Guest guest Posted November 4, 2009 Report Share Posted November 4, 2009 Hi Larry, With all due respect to you and much appreciation for your wonderful sense of humor, I think we are likely talking about the same thing…with a slight discrepancy in the labeling of ‘the parts’. By definition, the central nervous system (CNS) refers to the brain and spinal cord only. http://faculty.washington.edu/chudler/nsdivide.html  The cranial nerves and spinal nerves branch out from the central nervous system at nerve roots and then extend into the rest of the body. These cranial and spinal nerves are our peripheral nervous system, which connect our body with our central nervous system (brain/spinal cord).  CRANIAL NERVES  The cranial nerves extend out from the brainstem (or nose/eyes) to the head/neck region.  According to research biologist, Schutzer: -         -    There are 12 pairs of cranial nerves, which are part of the peripheral nervous system. -         -    Ten pairs of the cranial nerves arise from the brain stem, while the other two pairs (I and II) arise from the nose and eyes. -         -    Nerves I and II are sensory only while III - XII are mixed (sensory and motor).  http://fido.pcc.edu/reserves.archived/Schutzer,/Fall02/BI232/U03-Brain & Cr\ ainalNerve.pdf   SPINAL NERVES  The spinal nerves extend out from the spinal cord to the rest of the body. In other words, that nerve in your toe is a “spinal nerveâ€.  For an excellent explanation of how the spinal nerves connect to the spinal cord and branch out to the rest of the body, see…  http://www.apparelyzed.com/spinalcord.html  CMT affects the peripheral nervous system, i.e. the spinal and cranial nerves. It used to be believed that the cranial nerves were spared, but researchers discovered that this isn’t true. https://www.researchgate.net/publication/11641231_Vocal_fold_paresis_of_Charcot-\ Marie-Tooth_disease  Not everyone is symptomatic, of course, and different types of CMT are more likely to produce symptoms, but it is definitely possible for cranial nerves to be impacted.  The fact that hearing may be affected by CMT is well-documented: http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=118300 http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601097  I‘m not a doctor and I certainly do not intend any disrespect to anyone's knowledge. Just want to clarify what we are talking about. If I’ve misrepresented anything here, please post the references, so I can get clarification myself.  Quote Link to comment Share on other sites More sharing options...
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