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Toxicology of mycotoxins

Book Series Experientia Supplementum

ISSN 1023-294X

Volume Volume 100

Book Molecular, Clinical and Environmental Toxicology

Publisher Birkhäuser Basel

DOI 10.1007/978-3-7643-8338-1

Copyright 2010

ISBN 978-3-7643-8337-4 (Print) 978-3-7643-8338-1 (Online)

DOI 10.1007/978-3-7643-8338-1_2

Pages 31-63

Subject Collection Biomedical and Life Sciences

SpringerLink Date Monday, March 01, 2010

http://www.springerlink.com/content/px32071j15177316/

PDF (294.5 KB)Free Preview

Experientia Supplementum

Molecular, Clinical and Environmental Toxicology

Volume 2: Clinical Toxicology

10.1007/978-3-7643-8338-1_2

s Luch

Toxicology of mycotoxins

R. M. Paterson1 and Lima1

(1) Centre of Biological Engineering, IBB-Institute for Biotechnology and

Bioengineering, Universidade do Minho, 4710-057 Braga, Portugal

Abstract

Humans are exposed to mycotoxins via ingestion, contact and inhalation. This

must have occurred throughout human history and led to severe outbreaks.

Potential diseases range from akakabio-byo to stachybotryotoxicosis and cancer.

The known molecular bases of toxicology run the gamut of 23 compounds, from

aflatoxins (AFs) to zearalenone, ochratoxin A and deoxynivalenol. Ergotism is

one of the oldest recognized mycotoxicosis, although mycotoxin science only

commenced in the 1960s with the discovery of AFs in turkey feed. AFs are

carcinogenic. Some others are suspected carcinogens. The effects of mycotoxins

are acute or chronic in nature. Mycotoxins are well known in the scientific

community, although they have a low profile in the general population. An

incongruous situation occurs in United States where mycotoxins from " moldy

homes " are considered to be a significant problem, although there is a general

debate about seriousness. This contrasts with the thousands of deaths from

mycotoxins that occur, even now, in the technologically less developed countries

(e.g., Indonesia, China, and Africa). Mycotoxins are more toxic than pesticides.

Studies are moving from whole animal work to investigating the biochemical

mechanisms in isolated cells, and the mechanisms of toxicity at the molecular

level are being elucidated. The stereochemical nature of AFs has been shown to

be important. In addition, the effect of multiple mycotoxins is being

increasingly investigated, which will more accurately represent the situation in

nature. It is anticipated that more fungal metabolites will be recognized as

dangerous toxins and permitted statutory levels will decrease in the future.

--------------------------------------------------------------------------------

R. M. Paterson

Email: russell.paterson@...

Lima

Email: micoteca@...

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Has anyone here tried detoxing so the body can better handle the toxin load

from the mycotoxins? It seems helping the liver, spleen, kidneys and skin

do their job more effectively would help reduce the reactions to these

mycotoxins.

I detox with extreme caution after experiencing several healing crisis.

Currently my healing regimen includes drinking Cats Claw tea to boost the

beneficial bacteria and immune system while targeting the bad bacteria,

viruses, etc. I make this tea by simmering dried Cats Claw " twigs " (aka

Uncaria), straining, then sipping the hot tea. The liquids can be simmered

longer to reduce then added to honey to make a cat's claw syrup.

I'm curious if anyone else has been successful using detox and/or natural

methods to deal with the toxin loads.

Jeri

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Jeri,

Does cat's claw boost beneifcial bacteria? I always thought that it was great

helping the body get rid of viruses, bacteria, spirocetes, etc. But never heard

about it being beneficial for the good critters. Does that also include Samento?

Up till now, I'd been going out of my way not to take it near any ingestion of

probiotics. Any feedback would be appreciated.

Thanks,

Sam

I detox with extreme caution after experiencing several healing crisis.

Currently my healing regimen includes drinking Cats Claw tea to boost the

beneficial bacteria and immune system while targeting the bad bacteria,

viruses, etc. I make this tea by simmering dried Cats Claw " twigs " (aka

Uncaria), straining, then sipping the hot tea. The liquids can be simmered

longer to reduce then added to honey to make a cat's claw syrup.

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Sam,

I recently did see a reference indicating Cat's Claw helps beneficial

bacteria. I'm looking for the reference now. Here are other references on

this herbal while I'm seeking the specific reference for you.

http://www.kcweb.com/herb/catsclaw.htm

http://www.rain-tree.com/catclaw.htm

http://www.herbwisdom.com/herb-cats-claw.html

http://www.canceractive.com/cancer-active-page-link.aspx?n=1928 & Title=Cats%20Cla\

w%20Uno%20de%20Gato

http://www.umm.edu/altmed/articles/cats-claw-000229.htm

Okay, HERE we go! great article, though not much on Cat's Claw / Uncaria

http://www.positivehealth.com/article-view.php?articleid=479

I'm still not finding the reference on cat's claw helping beneficial

bacteria. It's out there somewhere, I just saw it this week. When I see it

again I'll post it for you.

Jeri

On Sat, Mar 13, 2010 at 2:46 PM, Sam <yaddayadda53@...> wrote:

>

>

> Jeri,

>

> Does cat's claw boost beneifcial bacteria? I always thought that it was

> great helping the body get rid of viruses, bacteria, spirocetes, etc. But

> never heard about it being beneficial for the good critters. Does that also

> include Samento? Up till now, I'd been going out of my way not to take it

> near any ingestion of probiotics. Any feedback would be appreciated.

>

> Thanks,

> Sam

>

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Thanks very much for this info, Jeri. Look forward to the other on it's effect

on beneficial bacteria if you can find it. 

Thanks again,Sam

--- On Sat, 3/13/10, Jeri Zerr <jerizerr@...> wroteSam,

I recently did see a reference indicating Cat's Claw helps beneficial

bacteria. I'm looking for the reference now. Here are other references on

this herbal while I'm seeking the specific reference for you.

http://www.kcweb. com/herb/ catsclaw. htm

http://www.rain- tree.com/ catclaw.htm

http://www.herbwisd om.com/herb- cats-claw. html

http://www.cancerac tive.com/ cancer-active- page-link. aspx?n=1928 & Title=Cats%

20Claw%20Uno% 20de%20Gato

http://www.umm. edu/altmed/ articles/ cats-claw- 000229.htm

Okay, HERE we go! great article, though not much on Cat's Claw / Uncaria

http://www.positive health.com/ article-view. php?articleid= 479

I'm still not finding the reference on cat's claw helping beneficial

bacteria. It's out there somewhere, I just saw it this week. When I see it

again I'll post it for you.

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