TRIGEMINAL DAMAGE/PAIN, IMPARED NOCICEPTIVE PROCESSING

[Guest guest]

I have been told I have this. I was exposed to 9 kind of mold for years,

including aspergillus Where is more information about this connection...I

was told it was all in my head... " .I DO BELIEVE THAT BREATHING TOXINS CAN ALSO

CAUSE TRIGEMINAL NEURALGIA

"

In a message dated 1/31/2010 6:19:57 P.M. Central Standard Time,

jeaninem660@... writes:

I DO BELIEVE THAT BREATHING TOXINS CAN ALSO CAUSE TRIGEMINAL NEURALGIA

[Guest guest]

Impaired trigeminal nociceptive processing in patients

with episodic and chronic trigeminal neuralgia

http://www.walter-graphtek.com/images/dgn2007.pdf

NEUROBIOLOGY OF PERSISTENT PAIN MEDIATED BY THE TRIGEMINAL NERVE

http://grants1.nih.gov/grants/guide/pa-files/PAS-03-173.html

Partial Infraorbital Nerve Ligation as a Model of Trigeminal Nerve Injury in the

Mouse: Behavioral, Neural, and Glial Reactions.

Xu M, Aita M, Chavkin C.

Cod Referencia : J Pain. 2008 Aug 15. [Epub ahead of print]

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Department of Pharmacology, University of Washington, Seattle.

Trigeminal nerve damage often leads to chronic pain syndromes including

trigeminal neuralgia, a severely debilitating chronic orofacial pain syndrome.

Options for treatment of neuropathic pain are limited in effectiveness and new

approaches based on a better understanding of the underlying pathologies are

required. Partial ligation has been shown to effectively mimic many of the

qualities of human neuropathic pain syndromes. We have devised a mouse model of

trigeminal neuralgia using a partial infraorbital nerve ligation (pIONL) that

induces persistent pain behaviors and morphological changes in the brainstem. We

found that the pIONL effectively induced mechanical allodynia lasting for more

than 3 weeks. Cell proliferation (bromodeoxyuridine), activation of astrocytes

and microglia in the ipsilateral caudal medulla, and persistent satellite cell

reaction in the ipsilateral ganglion were observed. Neurochemical markers

calcitonin gene-related peptide, substance P were decreased in medullary dorsal

horn ipsilateral to the injury side, whereas substance P receptor NK1 expression

was increased after 8 days. Nerve injury marker ATF3 was markedly increased in

ipsilateral trigeminal ganglion neurons at 8 days after pIONL. The data indicate

that partial trigeminal injury in mice produces many persistent anatomical

changes in neuropathic pain, as well as mechanical allodynia. PERSPECTIVE: This

study describes the development of a new mouse model of trigeminal neuropathic

pain. Our goal is to devise better treatments of trigeminal pain, and this will

be facilitated by characterization of the underlying cellular and molecular

neuropathological mechanisms in genetically designed mice.

PMID: 18708302 [PubMed - as supplied by publisher]

http://dn.areastematicas.com/articulooriginal.php?id=542

I DO BELIEVE THAT BREATHING TOXINS CAN ALSO CAUSE TRIGEMINAL NEURALGIA

http://www.answers.com/topic/trigeminal-neuralgia

http://emedicine.medscape.com/article/248933-overview

[Guest guest]

Here's a link to another paper that discusses the effect on the trigeminal

nerve.

http://www.doh.wa.gov/ehp/oehas/mold.html

>

> I have been told I have this. I was exposed to 9 kind of mold for years,

> including aspergillus Where is more information about this connection...I

> was told it was all in my head... " .I DO BELIEVE THAT BREATHING TOXINS CAN ALSO

> CAUSE TRIGEMINAL NEURALGIA

> "

>

>

> In a message dated 1/31/2010 6:19:57 P.M. Central Standard Time,

> jeaninem660@... writes:

>

> I DO BELIEVE THAT BREATHING TOXINS CAN ALSO CAUSE TRIGEMINAL NEURALGIA

>

>

>

>

[Guest guest]

I think there is mention of trigeminal nerve damage here.

http://ehp.niehs.nih.gov/members/2006/8854/8854.pdf

Satratoxin G from the Black Mold Stachybotrys chartarum Evokes Olfactory

Sensory Neuron Loss and Inflammation in the Murine Nose and Brain

>

> I have been told I have this. I was exposed to 9 kind of mold for years,

> including aspergillus Where is more information about this connection...I

> was told it was all in my head... " .I DO BELIEVE THAT BREATHING TOXINS CAN ALSO

> CAUSE TRIGEMINAL NEURALGIA

> "

>

>

> In a message dated 1/31/2010 6:19:57 P.M. Central Standard Time,

> jeaninem660@... writes:

>

> I DO BELIEVE THAT BREATHING TOXINS CAN ALSO CAUSE TRIGEMINAL NEURALGIA

>

>

>

>

[Guest guest]

I was exsposed for years at work and i have problems with my trigenial

nerve in my face

In a message dated 1/31/2010 9:32:12 P.M. Eastern Standard Time,

wisec4812@... writes:

Here's a link to another paper that discusses the effect on the trigeminal

nerve.

_http://www.doh.http://www.http://www.http_

(http://www.doh.wa.gov/ehp/oehas/mold.html)

--- In _@ic_

(mailto: ) , kmartjoppa@., kma

>

> I have been told I have this. I was exposed to 9 kind of mold for years,

> including aspergillus Where is more information about this connection..

in

> was told it was all in my head... " .I DO BELIEVE THAT BREATHING TOXINS

CAN ALSO

> CAUSE TRIGEMINAL NEURALGIA

> "

>

>

> In a message dated 1/31/2010 6:19:57 P.M. Central Standard Time,

> jeaninem660@ jeaninem660@<W

>

> I DO BELIEVE THAT BREATHING TOXINS CAN ALSO CAUSE TRIGEMINAL NEURALGIA

>

>

>

> [Non-text portions of this message have been removed]

>

[Guest guest]

My name is Jill and I have been told I have trigeminal neuralgia. I too was

exposed to mold in my condo that the health dept. said was unfit to live in! I

have a laundry list of problems which I attribute to living in this mold, some

of which cannot be diagnosed to this day 10yrs later. I am a young woman who

feels her health has been stolen. Does anyone have problems with their eyes

hurting all the time and especially when reading or using a computer? p.s. u

mentioned about swelling of th nose and mine does especially when I use my eyes

to read!!???

On Sun Jan 31st, 2010 9:11 PM EST osisposis wrote:

>I think there is mention of trigeminal nerve damage here.

>http://ehp.niehs.nih.gov/members/2006/8854/8854.pdf

>

>Satratoxin G from the Black Mold Stachybotrys chartarum Evokes Olfactory

>Sensory Neuron Loss and Inflammation in the Murine Nose and Brain

>

>

>

[Guest guest]

yep,my eyes can get to hurting. I still have double vision with things up close

and I have to were magnifing glasses to correct it.

still have blurriness too. had cataracts removed but these problems were here

before cataracts got bad and still after removel.

I knew this would be the case, but try telling a eye doc that, or anyone esle

for that matter cause cataracts removel was supposed to slove all my eye

problems. also still have some light sensitivity going on and some vertigo

type symptoms. and ofcorse these can all get worse when I'm not felling the

greatest and or things that irritate the condition. and yes, I also get

inflamation in the sinuses off and on.

>

> >I think there is mention of trigeminal nerve damage here.

> >http://ehp.niehs.nih.gov/members/2006/8854/8854.pdf

> >

> >Satratoxin G from the Black Mold Stachybotrys chartarum Evokes Olfactory

> >Sensory Neuron Loss and Inflammation in the Murine Nose and Brain

> >

> >

> >

>

[Guest guest]

Yes, Jill i feel as though I also have some nerve damage. Diagnosed last october

with SBS and  even though I am working in another building (had to be removed

from the sick one) i still have alot of FATIGUE. My weekends are spent on the

sofa, recliner, or in bed trying to recoup from teaching 8th graders all week. I

feel as though I have no more social life.

[Guest guest]

some where theres full text,mexico article on this.

Mexico City Air Pollution Adversely Affects Olfactory Function and Intranasal

Trigeminal Sensitivity

http://chemse.oxfordjournals.org/cgi/content/abstract/34/9/819

project touch

http://hsc.unm.edu/som/projects/touch/datasets/ponstrigeminal.shtml

>

> Yes, Jill i feel as though I also have some nerve damage. Diagnosed last

october with SBS and  even though I am working in another building (had to

be removed from the sick one) i still have alot of FATIGUE. My weekends are

spent on the sofa, recliner, or in bed trying to recoup from teaching 8th

graders all week. I feel as though I have no more social life.

>

>

>

>

>

[Guest guest]

Trigeminal neuralgia is caused by inflammation. The inflammation occurs in

sinuses that impinge upon the branch of the trigeminal nerve, i.e. I, II or III.

The inflammation can be caused by bacteria, molds and/or volatile organic

chemicals. I you more information, contact me at the email address below.

There is considerable literature on trigeminal neuralgia. You can try medicine

and/or the National Library of Medicine (PubMed)

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

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