OCD. He was on the spectrum as a > toddler but is > recovered except for this recurring strep issue. My > questions - can > the CRP also indicate this strep problem? Would > cultures be of > benefit? Where to culture - if the strep is deep in > the bowel do > throat/nasal cultures grow it? Do such cultures need > extended growth > time for chronic problems? If this has been a long > term problem[she > is 23 now and was ALWAYS better on penicillin the > few times she had > it as a as a toddler] what type of treatment could > be beneficial? If > penicillin, oral or IM? How long? Does > ANti-DNase/ASO go down quickly > with treatment? Does the strep/biofilm theory relate > here - she has > the elevated oxalates and hippuric acid on OAT. If > so, does treatment > with penicillin do much if the strep colonies are > growing in a > protected environment? does it need a longer course > to be effective? > Can I assume that a strep problem relates to seizure > activity? Is CNS > strep diagnosable independent of these blood levels? > Sorry about all > the ? I'm out of my league. Thanks, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 I know another mom on another board with a PANDAS kid, us with our and my aspie adult friend all got ours gone with OLE. we all did 2 rounds at least some of us 3 rounds of antibotics with out results or lowering of results. we are alleric to penicillian so it was never an option. we always see OCD increase and loose of potty training when we are suspect Recovering from Autism is a marathon NOT a sprint, but FULLY possible! Read more about it on my Blogs at http://www.myspace.com/christelking Re: re: strep : This sounds like its out of my league too, but without hearing how she is or why you are concerned about this right now I am really in the dark. What led you to do the strep tests? Are seizures increasing? (I have not heard of a connection between strep infection and seizures, have you?) Any sore throat? Fever? Has she been around the relative (daughter's nephew) while he had an active strep infection lately? I know of no way to diagnose CNS strep other than to do a culture of cerebro-spinal fluid, but would not want to do a spurious spinal tap unless high fever or some striking clinical evidence indicated a brain infection. Elevated CRP is definitely related to inflammation, but non-specific, so that does not help much. Doing a throat culture without a sore throat would probably be an exercise in futility, and doing a stool analysis would probably be the same without some stool symptoms like diarrhea or constipation. I prefer IM penicillin for PANDAS treatment for kids with autism who have fragile gi systems and strong vulnerability to gut pathogen invasion - I don't know whether your daughter would be in this category. I think I would need more info about her symptoms and status generally to say any more. Dr. JM --- mbrookh wrote: > My daughter's ASO just came back 103.5[0-200] and > Anti-DNase B Strep > 1:340[adult<1:85]. ASO in the past has been lower. > DNase has never > been done. In prior years CRP has been elevated when > my daughter > seemed 'sick' to me - no symptoms that were > objective like fever, > elevated WBC, lethargy etc. ASO and anti-DNase were > performed because > 1)there's family history of strep problems[rheumatic > fever] and 2)my > daughter's nephew, now 8, has strep several times > per year with his > only symptom being OCD. He was on the spectrum as a > toddler but is > recovered except for this recurring strep issue. My > questions - can > the CRP also indicate this strep problem? Would > cultures be of > benefit? Where to culture - if the strep is deep in > the bowel do > throat/nasal cultures grow it? Do such cultures need > extended growth > time for chronic problems? If this has been a long > term problem[she > is 23 now and was ALWAYS better on penicillin the > few times she had > it as a as a toddler] what type of treatment could > be beneficial? If > penicillin, oral or IM? How long? Does > ANti-DNase/ASO go down quickly > with treatment? Does the strep/biofilm theory relate > here - she has > the elevated oxalates and hippuric acid on OAT. If > so, does treatment > with penicillin do much if the strep colonies are > growing in a > protected environment? does it need a longer course > to be effective? > Can I assume that a strep problem relates to seizure > activity? Is CNS > strep diagnosable independent of these blood levels? > Sorry about all > the ? I'm out of my league. Thanks, > > ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2008 Report Share Posted January 3, 2008 you need to retest the titers off the meds and see if it's still there, regular antibotics never helped ours we had to do OLE Recovering from Autism is a marathon NOT a sprint, but FULLY possible! Read more about it on my Blogs at http://www.myspace.com/christelking Re: strep This fall my son started having tics, and because of his history of regression after strep, we suspected that we had missed a strep infection. We took blood for titers, and then started a month long course of zithromax. The titers (ASO and dNase) both came back negative. After a week on the antibiotic, the frequency of tics was down about 50%,and then after 3 weeks, the tics were completely gone. Now a week and a half after stopping the antibiotic, the tics are back. Not sure what to think about this. We would like to restart the antibiotics (penicillin shots this time). Is the antibiotic really helping? I'm surprised the titers were negative. Thanks, > > > My daughter's ASO just came back 103.5[0-200] and > > Anti-DNase B Strep > > 1:340[adult<1:85]. ASO in the past has been lower. > > DNase has never > > been done. In prior years CRP has been elevated when > > my daughter > > seemed 'sick' to me - no symptoms that were > > objective like fever, > > elevated WBC, lethargy etc. ASO and anti-DNase were > > performed because > > 1)there's family history of strep problems[rheumatic > > fever] and 2)my > > daughter's nephew, now 8, has strep several times > > per year with his > > only symptom being OCD. He was on the spectrum as a > > toddler but is > > recovered except for this recurring strep issue. My > > questions - can > > the CRP also indicate this strep problem? Would > > cultures be of > > benefit? Where to culture - if the strep is deep in > > the bowel do > > throat/nasal cultures grow it? Do such cultures need > > extended growth > > time for chronic problems? If this has been a long > > term problem[she > > is 23 now and was ALWAYS better on penicillin the > > few times she had > > it as a as a toddler] what type of treatment could > > be beneficial? If > > penicillin, oral or IM? How long? Does > > ANti-DNase/ASO go down quickly > > with treatment? Does the strep/biofilm theory relate > > here - she has > > the elevated oxalates and hippuric acid on OAT. If > > so, does treatment > > with penicillin do much if the strep colonies are > > growing in a > > protected environment? does it need a longer course > > to be effective? > > Can I assume that a strep problem relates to seizure > > activity? Is CNS > > strep diagnosable independent of these blood levels? > > Sorry about all > > the ? I'm out of my league. Thanks, > > > > > ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2008 Report Share Posted January 3, 2008 you might be better having numbers rather then negitive possitive. so you can see them go up and down. negitive just means in range but if it's close to the edge that is important to know Recovering from Autism is a marathon NOT a sprint, but FULLY possible! Read more about it on my Blogs at http://www.myspace.com/christelking Re: strep I'm assuming his titers are still negative, since they were negative before we started the antibiotics. > > > > > My daughter's ASO just came back 103.5[0-200] and > > > Anti-DNase B Strep > > > 1:340[adult<1:85]. ASO in the past has been lower. > > > DNase has never > > > been done. In prior years CRP has been elevated when > > > my daughter > > > seemed 'sick' to me - no symptoms that were > > > objective like fever, > > > elevated WBC, lethargy etc. ASO and anti-DNase were > > > performed because > > > 1)there's family history of strep problems[rheumatic > > > fever] and 2)my > > > daughter's nephew, now 8, has strep several times > > > per year with his > > > only symptom being OCD. He was on the spectrum as a > > > toddler but is > > > recovered except for this recurring strep issue. My > > > questions - can > > > the CRP also indicate this strep problem? Would > > > cultures be of > > > benefit? Where to culture - if the strep is deep in > > > the bowel do > > > throat/nasal cultures grow it? Do such cultures need > > > extended growth > > > time for chronic problems? If this has been a long > > > term problem[she > > > is 23 now and was ALWAYS better on penicillin the > > > few times she had > > > it as a as a toddler] what type of treatment could > > > be beneficial? If > > > penicillin, oral or IM? How long? Does > > > ANti-DNase/ASO go down quickly > > > with treatment? Does the strep/biofilm theory relate > > > here - she has > > > the elevated oxalates and hippuric acid on OAT. If > > > so, does treatment > > > with penicillin do much if the strep colonies are > > > growing in a > > > protected environment? does it need a longer course > > > to be effective? > > > Can I assume that a strep problem relates to seizure > > > activity? Is CNS > > > strep diagnosable independent of these blood levels? > > > Sorry about all > > > the ? I'm out of my league. Thanks, > > > > > > > > > > > > > > > ---------------------------------------------------------- > > > No virus found in this incoming message. > Checked by AVG Free Edition. > Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2008 Report Share Posted January 4, 2008 it may have been flaring viral issues, or stirring up yeast as it's an antibacterial and antiviral Recovering from Autism is a marathon NOT a sprint, but FULLY possible! Read more about it on my Blogs at http://www.myspace.com/christelking Re: strep I've tried OLE in the past and it produced such nasty side effects - behavior that was 8-9 on a 10 point irritability scale. OLE may have been downing the critters and I didn't realize it! Did you titrate the dose up? What did you use as adult dose? how long? Thanks, > > > > > My daughter's ASO just came back 103.5[0-200] and > > > Anti-DNase B Strep > > > 1:340[adult<1:85]. ASO in the past has been lower. > > > DNase has never > > > been done. In prior years CRP has been elevated when > > > my daughter > > > seemed 'sick' to me - no symptoms that were > > > objective like fever, > > > elevated WBC, lethargy etc. ASO and anti-DNase were > > > performed because > > > 1)there's family history of strep problems[rheumatic > > > fever] and 2)my > > > daughter's nephew, now 8, has strep several times > > > per year with his > > > only symptom being OCD. He was on the spectrum as a > > > toddler but is > > > recovered except for this recurring strep issue. My > > > questions - can > > > the CRP also indicate this strep problem? Would > > > cultures be of > > > benefit? Where to culture - if the strep is deep in > > > the bowel do > > > throat/nasal cultures grow it? Do such cultures need > > > extended growth > > > time for chronic problems? If this has been a long > > > term problem[she > > > is 23 now and was ALWAYS better on penicillin the > > > few times she had > > > it as a as a toddler] what type of treatment could > > > be beneficial? If > > > penicillin, oral or IM? How long? Does > > > ANti-DNase/ASO go down quickly > > > with treatment? Does the strep/biofilm theory relate > > > here - she has > > > the elevated oxalates and hippuric acid on OAT. If > > > so, does treatment > > > with penicillin do much if the strep colonies are > > > growing in a > > > protected environment? does it need a longer course > > > to be effective? > > > Can I assume that a strep problem relates to seizure > > > activity? Is CNS > > > strep diagnosable independent of these blood levels? > > > Sorry about all > > > the ? I'm out of my league. Thanks, > > > > > > > > > > > > > > > ---------------------------------------------------------- ---------- > > > No virus found in this incoming message. > Checked by AVG Free Edition. > Version: 7.5.516 / Virus Database: 269.17.13/1207 - Release Date: 1/2/2008 11:29 AM > > > Quote Link to comment Share on other sites More sharing options...
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