Re: humm, what about estrogen effects of certain myco's ?

December 19, 2009

no thoughts on this?

FUSARIUM, ZEARALENONE MYCOTOXIN,SIMULAR TO NATURALLY OCCURING ESTROGENS.

http://zearalenone.imess.net/

>

> ENVIRONMENTAL ESTROGENS INDUCE MAST CELL DEGRANULATION AND ENHANCE IGE

MEDIATED RELEASE OF ALLERGIC MEDIATORS

> http://ehp.niehs.nih.gov/members/2006/9378/9378.html

>

December 19, 2009

fusarium exposure from indoor environments may be rare but it does happen. hard

to say, maybe other molds or chemicals that could be possably found in these

water damaged building could also cause estrogen effects. I think there might be

some answers here as to why some might show IgE mediated effects and some dont.

maybe it possable that it depends on just exactly what we were exposed to.

the mast cell effects and knowing they play in with the mucosa linings and the

damage that can happen to the mucosa linings which can be severe

and the loss of protection when the mucosa linings are damaged, I believe can

play a hudge roll here in differences relateing to exposures organ damage and

recovery. I had planed on trying to put together something on this because I

fell like I'm sometimes out in left field here, and I fell somethings are

overlooked because it's just not what most are dealing with. but I'm finding

that I cant have more than one project going at a time because it's just to

distracting for me, so I may just post the just of it and let it go from there.

> >

> > ENVIRONMENTAL ESTROGENS INDUCE MAST CELL DEGRANULATION AND ENHANCE IGE

MEDIATED RELEASE OF ALLERGIC MEDIATORS

> > http://ehp.niehs.nih.gov/members/2006/9378/9378.html

> >

>

December 19, 2009

hers some other info I had in some notes that might be of interest.

migrane, mast cells,and estrogen

http://web.mit.edu/gelliott/Public//lauren7.pdf

mast cells can secrete vascular permeability factor/vascular

endothelial cell groth factor and exhibit enhanced release after

immunoglobulin e-dependent upregulation of Fc receptor 1 expression

(cited)

http://jem.rupress.org/cgi/content/abstract/188/6/1135

ESTROGEN TREAMENT IN HLA-B27 TRANSGENIC RAT MODEL OF IMFLAMATORY BOWEL DISEASE

(CITED)

http://ajpgi.physiology.org/cgi/content/abstract/286/1/G118

environmental estrogens

http://ehp.niehs.nih.gov/members/2009/0901259/0901259.pdf

environmental estrogens affect breast development in males

http://www.environmentalhealthnews.org/ehs/newscience/environmental-estrogens-af\

fect-breast-development-in-male-rats/

mast cell degranulation breaks peripheral tolerance

http://www.medscape.com/medline/abstract/19681828

airway smooth muscle cells enhance C3a-induced mast cell degranulation following

cell-cell contact (cited)

http://www.fasebj.org/cgi/content/full/19/7/798?ck=nck

environmental estrogens

http://www.som.tulane.edu/cbr/ecme/eehome/

mastocytosis (cited)

http://jmd.amjpathol.org/cgi/content/full/8/4/412

ENHANCE IGE MEDIATED RELEASE OF ALLERGIC MEDIATORS

> > http://ehp.niehs.nih.gov/members/2006/9378/9378.html

> >

>

December 19, 2009

ok, heres another possable route of toxin poisoning to the blood stream and

straight to the brain. I can see where this could be possable with both long

term and high dose/shorter term exposure.

sorry it's not layed out, just ruff notes but I hope some well get the just of

it. haven't really heard much about this possability but we do know the

trigminal nerve and some other nerves can be affected so I dont think this

thinking would be to far out of line. I know my mucosa linings suffered some

pretty bad damage,all of it, not just my nose.

but thats what Im refering to here.

TOXINS

UP THE NOSE,TRAPPED IN MUCUS CAN GET THROUGH MUCOUS MEMBRANE INTO BLOOD

STREAM,(BLOOD POISONING)

CAUSEING INFLAMMATION OF THE MEMBRANES AROUND THE BRAIN AND SPINAL

CORD (MENINGES), INFECTION CAUSING MENINGITIS. SWELLING IN THE MENINGES

CREATES PRESSURE AROUND THE BRAIN THAT CAN CAUSE NERVE DAMAGE.

SYMPTOMS INCLUDING SEVERE HEADACHE, SENSITIVITY TO LIGHTS, STIFF NECK,

CONFUSION. DAMAGED BLOOD VESSELS,VASCULITIS.

THE NOSE IS A VERY VULNERABLE VASCULAR ORGAN. THE NOSE IS SUSCEPTABLE

TO INTERNAL IRRITATION WHICH CAN CAUSE VESSELS IN THE NOSE TO RUPTURE

CAUSEING NOSE BLEEDS. THE CAPILLARIES IN THE NOSE ARE QUITE DELICATE,

A RISE IN BLOOD PRESSURE CAN RUPTURE THE CAPILLARIES.

SOMETIMES THIS PHYSICAL BARRIER IS NOT AS FUNCTIONAL OR AS PRESENT AS

ONE WOULD HOPE

THROUGH THE NOSE BEFORE THEY PASS THROUGH THE PHARYNX,LARYNX AND

TRACHEA INTO THE BRONCHI AND THE LUNGS.

UNDER THE MUCOUS MEMBRANE IS ERECTILE TISSUE THAT IS SENSITIVE TO

TEMPERATURE AND CAUSES TISSUES OF THE AREA TO SWELL WITH THE INFLUX OF

BLOOD WHEN THERE IS AN ABUNDANCE OF COLD, DRY, OR CONTAMINATED AIR.

THIS NARROWS THE PASSAGES AND THUS SLOWS THE INCOMING AIR.

MUCUS PRODUCTION AND CLEARANCE IS REGULATED BY A COMPLEX INTERACTION OF

NERVES,BLOOD VESSELS, GLANDS,MUSCLES,HORMONES,AND CILIA.

BIOLOGICAL WARFARE,MYCOTOXIN EXPOSURE,NASAL SYMPTOMS,

BLOODY NOSE +

ACUTE BIOLOGICAL TOXINS/UNIVERSITY OF FL.

http://www.ehs.ufl.edu/Bio/toxin.htm

SINUSES,HISTAMINE,BLOOD VESSELLS

anaphalaxis-systemic reaction that accurs when a allergen is introduced

directly into the circulation, such as occurs with injection or insect

stings. a massive early phase reaction occurs throughout the body.

inner lining of the nose-mucosa,contains serous,mucus glands and a

large number of mast cells. mucosa extends to the openings leading to

the sinuses and eustachian tube where it is continuous with the mucosa

of the sinuses and middle ear,respectively, the release of

histamine,heparin and neuropeptides provokes vasodilation, swelling of

mucosa and stimulatory effects on mucus secreting glands.

swelling of mucosa can form polups blocking sinus airways.

mucosa linings-nasal,oral,respirtory,digestive.

drug delivery,nasal mucosa lining,side effects, irritation and possably

irreversible damage to the ciliary action of the nasal cavity from

chronic application, long term use not recommended.

chronic sinusitis-change in secretory function, decrease in ciliary

beating. damaged cilia stop functioning.

nasal spray may treat alzheimers/drugs targeted at nerve endings in the upper

portion of the nose can rush to the brain and bypass the protective

BBB.<<<<<<<<<<<<<<<<<<<<<<<<<

http://www.redorbit.com/news/health/1240544/nasal_spray_may_treat_alzheimers/ind\

ex.html?source=r_health

mast cells can mediate vascular permeability through regulation of the

P13-HIF-1-VEGF Axis

http://ajrccm.atsjournals.org/cgi/content/abstract/178/8/787

the cranial nerves

http://www.becomehealthynow.com/ebookprint.php?id=812

vasculitis

http://vasculitis.med.jhu.edu/whatis/symptoms.html#sinuses

----------------

December 19, 2009

We had several toxic molds in our house including Fusarium. Some of the experts

told us that Fusarium is worse than Stachybotrys.

________________________________

From: osisposis <jeaninem660@...>

Sent: Sat, December 19, 2009 9:23:23 AM

Subject: [] Re: humm, what about estrogen effects of certain

myco's ?