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Felicia -

I was doing a search on Flagyl (metronidazole) to get info to present to my

dr about my concerns. One of the serious cautions is : <can cause a

peripheral neuropathy with sensory disturbances e.g. at the hands and feet.

Neuropathy is often only slowly reversible or not reversible at all >

Someone at a MGH website wrote in: <<one possible side effect to be

concerned about is the potential for exaserbation of underlying peripheral

neuropathy in patients that may have any form of neuropathy or may have risk

factors for neuropathy such as family history of carpel tunnel or high

arches in the feet.

In the case of underlying neuopathy Flagyl (a Known neuro-toxin)can cause

the exaserbation and progression of underlying neuropathy even after the

cesation of administering of the drug. in general the affected areas are the

peripheral nerves (feet and hands). this is punctuated by increasing

numbness and marked pain sensitivity.Personally i have been off Flagyl for

over one year and the progression of the neuropathy is continuing and is

quite painfull. >>

Then I came across a website that gave the dif names it's prescribed under.

Dear Lord, Metrogel is one of them.

I am the kind of person that saves WAY too much stuff. I have all these

tubes of things I was prescribed, but never got around to throw away. One is

Metrogel. If my foggy memory serves me right, this was given to me in 1997

(maybe this is one time being a clutterbug is good). Either right before or

right after my hysterectomy.... and that's when my symptoms started (the RA,

or FMS, or whatever I have).

Now I'm REALLY upset, wondering if this drug is the cause of my problems.

Do you (or anyone else) know how I can research this, or if you know of

anyone who has long term damage due to this drug?

Lyn (trying to stay unflustered)

_________________________________________________________________

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Re: rheumatic Flagyl

>

>

> > Felicia -

> >

> > I was doing a search on Flagyl (metronidazole) to get info to present to

> my

> > dr about my concerns. One of the serious cautions is : <can cause a

> > peripheral neuropathy with sensory disturbances e.g. at the hands and

> feet.

> > Neuropathy is often only slowly reversible or not reversible at all >

> >

> > Someone at a MGH website wrote in: <<one possible side effect to be

> > concerned about is the potential for exaserbation of underlying

peripheral

> > neuropathy in patients that may have any form of neuropathy or may have

> risk

> > factors for neuropathy such as family history of carpel tunnel or high

> > arches in the feet.

> > In the case of underlying neuopathy Flagyl (a Known neuro-toxin)can

cause

> > the exaserbation and progression of underlying neuropathy even after the

> > cesation of administering of the drug. in general the affected areas are

> the

> > peripheral nerves (feet and hands). this is punctuated by increasing

> > numbness and marked pain sensitivity.Personally i have been off Flagyl

for

> > over one year and the progression of the neuropathy is continuing and is

> > quite painfull. >>

> >

> > Then I came across a website that gave the dif names it's prescribed

> under.

> > Dear Lord, Metrogel is one of them.

> >

> > I am the kind of person that saves WAY too much stuff. I have all these

> > tubes of things I was prescribed, but never got around to throw away.

One

> is

> > Metrogel. If my foggy memory serves me right, this was given to me in

1997

> > (maybe this is one time being a clutterbug is good). Either right before

> or

> > right after my hysterectomy.... and that's when my symptoms started (the

> RA,

> > or FMS, or whatever I have).

> >

> > Now I'm REALLY upset, wondering if this drug is the cause of my

problems.

> >

> > Do you (or anyone else) know how I can research this, or if you know of

> > anyone who has long term damage due to this drug?

> >

> > Lyn (trying to stay unflustered)

> > _________________________________________________________________

> > Get your FREE download of MSN Explorer at http://explorer.msn.com

> >

> >

> >

> > To unsubscribe, email: rheumatic-unsubscribeegroups

> >

> >

> >

>

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  • 1 month later...
Guest guest

Yes, Jan, you're right. My dr had prescribed Flagyl, and I was told on this

list that it is very toxic. I went to the website of the manufacturer to

read the 'handout' (forget the name of the manufacturer, but a search should

locate it), and I found out it should not be given to anyone with neuropathy

& can cause permanent damage. Since I have not had any decent med care, and

since I have needles and pins pain, I didn't want to chance permanent

damage. There is a very clear warning in the beginning of the pkg insert,

but I cannot remember what it was! Here is something that I saved on Flagyl:

http://www.infomed.ch/100drugs/menzadre.html

Metronidazole: Adverse Reactions

High doses or long-term administration of metronidazole can cause a

peripheral neuropathy with sensory disturbances e.g. at the hands and feet.

Neuropathy is often only slowly reversible or not reversible at all.

Neutropenia can also develop. Metallic taste in the mouth, nausea, upper

abdominal pain, or headaches sometimes occur following usual therapeutic

doses. Convulsions, ataxia, skin problems (skin rashes, urticaria), and

vaginal candidiasis are not as common. Isolated cases of pancreatitis,

cystitis, mucous colitis, and hemolysis have been observed. Mutagenic

effects have been observed in animal experiments; no carcinogenic effect has

yet been demonstrated in man.

and:

one possible side effect to be concerned about is the potential for

exaserbation of underlying peripheral neuropathy in patients that may have

any form of neuropathy or may have risk factors for neuropathy such as

family history of carpel tunnel or high arches in the feet.

In the case of underlying neuopathy Flagyl (a Known neuro-toxin)can cause

the exaserbation and progression of underlying neuropathy even after the

cesation of administering of the drug. in general the affected areas are the

peripheral nerves (feet and hands). this is punctuated by increasing

numbness and marked pain sensitivity.

>From: Jan Gunter <janwg@...>

>rheumatic

>Subject: rheumatic Flagyl

>Date: Fri, 23 Mar 2001 05:26:34 -0600

>

>It seems like I recall that there was quite a discussion about Flagyl a

>while back. Can anyone enlighten me? Dr. DeWet has prescribed Flagyl for

>Austin along with all the other stuff he's doing. He said one study showed

>that 50% of RA patients recovered with flagyl. Suddenly last night it

>seemed like I'd heard bad things about it from this group.

>

>Jan

>

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  • 1 year later...

Sorry I just realised Flagyl is an anti bacterial, I thought it was

an anti fungal. I just read it can actually make yeast problems

worse.

Lindy

> Reading the archive posts I notice that some people are being

> treated with Flagyl as well as Minocin. Would you recommend asking

> for this from my doctor, or is it only advised when there are

active

> symptoms of systemic fungal infection? Is it mainly taken for its

> anti fungal properties, because I've read that it also has

> antibiotic properties? Also, is it taken indefinitely or for a

> limited course? My doctor is anti AP and very conservative in his

> ideas. I would need to put a convincing case for the use of

> Flagyl.

>

> Thanks

>

> Lindy

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Dear Lindy,

You said, " Sorry I just realised Flagyl is an anti bacterial, I thought it was

an anti fungal. I just read it can actually make yeast problems

worse. "

That's interesting, because I was almost sure my daughter's

doctor has her on it as an anti-fungal.

Ellen McCool

rheumatic Re: Flagyl

Sorry I just realised Flagyl is an anti bacterial, I thought it was

an anti fungal. I just read it can actually make yeast problems

worse.

Lindy

> Reading the archive posts I notice that some people are being

> treated with Flagyl as well as Minocin. Would you recommend asking

> for this from my doctor, or is it only advised when there are

active

> symptoms of systemic fungal infection? Is it mainly taken for its

> anti fungal properties, because I've read that it also has

> antibiotic properties? Also, is it taken indefinitely or for a

> limited course? My doctor is anti AP and very conservative in his

> ideas. I would need to put a convincing case for the use of

> Flagyl.

>

> Thanks

>

> Lindy

To unsubscribe, email: rheumatic-unsubscribeegroups

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  • 4 months later...
Guest guest

rheumatic Re: flagyl

> My doctor also put me on liver support as Flagyl can be hard on your

> liver. (Milk thistle, alpha lipoic acid, N acetyl cysteine, zinc

> citrate, d-glucarate, MSM) It's supposed to help dampen down the

> side effects too.

Smart doctor! These are excellent supplements for anyone on the AP.

Ethel

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Guest guest

Hi ,

I started Flagyl almost 3 weeks ago. My doctor wanted me to take

1500 mg per day for 10 days! I had so many side effects from it

(metallic taste, sick to my stomach, loss of appetite, extreme

nausea, dizziness & light-headed) that I could only take 750 mg per

day at the absolute max! Even at that, I barely got through the 10

days. However, my joint pain reduced even further (I am taking

Minocin 200 mg/day & Nystatin powder tid... I took Diflucan for 21

days earlier). He felt that since it was having a positive effect,

could I stand taking 500 mg per day for about another month. It

turns out that if I take the 500 mg at once just before I go to bed,

I have the side effects while I sleep and hardly notice them. (Other

than it makes me sleep like a log!)I was either herxing at first or

my body has finally adjusted to the drug, because I can tolerate

that dose quite easily now. (after 2 weeks of hell!)

So, maybe you need to take your dosage more slowly and build up

gradually, letting your body tolerate the medication.

My doctor also put me on liver support as Flagyl can be hard on your

liver. (Milk thistle, alpha lipoic acid, N acetyl cysteine, zinc

citrate, d-glucarate, MSM) It's supposed to help dampen down the

side effects too.

My joint symptoms are pretty minimal now... I only need to take one

Vioxx every 4 days, just to keep the inflammation down to a

low 'roar'.

Good luck!

Toby

> hi everyone...my AP doc just added flagyl to minocycline and

clindy

> IV's. i took my first dose last night and had awful stomach pain

> this morning and feel achey. but i am not sure it was that. can

> never be sure. just wondering others experience with flagyl.

maybe

> its die off/herx. if anyone is taking flagyl and has anything to

> share (hopefully good) then please share with me. it was my idea

> to start it cuz a lot of my symptoms started in the gut when i

first

> got sick. thank you!

>

> rachael

> dermatomyositis

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  • 3 weeks later...
Guest guest

I took the Minocin/Nizoral combo until the last month when Sentef decided

to put a few patients for the first time on the Flagyl and I went on it for 30

days. . In all honesty, I think I would have done well without the Flagyl and

still gone into remission. If you have concerns about the flagyl, I would

certainly give just the Minocin/Nizoral combo a try and see if you get into

remission on it. I feel certain that I would have still reached remission

....maybe it might have taken a bit longer...but remission just the same without

the

flagyl. Again we are all different Go with your gut feelings. You can always

add the flagyl later if the two dont seem to work. Just my 2 cents. Martha

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  • 5 months later...

Hi Diane,

I started it 500 mg mwf and then was able to go up from there. Yes it

was a herxbut I just endured it as it was not disabling. I was

already on minocin 7 yrs. He prescrin\beds usually 500 a day every

day for his protocol and some take 100 a day as he did( dr Sentef)

Love

Marge

> From what I understand the flagyl has to be started VERY slowly and

you have to work up to 250 mg. It is similar to the other

antibiotics, and you will herx if started at too high a dosage. A

well known lyme doc says some can only start out w/ a sliver of a tab

and then work up. Hope that helps.

> Diane

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  • 5 months later...
Guest guest

In a message dated 6/24/2004 3:06:38 PM Eastern Standard Time,

mailbin@... writes:

Has anyone had oral thrush and if so what are the symptoms

Oh yes. Look at your tongue, it's probably white. I had prescription drugs

for it, but it still didn't get rid of it. I now take acidophilus before

every meal and am also taking Candida Clear (contains Pau D'Arco, oregano oil,

Black Walnut and Caprylic Acid) My doctor recommended these things, so I'm

giving it a try. Just started on it, so don't know yet how well it works.

The Probiotics definitely help and need to be taken while on Antibiotics

because long term antibiotic use will cause yeast problems. Mine got really bad

when I was on daily antibiotics, but cutting back to MWF and taking the

acidophilus have improved things quite a bit. Not completely though so I'm

trying

the additional things.

Jill

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Guest guest

You might want to include " Para-Cleanse " (Nature's Sunshine) as it has everything

you mention, and then some . I use it every other month for 10 days, and have

seen wonderful results. Not 100% yet, but have seen an improvement.

I also decided to try Flagy (200mg) twice a day, and have see an improvement.

No more monthly IV's, or any other drugs.

Jknitl@... wrote:

In a message dated 6/24/2004 3:06:38 PM Eastern Standard Time,

mailbin@... writes:

Has anyone had oral thrush and if so what are the symptoms

Oh yes. Look at your tongue, it's probably white. I had prescription drugs

for it, but it still didn't get rid of it. I now take acidophilus before

every meal and am also taking Candida Clear (contains Pau D'Arco, oregano oil,

Black Walnut and Caprylic Acid) My doctor recommended these things, so I'm

giving it a try. Just started on it, so don't know yet how well it works.

The Probiotics definitely help and need to be taken while on Antibiotics

because long term antibiotic use will cause yeast problems. Mine got really bad

when I was on daily antibiotics, but cutting back to MWF and taking the

acidophilus have improved things quite a bit. Not completely though so I'm

trying

the additional things.

Jill

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  • 1 month later...
Guest guest

Although it wasn't with Flagyl, my son had this when we would start

something that helped with constipation a little too well. It seemed

much worse before the encopresis remedy because the colon was too

stretched and he didn't have good feeling or muscle control in that

area.

After the treatment when the muscles/nerves had returned to a where

they should have been, this didn't happen any more.

.

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Guest guest

Thank You, if the effect is temporary, limited to the treatment

medication), then we can handle it. I'm so hopeful and nervous. My son

won't shut up. Not stimming, not echolalia, but so imaginative and so

communicative, so interactive with his environment. (almost but not quite

like that breakthrough we had last year while on the augmenten, although

that was very dramatic it lasted only a couple of days, and then he

regressed). While the pronunciation needs some work, he is much more readily

understood nowadays. I've gotten in the habit, if he has repeated himself to

someone several times, of echoing what he said, and more often than not

lately people will say to me, " oh, I heard him " . The defiance, the lying,

the manipulation, the comprehension, it's amazing. Of course getting him to

stay focused on task, like cleaning things up, etc. is a nightmare. Even

when it comes to activities he enjoys like arts and crafts time, it's a

struggle to complete anything. Plus he is becoming more meticulous with his

paper work, and he can see somewhat now of black and white. We have a

computer game, and it allows you to print the screen, so ph was playing

a letters game, the letters are hidden in the picture and you have to find

them, well ph printed it out in black and white and came to me, pointed

out an N, K, O and one other letter I can't recall. I was stunned. My

husband pointed out that on the computer it's all in color so of course he

can see it, and probably memorized where things were, but still, it took

some ability to find it on the black and white page. It's like me, I can

never figure out what those fuzzy pictures in the mall are, until someone

tells me, and then I can " see " the picture hidden within. Lots of prayers,

but I'm hopeful.

Re: Flagyl

> Although it wasn't with Flagyl, my son had this when we would start

> something that helped with constipation a little too well. It seemed

> much worse before the encopresis remedy because the colon was too

> stretched and he didn't have good feeling or muscle control in that

> area.

>

> After the treatment when the muscles/nerves had returned to a where

> they should have been, this didn't happen any more.

>

> .

>

>

>

>

>

>

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  • 1 year later...

In a message dated 24/02/2006 07:10:45 GMT Standard Time, AndyCutler@...

writes:

Flagyl is a horrendous drug in terms of toxicity and side effects.

>>>Thats why I prefer 3 days of 10ppm Collodial Silver to 10 days of Flagyl

Mandi in UK

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>

> Does flagyl need to be taken with food? The pharmacist told me it

does, but

> I'm going to have a hard time getting my son to eat when I wake him

early in

> the morning to take it. Just wondering what other people have

done. Thanks.

>

>

Flagyl is a horrendous drug in terms of toxicity and side effects.

What is this for?

Andy

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> My son appears to have a significant gut yeast and bacteria issue. Flagyl

> will be used very short term for the bacteria

If you can, please avoid this. It is a drug with very bad side effects. It was

prescribed to my son many years ago for parasites (apparently this stuff is so

chemical, it kills everything) and poor kid felt so bad... I couldn't give more

than two doses.

Also, I read about some studies where Flagyl caused cancer in animals.

Valentina

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  • 2 years later...

Oh jeepers...don't tell Andy that, you'll open another can of worms

there. With regards to silver being toxic.

>

>

> In a message dated 24/02/2006 07:10:45 GMT Standard Time,

AndyCutler@...

> writes:

>

> Flagyl is a horrendous drug in terms of toxicity and side effects.

>

>

>

> >>>Thats why I prefer 3 days of 10ppm Collodial Silver to 10 days

of Flagyl

>

> Mandi in UK

>

>

>

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My son was on Vancomyacyn and had the head vibration. Then they put

him on Flagyl with no head vibration. You might try a switch to Vanco.

>

> my dd is getting a vibrating sensation in her head, since starting the

> Flagyl. Could this be die-off? She said she keeps getting firing

> thoughts too. Any suggestions?

>

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She was on it once before and I didn't see this reaction. I will see

how it goes tomorrow. Thanks!

On Oct 16, 2008, at 8:42 PM, panderson14me wrote:

> My son was on Vancomyacyn and had the head vibration. Then they put

> him on Flagyl with no head vibration. You might try a switch to Vanco.

>

>

> >

> > my dd is getting a vibrating sensation in her head, since

> starting the

> > Flagyl. Could this be die-off? She said she keeps getting firing

> > thoughts too. Any suggestions?

> >

>

>

>

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  • 8 months later...
Guest guest

My husband has a recurring C-Diff infection. The doctor wants too treat it with

Flagyl this time. It's on the CMT no no list. The doctor says his nerves are

already gone so why not? It certainly would be easier than Vancomycin which

Medco won't pay for as an out patient. Is the list absolute? What are the risks

and percentages?

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  • 8 months later...
Guest guest

Hi Judy,

I personally do not but know of others who have taken it. If I remember

correctly, one person I know feels like it really does something because she

herxes.

Good luck

Elaine

________________________________

From: jchabot <jchabot@...>

Sent: Wed, March 17, 2010 11:24:27 AM

Subject: [ ] Flagyl

Hi all,

My son is on Zith and Rifampin. The doc was going to add Tindamax, but my

insurance wouldn't cover it, so he is adding Flagyl instead. Does anyone have

any experience with this med?

thanks

Judy

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Guest guest

Thanks Elaine,

Dr.J did tell me to stop the med if he has a real bad herx, so I'm guessing

that is the case with this med.

Judy

________________________________

From: <ecckwalk@...>

Sent: Wed, March 17, 2010 3:43:23 PM

Subject: Re: [ ] Flagyl

 

Hi Judy,

I personally do not but know of others who have taken it. If I remember

correctly, one person I know feels like it really does something because she

herxes.

Good luck

Elaine

____________ _________ _________ __

From: jchabot <jchabotsnet (DOT) net>

Sent: Wed, March 17, 2010 11:24:27 AM

Subject: [ ] Flagyl

Hi all,

My son is on Zith and Rifampin. The doc was going to add Tindamax, but my

insurance wouldn't cover it, so he is adding Flagyl instead. Does anyone have

any experience with this med?

thanks

Judy

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