Re: How do you classify CMT 1A and Ascorbic Acid?

[Guest guest]

How do you classify cmt1A? does this mean we only have to take the ascorbic acid

for 12 months? after 12 months what's next? thank you...

Ascorbic Acid Well-Tolerated in Adults with CMT1A

http://english. farsnews. net/newstext. php?nn=880820106 7

[Guest guest]

Frederick,

CMT 1A is one of the many genetic (DNA) classifications of CMT, and is the most

common form, affecting 70-75% of all people with CMT. Ascorbic Acid for 1A is

still in clinical trials - all over the world. The trials originated from the

mouse study in 2004 which is in our Files section along with all the other trial

studies thus far. Most studies up until now have concluded Ascorbic Acid doesn't

change the phenotype of CMT 1A, however the trials have been short (12 months).

The current USA trials are for 3 years, they began in 2007 (I think) so we'll

have to wait for those. They are being conducted at three centers in the Eastern

US.

If CMT 1A is proved to be helped with Ascorbic Acid, researchers will have to

work out recommended doses. Just another part of the process until we get theh

full picture.

If you search through our Archives from April 2004 onward, you'll find hundreds

of posts from people who have self-experimented with different doses of Vitamin

C (Ascorbic Acid), the amounts and the effects.

CMT 1A is dominantly inherited and characterized by demylenation. More at

http://neuromuscular.wustl.edu/time/hmsn.html#IA

Gretchen