Re: What is GP6[Gucose 6 phosphate deficiency]

[Guest guest]

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Gucose 6 phosphate deficiency. It generates nicotonamide adinine

dinucleotide[nadph] by catalizing the conversion of glucose 6

phosphate into6 phosphogluconate. The nadph is used by the red blood

cells to reduce potential toxic oxidizing agents that accumulate

with exposure to drugs/toxins chemicals and infections. Emlar cream

whish is lidocane is often used as a numbing cream before a shot or

blood draw is contraindicated for folks with GP6 In

EOHarm , " J lessard " wrote:

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> Vit.c Contraindications, Carcinogenicity & Mutagenicity

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> Vit.c Contraindications, Carcinogenicity & Mutagenicity

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> 4.3 Contraindications

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> Ascorbic acid is contraindicated in patients with

> hyperoxaluria (Dollery, 1991) and G-6-PD deficiency

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> Does anyone know what G-6-PD deficiency is? Is it a liver enzyme?

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> Does it have anything to do with not tolerating Sulfa drugs and/or

Vit.C?

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> 7.3 Carcinogenicity

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> It has been reported that there is no evidence of

> carcinogenicity (Dollery, 1991). However, some studies

> suggest that vitamin C may amplify the carcinogenic effect of

> other agents. Scwartz et al. (1993) report that L-ascorbic

> acid increases the oral carcinoma size induced by

> dimethylbenz(a)anthracene. Also, butylated hydroxyanisole

> induced forestomach carcinogenesis in rats (Shibata et al.,

> 1993) and the K2CO3 induced promotion of bladder

> carcinogenesis in rats (Fukushima et al., 1991) were both

> amplified by the administration of ascorbic acid.

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> Vit. C may amplify carcinogenesis.

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> .5 Mutagenicity

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> Ascorbic acid is reported to increase the rate of

> mutagenesis in cultured cells but this only occurs in

> cultures with elevated levels of Cu2+ or Fe2+ . This

> effect may be due to the ascorbate induced generation of

> oxygen-derived free radicals. However, there is no evidence

> of ascorbate induced mutagenesis in vivo (Diplock,

> 1995).

> Here it says that Vit. C can increase mutagenesis in those with

elevated levels of copper or iron. Don't most autistics have copper

overload?

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> http://www.inchem.org/documents/pims/pharm/ascorbic.htm

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