Re: Autism, Other Disorders Linked To Post-Natal Factors:

[Guest guest]

This is an issue on which parents really end up having to fend for

themselves and get " google degrees " because there's so few honest

resources out there. DAN docs don't tend to be neurologists and, as

you've probably figured out, neurologists tend to be the worst

motherf***ers regarding denial of drug side effects. Pardon my French

but it's a revolting situation. They're the field which TRULY has

patients over a barrel because patients often suffer from seizures

and have few other options than to control with meds.

I've heard very, very few positive referrals for neurologists, except

I'd been told about a Dr. in Houston who's referred by some

DANs and a Dr. Perlmutter in FL who apparently doesn't love the

drugs. Only a doctor who has reservations about these meds would even

begin to know what to do to treat drug side effects.

One hint I got from a retired neuro was that all psychotropes,

including anti-seizure drugs, have the potential to induce

mitochondrial dysfunction. Maybe you can get mito function tested and

use that approach of treatment to start with if you aren't already.

Calming brain inflammation is probably key.

> > > >

> > > > Autism, Other Disorders Linked To Post-Natal Factors: Study

> > > >

> > > > http://is.gd/bgg1

> > > >

> > > > Washington (AFP) — Autism and obsessive-compulsive

> > disorders

> > > may

> > > > be linked to factors other than genetics, despite widely held

> > > beliefs

> > > > otherwise, according to a study published Wednesday in the

> > American

> > > > journal Neuron.

> > > > When researchers removed the protein FKBP12, found in

both

> > > > humans and mice, from studied mice, the animals demonstrated

> major

> > > > neurological and behavioral changes.

> > > > FKBP12 is known to regulate the activity of mTOR, an

> enzyme

> > > that

> > > > affects the ability to change behavior and regulates

connections

> > > > between neurons, thus playing a key role in learning and

> > > memorization.

> > > > The findings of the study, led by researchers at New

York

> > > > University's Center for Neural Science and the Baylor College

of

> > > > Medicine, may enhance scientific and medical understanding of

> > > > disorders such as autism, which affects about one in 150

> children

> > in

> > > > the United States, according to the US Centers for Disease

> > Control

> > > and

> > > > Prevention.

> > > > Results showed an increase of mTOR signaling after

> removing

> > > the

> > > > protein from the brains of mice late in development. The mice

> also

> > > > demonstrated an enhanced ability to change connections between

> > > > neurons, especially in those parts of the brain used for

memory.

> > > > Removing FKBP12 reduced the mice's capacity to analyze,

> > > respond

> > > > and adapt to new situations, according to the study.

> > > > Once the mice learned a task, such as navigating a

maze,

> > they

> > > > had difficulty learning how to travel through a different

> version

> > of

> > > > the maze. This type of enhanced perseveration, or pathological

> > > > repetition, is often observed in individuals suffering from

> > autism

> > > or

> > > > other neurological disorders.

> > > > " Our results suggest that FKPB12 regulates neuron

> signaling

> > > that

> > > > curbs the manifestation of traits observed in several

> neurological

> > > > disorders including autism, obsessive-compulsive disorder and

> > > > schizophrenia, " said NYU neuroscientist Klann, the

study's

> > lead

> > > > researcher.

> > > > These disorders are widely believed to be " determined

in

> > utero

> > > > by genetic hormonal and environmental factors, " he adds.

> > > > But " because our study indicates that postnatal release

> of

> > > mTOR

> > > > activity can result in certain perseverative behaviors, it

> > > challenges

> > > > the idea that some aspects of these conditions are

> developmentally

> > > > predetermined. "

> > > >

> > >

> >

>