Re[2]: Re: CONSORTIUM OF RESEARCHERS DISCOVER RETROVIRAL LINK TO CHRONIC FATIGUE SYNDROME

[Guest guest]

Quite some time ago, I discussed retroviruses with the leading global

veterinary virologist in relation to bird diseases. He felt that the

retrovirus is secondary to any major virus or disease in a bird

because of the compromised immune condition. Who knows?

Barth

www.presenting.net/sbs/sbs.html

SUBMIT YOUR DOCTOR: www.presenting.net/sbs/molddoctors.html

---

CEG> bell,

CEG> For a long time I've believed that part of what can happen is that

CEG> we already have a virus, bacteria, or fungi inside our body. But it

CEG> doesn't grow (infect) because the conditions aren't quite right. It's

CEG> why we don't get the flu today or tomorrow but do the next day.

CEG> Or not at all. The 'germs' are certainly plentiful. But they don't

CEG> infect.

CEG> So the virus being discussed may already be present but can't

CEG> grow until the environment of our body changes from being

CEG> overwhelmed with mold or bacteria or filth caused my moisture or

CEG> chemicals or any of a thousand other events hits a " trigger " point.

CEG> Carl Grimes

CEG> Healthy Habitats LLC

CEG> -----

CEG> Thank you for this link and info. I suffer from chronic fatigue but wonder

where it came about. I did not have it until after my mold exposure... so where

would this virus have come from???

CEG> --- In groups (DOT) com, a Townsend <kmtown2003@...>

wrote:

>>

>> Great news, bad news, Yeah, CFS patients are no longer crazy or lazy. They

are sick.

>> bad news, they are only looking at one pathogen.. and where did they pick up

this virus?

>>

>>

>> U.S. Department of Health and Human Services

>> NATIONAL

>> INSTITUTES OF HEALTH NIH News

>> National Cancer Institute (NCI) <http://www.nci. nih.gov/>

>> Embargoed for

>> Release: Thursday, October 8, 2009, 2 p.m. EDT

>>

>> CONTACTS:

>> NCI Office

>> of Media Relations, 301-496-6641, <e-mail: ncipressofficers@ mail.nih. gov>

>>

>>

>> Whittemore Institute, ie Vigil, 775-336-4555,

>> <e-mail:ie. vigil@rrpartners .com>

>>

>> Cleveland Clinic Corp.

>> Communications, F. Pruce, 216-445-7452,

>> <e-mail:prucem@ ccf.org>

>>

>> CONSORTIUM OF RESEARCHERS DISCOVER

>> RETROVIRAL LINK TO CHRONIC FATIGUE SYNDROME

>>

>> Scientists have discovered a

>> potential retroviral link to chronic fatigue syndrome, known as CFS, a

>> debilitating disease that affects millions of people in the United States.

>> Researchers from the Whittemore Institute (WPI), located at the

>> University of Nevada, Reno, the National Cancer Institute (NCI), part of the

>> National Institutes of Health, and the Cleveland Clinic, report this finding

>> online Oct. 8, 2009, issue of Science.

>>

>> " We now have evidence that a

>> retrovirus named XMRV is frequently present in the blood of patients with

CFS.

>> This discovery could be a major step in the discovery of vital treatment

options

>> for millions of patients, " said Judy Mikovits, Ph.D., director of research

for

>> WPI and leader of the team that discovered this association. Researchers

>> cautioned however, that this finding shows there is an association between

XMRV

>> and CFS but does not prove that XMRV causes CFS.

>>

>> The scientists provide

>> a new hypothesis for a retrovirus link with CFS. The virus, XMRV, was first

>> identified by H. Silverman, Ph.D., professor in the Department of

Cancer

>> Biology at the Cleveland Clinic Lerner Research Institute, in men who had a

>> specific immune system defect that reduced their ability to fight viral

>> infections.

>>

>> " The discovery of XMRV in two major diseases, prostate

>> cancer and now chronic fatigue syndrome, is very exciting. If

>> cause-and-effect is established, there would be a new opportunity for

prevention

>> and treatment of these diseases, " said Silverman, a co-author on the CFS

paper.

>>

>>

>> Commonality of an immune system defect in patients with CFS and prostate

>> cancer led researchers to look for the virus in their blood samples. In this

>> study, WPI scientists identified XMRV in the blood of 68 of 101 (67 percent)

CFS

>> patients. In contrast, they found that eight of 218 healthy people (3.7

>> percent) contained XMRV DNA. The research team not only found that blood

cells

>> contained XMRV but also expressed XMRV proteins at high levels and produced

>> infectious viral particles. A clinically validated test to detect XMRV

>> antibodies in patients' plasma is currently under development.

>>

>> These

>> results were also supported by the observation of retrovirus particles in

>> patient samples when examined using transmission electron microscopy. The

data

>> demonstrate the first direct isolation of infectious XMRV from humans.

>>

>>

>>

>> " These compelling data allow the development of a hypothesis

>> concerning a cause of this complex and misunderstood disease, since

retroviruses

>> are a known cause of neurodegenerative diseases and cancer in man, " said

Francis

>> Ruscetti, Ph.D., Laboratory of Experimental Immunology, NCI.

>>

>>

>> Retroviruses like XMRV have also been shown to activate a number of

>> other latent viruses. This could explain why so many different viruses, such

as

>> Epstein-Barr virus, which was causally linked to Burkitt's and other

lymphomas

>> in the 1970s, have been associated with CFS. It is important to note that

>> retroviruses, like XMRV, are not airborne.

>>

>> " The scientific

>> evidence that a retrovirus is implicated in CFS opens a new world of

>> possibilities for so many people, " said Annette Whittemore, founder and

>> president of WPI and mother of a CFS patient. " Scientists can now begin

>> the important work of translating this discovery into medical care for

>> individuals with XMRV related diseases. "

>>

>> Dan , M.D., medical

>> director of WPI added, " Patients with CFS deal with a myriad of health issues

as

>> their quality of life declines. I'm excited about the possibility of

>> providing patients, who are positive for XMRV, a definitive diagnosis, and

>> hopefully very soon, a range of effective treatments options. "

>>

>> The

>> Whittemore Institute for Neuro Immune Disease exists to bring

>> discovery, knowledge, and effective treatments to patients with illnesses

that

>> are caused by acquired dysregulation of both the immune system and the

nervous

>> system, often resulting in lifelong disease and disability. www.wpinstitute.

org.

>>

>> The Lerner

>> Research Institute is home to Cleveland Clinic's laboratory, translational

and

>> clinical research. Its mission: to promote human health by investigating in

the

>> laboratory and the clinic the causes of disease and discovering novel

approaches

>> to prevention and treatments; to train the next generation of biomedical

>> researchers; and to foster productive collaborations with those providing

>> clinical care. More than 1,200 people in 11 departments work in research

>> programs focusing on cardiovascular, cancer, neurologic, musculoskeletal,

>> allergic and immunologic, eye, metabolic, and infectious disease. The

Institute

>> also is an integral part of the Cleveland Clinic Lerner College of Medicine

of

>> Case Western Reserve University.

>>

>>

>> The National Cancer Institute (NCI)

>> leads the National Cancer Program and the NIH effort to dramatically reduce

the

>> burden of cancer and improve the lives of cancer patients and their families,

>> through research into prevention and cancer biology, the development of new

>> interventions, and the training and mentoring of new researchers. For more

>> information about cancer, please visit the NCI Web site at http://www.cancer.

gov or call NCI's Cancer

>> Information Service at 1-800-4-CANCER (1-800-422-6237) .

>>

>> The National

>> Institutes of Health (NIH) -- The Nation's Medical Research Agency --

includes

>> 27 Institutes and Centers and is a component of the U.S. Department of Health

>> and Human Services. It is the primary federal agency for conducting and

>> supporting basic, clinical and translational medical research, and it

>> investigates the causes, treatments, and cures for both common and rare

>> diseases. For more information about NIH and its programs, visit

<www.nih.gov>.

>> ------------ --------- --------- -

>> REFERENCE:

>> Lombardi VC, Ruscetti FW, Gupta JD, Pfost MA, Hagen KS, DL,

>> Ruscetti SK, Bagni RK, Petrow-Sadowski C, Gold B, Dean M, Silverman RH, and

>> Mikovits JA. Detection of Infectious Retrovirus, XMRV, in Blood Cells of

>> Patients with Chronic Fatigue Syndrome. Online October 8, 2009.

>> Science.

>>

>>

>> ##

>>

>> This NIH News Release is available online

>> at:

>> <http://www.nih. gov/news/ health/oct2009/ nci-08.htm>.

>>

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