Guest guest Posted November 5, 2010 Report Share Posted November 5, 2010 Joe, heres another question, are you allergic to the same molds that you also have a non-allergic reaction to? in other words, ever had both a allergic and non-allergic reaction to a mold and it's toxins at the same time? immediate reaction possabily lasting a few days plus delayed reactions starting in and lasting days to weeks,months? > > I began my first, of many allergy testings, for mold, foods, dust, and pollen in the year 1952, at the age of 9. At that time " specific IgE testing for certain molds " had not yet bee Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2010 Report Share Posted November 5, 2010 Hi Jeanine, I do not understand what you mean by " allergic sinusitiis " . Here is a link to an ENT doctor: http://www.entnet.org/HealthInformation/rhinitis.cfm Their web site discusses " allergic rhinitis " and " rhinosinusitis " . But, there is no mention of " allergic sinusitis " . Over ten years ago, research published by the Mayo Clinic confirmed that 90% of all CHRONIC sinusitis is " FUNGAL " (mold) in origin. Only ACUTE sinusitis (lasting for 2 weeks or less) is bacterial in origin. Unfortunately, the linked ENT web site, like MOST ENT's, have not gotten the word yet. If you are saying that the sinuses can have an " allergic " mold reaction, then I would have to say that my 58 years of allergic reactivity has convinced me that this is not true. I would agree with the Mayo Clinic (I'll locate and post their research, here, tomorrow), that CHRONIC [lasting more than 2 weeks] sinusitis is a toxic reaction to mold, NOT an allergic reaction to mold. It is not JUST a toxic reaction. There is an actual colony of invasive mold, growing inside the sinuses. I have had this condition, in the past. Here is a disgusting, but accurate, diagnostic procedure you can conduct on your own sinuses, to determine if you have a mold colony growing inside your sinuses. I discovered this, using my own body. Grab hold of the end of your mucus, with a tissue, at the opening of your nostril. Slowly pull the mucus out of your nose, taking care to NOT pinch off the mucus, to cause it to break. If you can get an intact continuous " thread " of mucus to extend at least 8 inches, between your nostril and your tissue, then you have diagnosed yourself as having " fungal sinusitis " . Once " self-diagnosed " you should get a prescription for an anti-fungal pill (for systemic relief) and an anti-fungal nasal spray. A nasal spray, by itself, will not do the job, as the mucus will prevent any spray from penetrating far back enough to reach the sinuses. You should also use the " NielMed " nasal irrigator [available in the 'colds' section of every chain drug store]. Make sure that you squirt the liquid into your nose, with their " squirt bottle " and not a neti pot, as a neti pot does not project enough force to get far enough back, into your sinuses. Use this while standing over a sink, as the liquid that went into your nose, will leave your body through your mouth, carrying with it all the mucus and phlegm that your sinuses are storing. Don't get frightened at the massive amount of gook that you cough out [it's actually more of a choking out process]of your sinuses, through your mouth, into the sink. A bad case of fungal sinusitis will produce more gook than it seems possible that the human body could contain. As to your question about " allergic lung disease " , the primary such disease, is asthma, which I have had, concurrent with my allergies, since the age of nine. There are other " allergic lung diseases " , but, percentage-wise, if there is something wrong with your lungs that IS NOT asthma, it is a better bet to suspect bacterial or " invasive " fungal involvement, until you take the necessary C.T. Scans to make a proper diagnosis. Once you have " fungal balls " growing inside your lungs, it is irrelevant to focus on " allergy " , because you have something far more urgent to deal with. The only times that I have been colonized with mold, have been cases of simple oral candidiasis, which was always brought on by overuse of antibiotics, or failure to thoroughly rinse my mouth and gargle, after use of oral corticosteroid inhalers, which I use for my asthma. Whether or not such occurances are more frequent during periods of systemic toxic mold exposure, is something that medical research will have to investigate. Aside from my allergies and asthma, I have been lucky enough to not experience any other autoimmune diseases.[unless you classify my toxic mold reactivity and my multiple chemical sensitivity as " autoimmune " diseases]. Joe .................................................................................\ ............... Re: Toxin Help Posted by: " osisposis " jeaninem660@... osisposis Thu Nov 4, 2010 10:09 pm (PDT) a few more questions?, do you have allergic sinusesitis, or allergic lung disease, are you colonized with mold? do you have autoimmune disorders, just wondering. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2010 Report Share Posted November 5, 2010 listspub, no I dont have the dreaded, I have the SBS 17-2-52A, > > Jeanne.. I am really curious about this because I have one of Shoe's " dreaded genes " that he repeats does not get better most of the time.. and you know he repeats that csm is the best answer for those that it can help and implies that those that it cant help are basically lost causes.. > > as much as I appreciate him... this part had really effected me badly in a psychological way and i resent him for these statement. > > so Im wondering.. do you have one of his " dreaded genes " and still improved without the csm? > > My daughter also has a " dreaded " and we jsut had a rough night.. to say Im worried for her is an understatement and I would have to be desparate to give this to her.. > > and though I hope to complete a month and see how it goes, I dont want to stay on it/ > > Thanks.. > > Robin Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2010 Report Share Posted November 5, 2010 SORRY jOE,Rs, woops capps, have you ever had tottal IgE tested? do you have a average or certain range? number? > > Hi Jeanine, > > I do not understand what you mean by " allergic sinusitiis " . Here is a link to an ENT doctor: > http://www.entnet.org/HealthInformation/rhinitis.cfm > > Their web site discusses " allergic rhinitis " and " rhinosinusitis " . But, there is no mention of " allergic sinusitis " . Over ten years ago, research published by the Mayo Clinic confirmed that 90% of all CHRONIC sinusitis is " FUNGAL " (mold) in origin. Only ACUTE sinusitis (lasting for 2 weeks or less) is bacterial in origin. Unfortunately, the linked ENT web site, like MOST ENT's, have not gotten the word yet. If you are saying that the sinuses can have an " allergic " mold reaction, then I would have to say that my 58 years of allergic reactivity has convinced me that this is not true. I would agree with the Mayo Clinic (I'll locate and post their research, here, tomorrow), that CHRONIC [lasting more than 2 weeks] sinusitis is a toxic reaction to mold, NOT an allergic reaction to mold. It is not JUST a toxic reaction. There is an actual colony of invasive mold, growing inside the sinuses. I have had this condition, in the past. > > Here is a disgusting, but accurate, diagnostic procedure you can conduct on your own sinuses, to determine if you have a mold colony growing inside your sinuses. I discovered this, using my own body. Grab hold of the end of your mucus, with a tissue, at the opening of your nostril. Slowly pull the mucus out of your nose, taking care to Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2010 Report Share Posted November 5, 2010 Hi Jeanine, I have had mold exposures where I have had BOTH a toxic [non-allergic], and an allergic reaction during the same mold exposure. I have had other mold exposures where I have had ONLY an allergic reaction. And I have had other mold exposures where I have had ONLY a toxic reaction. My last mold exposure, a few weeks ago, lasted for only one hour. It was due to exposure to mold and/or mycotoxins clinging to the body and hair and clothing of two people still living in a toxic mold infested home. I felt fine during the one hour sitting opposite them, at a table in a diner. The fact that I did not feel sick in their presence, means that I DID NOT have an allergic reaction to their presence, as I would have been made immediately sick, if I had an " allergic " sensitivity to the mold/mycotoxins covering them. My reaction to them began 2 to 3 hours later, and peaked around 12 hours later, and disappeared 72 hours later. I am NOT saying that you can extrapolate this time ratio to all toxic mold reactions. I am just saying that if they had been covered with cat hair, my allergic reaction to cat hair would have not taken more than 5 minutes to start. I would have immediately began running away from them, and would have turned back to face them, from a distance of 15 feet, just long enough to yell at them: " I'll phone you with an explanation. " I am a great believer in " running first and explaining later " . My initial mold exposure, at a new job, many years ago, was a combination of both an allergic reaction and a toxic reaction. The onset of symptoms was slow, and as I had never heard of a " toxic " mold reaction, at that time, I misinterpreted it as just another allergic/asthmatic reaction. The reason that I did NOT get an IMMEDIATE allergy reaction, is because the mold was NOT in my employer's office, but was, instead in the remaining 95% of the abandoned building which had not yet been " cleaned up " and rented out. For anyone to get an allergic reaction, or asthmatic reaction, the person has to be in the same room as the triggering antigen [mold, cat hair etc.]. Unless the antigen is airborne, like mold spores or mycotoxins, and there is an OPEN DOOR between that antigen source and the allergy/asthma sufferer. In MY case, there was no such door or hallway connection to my work area, so the " allergy " onset was not " immediate " . A " toxic " mold reaction only requires that you be in the same building, or on the same building floor, if we are talking about an apartment building, if you are a mold " reactor " . A neighbor of mine, who lives eleven floors above me, has a mold infestation, which is probably of the " non-toxic " variety, because I can stand, for a few seconds, in the building hallway, outside his open apartment door, without getting either an allergic, or toxic, reaction. I once even spent an hour standing there, while he cleaned out junk from his apartment, and put it into 30 gallon trash bags that I was holding in the hallway. The mold stench is so overpowering, that I feel like throwing up, but, amazingly, no reaction of any sort. I assume that if I was ever stupid enough to actually enter his apartment, I would get an allergic reaction, but NOT a toxic reaction. As far as the speed of onset of symptoms, and the duration of those symptoms, my " yardstick " is the medical concept of: " If a medicine works, then the patient was suffering from the illness that the medicine is designed to treat. " The way I can tell what percentage of my combined " allergic/toxic " reactions was purely allergic is by the percentage of my previous suffering that has been relieved by my medications for asthma and allergy. If those medicines are making me feel 25% better [after I've permanently left the moldy environment], then it is an indication that my suffering was 25% allergic and 75% toxic. The short answer to your below question is " YES " . The answer to your question of whether I have ever had my Total IgE tested, is " NO " . I have never understood your obsession, and the obsession of many others on this board, as to the taking of " tests " to identify, qualify, and quantify, the extent of your suffering. I have simplified my own outlook on what I " HAVE TO KNOW " about my suffering. I ask myself: " Am I sick to my stomach, or am I sick as a dog, or am I sick to death " . As I get older (67) I try to simplify my life and my concerns. May I recommend " simplification " to all of you, my friends. God Bless, Joe .................................................................................\ .............. Posted by: " osisposis " jeaninem660@... Re: Toxin Help Joe, heres another question, are you allergic to the same molds that you also have a non-allergic reaction to? in other words, ever had both a allergic and non-allergic reaction to a mold and it's toxins at the same time? immediate reaction possabily lasting a few days plus delayed reactions starting in and lasting days to weeks,months? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 This is EXACTLY the reason for an " obsession " with tests: how do you know you don't have a delayed hypersensitivity (allergy)? You're assuming that a delayed reaction = response to toxins. A delayed reaction can also be an allergic response that is delayed. You may have immediate-type reactions to dander and delayed to mold. You just don't know. A lot of people also work themselves into a frenzy thinking xyz is true but even their reports of their symptoms don't add up (I'm not saying this is true if you). That's why independent verification can help. Sent from my iPhone On Nov 5, 2010, at 10:34 PM, Joe Salowitz <josephsalowitz@...> wrote: I have had mold exposures where I have had BOTH a toxic [non-allergic], and an allergic reaction during the same mold exposure. I have had other mold exposures where I have had ONLY an allergic reaction. And I have had other mold exposures where I have had ONLY a toxic reaction. My last mold exposure, a few weeks ago, lasted for only one hour. It was due to exposure to mold and/or mycotoxins clinging to the body and hair and clothing of two people still living in a toxic mold infested home. I felt fine during the one hour sitting opposite them, at a table in a diner. The fact that I did not feel sick in their presence, means that I DID NOT have an allergic reaction to their presence, as I would have been made immediately sick, if I had an " allergic " sensitivity to the mold/mycotoxins covering them. My reaction to them began 2 to 3 hours later, and peaked around 12 hours later, and disappeared 72 hours later. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 I suggest that you read up on Hypersensivities. Type I is IgE immediate and is true allergy. Types II, III and IV are not IgE (allergic) reactions. The British have added a fifth, Type V. The links are below for your edification. A person can have a mixture of the reactions with II, III, and IV being considered a toxic response, not an allergic response. http://www.cehs.siu.edu/fix/medmicro/hyper.htm http://www.masterdocs.com/fact_sheet_files/pdf/hypersensitivity.pdf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 Joe, thanks for the e-mail, I'm not sure why you went off the board, but thats ok. I, like you also really on my own experence but I also research to find answers to questions I dont have the answer to. tottal IgE might prove out to be a little more important than once thought, thats why I asked. or it could prove out to mean nothing. thank you for giving me your view, it's something to compare with my own, however you provided alot of info. that lead me to believe that you think I and many others are basicly ignorant, I dont think thats very fare of you to think that way exspecially sence as you said you rely tottally on your own experience and nothing else. to answer your question, I do research, thats why I am interested in things like tottal IgE and other testing people have had done. I like many here are very interested in hearing others experiences, there seems to be a patteren emerging to me that may go a long way in understanding some of the differences we have and some similarities. like while some may be very ill because of dreaded genes influence, some may be very ill from more the damage caused by the exposure on organs. some who also suffer allergies, some who do not. some who also suffer lyme disease, some who do not. I think what differs me and you in our difference of opinon on allergies and what role that may play, is that you look at only the old thoughts of what allergy is and how it affects, while I because of research understand that they just dont have all the answers there yet. some are looking at it closer, some are starting to think IgE may not be a great deturming facter, other cell functions are being looked at, even HLA is getting a closer look. there is inflammatory reactions with allergy along with other reactions and there may be interference in how a allergy reaction presents itself when combined with CNS damage, toxic reactions,ect. receptor disfunction could play a big role in how symptoms are seen. you dont have to be atopic to have a allergy, they are trying to find a cap on IgE related to atopic allergy vs non-atopic allergy. right now it looks like IgE infinity may only apply to atopics. which might explain why my last to tottal IgE count were very low, the last being 0. you can get a allergy with high dose exposure that may not be long lasting, which I believe explains me. several on this board are looking for answers, why? because they are still trying to understand what happened to them and what continues to happen. theres no dought in my mind, like you that yes, you can have both allergy and toxicity from these exposures, the difference is is that I had testing that you didn't and now I need answers to understand exactly what my medical records are showing me and how it all fits in with what I experienced. so, while I respect your thoughts and thanks for answering some of my questions, I dont tottally agree with you and because I dont agree with all the old thoughts about allergy, I've infact been pretty aggervated over the issue for quite some time because theres to many unanswered questions there. now I still get immediate reactions to many things, maybe not because of allergy, maybe because of the damage my organs suffered. allergic hypersensitivity vs. non allergic hypersensitivity. atopic allergy vs non-atopic allergy, immediate vs delayed. do I still have a allergy to the molds I was exposed to or has it subsided along with my tottal IgE count. I would ask that you please dont jump all over people in the future that come here talking about the allergy side of thier illness because it doesn't fit in with your thoughts on what you believe, we may learn something from them. can you do that for me? I'm not asking you to believe anything other than what you believe, I'm just asking that you set back and let people express theirself without jumping down their throat because they dont see things like you do. while I believe no one in a WDB exposure would make it out without some level of toxicity, I can see how some may suffer allergy over toxicity so if allergy treatment helps them thats great. some ,even with allergy might not be able to get help for that because of the damage from the toxicity, a possability. for example, lets say you have severe CNS damage which included demyelination of many nerves, definitly would mess with how our brain and body talk to each other, could possably cause buildup of receptors at the nerve endings, seems that could be inflammatory itself. I see histamine intolerance as a very possable factor. so just maybe even a allergy becomes problematic in some cases and doesn't present like one exspects. my point is the answers are not all there, we may learn something new everyday. also, why some say that allergy testing is useless, I dont believe that, I think it may prove out to be more useful than not. theres no dought in my mind that intradermal testing can and does show both allergic and non-allergic hypersensitivity. problem is not all can be tested for sofar. so maybe,just maybe intradermal testing of molds might not show only allergy but also toxicity,mycotoxin exposure. now before anyone jumps on this thought, consider dirty serum, lack of being able to actually do intradermal testing for mycotoxins directly, and remember that theres other toxins involved with WDB exposure. and with the dreaded genes, if mycotoxins are not reconized this might affect weither they would show theirself this way. so see, there could be many possabilities. you know whats crazy is that for a long time I thought MCS was the immediate reactions I suffered but it just didn't add up with what all others were saying. thing is, my specific IgE and IgG mold testing was done for MCS, part of the diagnoses of MCS, along with more intradermal testing and other testing for intolerences. gell and combs, AAEM, and allergy based,and intolerance based. I also have TE. so, I first had regular allergy testing from a ALLERGEST, highly allergic to many mold mixes, intradermal testing, than specific testing and diagnosed with MCS, than diagnosed with TE, and latest tottal IgE is 0. plus I had delayed reactions with the intradermal testing,every time yet I'm felling fairly confident that if I had intradermal testing for molds right now, back at that ALLERGEST office, I may very well still show has highly allergic to many mold mixes. I'm temped to go have it done just to see. what would that show if it did? what would it mean if it didn't? di I still have a allergy to molds, did I ever have a allergy to molds or was it non allergic hypersensitivity showing itself by allergy testing? and would allergy desensatation only help those with a true atopic allergy? left than the toxicity to deal with which could be anywhere on a bad scale depending on their exposure and to some small extent genitics, maybe a larger extent genitics if they have the dreaded types and possably other HLA genitics that inadvertly may play a role. interesting about antigen presentation pathways that both mycotoxins and allergens are presented by and some other toxins? I have to wonder if we are not looking at a whole picture here by not takeing as close of a look at the allergy side of this as maybe we should be. maybe by looking at allergy and toxicity together some answers might be found there. I have to wonder in my own case, what about my second WDB was so different than than the first exposure that it caused much more damage,tottal breakdown of all brain barriors, a allergy or non-allergic hypersensitivity that the first exposure didn't cause, severe stomach and bowel damage beyond the years of dierrhea from the first home exposure and also specific food intolerances that I didn't have with the first exposure. what I do know is the second home put me right in the path of not only years of mold and mold byproducts filth, but also high humidity and active mold growth, where the first home was mainly exposure to dried toxic mold dust. so you see, I have many unanswered questions, and I'm sorry but your beliefs just dont answer them for me. weither you are right or wrong remains to be proven, so I'm at a loss as to why you fell you have all the answers and everyone else is ignorant. this illness has no room for ego's, I've said that before and well say it again. and you only need to take a look at the past,and present to see that ego greatly interfers with finding answers. with helping to treat each individual case that if nothing else by now we should be able to see that one size doesn't fit all. one protocal doesn't fit all. personally I'm pretty fed up with everyone that claims to know all, what works for them has to work for others, this doc is great, this one isn't, and so on. it seems the focus has gone from actually helping us to some kind of sick need to be right, ego. I could care less who coined this or that, who needs a nobal prize, what names is put on a disease. kind of like the liveing in the desert therory, gee, that would just mess me up real good, the dryness, the sand particles, the dehydration, sand mold,sleeping outdoors with heat and cold changes, probably would develop a lung infection over that alone. so you see, no one has all the answers, not even Shoemaker. for ever protocal that works for someone, theres many it doesn't work for. actuall physical organ damage just keeps being ignored and depending on what it is or weither it can be operated on or not, plays a role for some, yet we have many that cant see beyond their own experiences to see some are injuried worse and in different ways that hender their recovery. I have little dought that I did have a infection with my second exposure and it went to my head and caused alot of damage on the way, those white streaks in the CSF draining out my nose and ears speaks for itself, my damaged spinal cord and olfactory bulb and tract on my left side and the damage suffered in that area, the obvious loss of frontal lobe and increased space between my brain and scaull, the ear problems and very bad lose of balance, the seizure type experiences that some exposures cause,ect. this is not something that any protocal is going to fix. advoidance doesn't fix it and extreme advoidance, what ever that is proclaimed to be doesn't fix it. IT ONLY KEEPS YOU FROM SUFFERING THE CONSTANT EFFECTS THAT RE-EXPOSURES CAUSE. and if your damn lucky and didn't suffer these types of injury it helps give your body a chance to heal, whats healable anyway. so, you see all the differences suffaceing here? dont you think you owe Jackie a BIG FAT SORRY ? 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Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 oh Joe, sorry,I see that did get posted to the board, just hadn't yet when I got the email. > Hi Jeanine, > > I have had mold exposures where I have had BOTH a toxic [non-allergic], and an allergic reaction during the same mold exposure. I Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 so what would a specific IgE type 2 to penicillium notatum mean? --- In , " Jack Thrasher, Ph.D. " <toxicologist1@...> wrote: > > I suggest that you read up on Hypersensivities. Type I is IgE immediate and is true allergy. Types II, III and IV are not IgE (allergic) reactions. The British have added a fifth, Type V. The links are below for your edification. A person can have a mixture of the reactions with II, III, and IV being considered a toxic response, not an allergic response. > > http://www.cehs.siu.edu/fix/medmicro/hyper.htm > > http://www.masterdocs.com/fact_sheet_files/pdf/hypersensitivity.pdf > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 I believe this all leads back to hypersensitivity reactions which can be immediate or can be delayed onset.   I have tested positive for allergy to mold, then negative to allergy to mold and even then I still have reactions to it so the alergy testing to me is worthless. I just go by how I feel like Joe. Run like heck if I have to if I walk into a contamination, exposure situation. If you are more aware of your reactions and your surroundings paying close attention you will be able to tell the difference as to when to go and when to run. God Bless !! dragonflymcs Mayleen ________________________________ From: Joe Salowitz <josephsalowitz@...> < > Sent: Fri, November 5, 2010 11:34:43 PM Subject: [] Re: Toxin Help   I have had mold exposures where I have had BOTH a toxic [non-allergic], and an allergic reaction during the same mold exposure. I have had other mold exposures where I have had ONLY an allergic reaction. And I have had other mold exposures where I have had ONLY a toxic reaction.  My last mold e Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 dragon fly, what type of allergy testing did you have? you know, there are other things that can cause IgE , other diseases to. never the less that doesn't rule out that some may suffer greatly with their allergies to molds. if someone says allergy desensatation helped them greatly, I'm not going to set hear and discount that based on my own beliefs. exspecially if I'm not 100 percent sure if I even have true allergy or not. > > I believe this all leads back to hypersensitivity reactions which can be > immediate or can be delayed onset. > >  >  I have tested positive for allergy to mold, then negative to allergy to mold > and even then I still have reactions to it so the alergy testing to me is > worthless. I just go by how I feel like Joe. Run like heck if I have to if I > walk into a contamination, exposure situation. If you are more aware of your > reactions and your surroundings paying close attention you will be able to tell > the difference as to when to go and when to run. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 There is not such thing as IgE type II. IgE is type I. Type II is a cytotoxic mechanism leading to certain autoimmune diseases, e.g. pemphigus, autoimmune hemolytic anemia, Good pasture's syndrome. These diseases are mediated by IgG-Immune complexes, not IgE immune complexes. If your doctor has told you that you have IgE type 2 reaction, then take the information I cited and give it to your doctor. The Type II, III and IV can be brought on by toxins. For example, antibodies to trichothenes and aflatoxins have been demonstrated to occur in humans. These IgG antibodies can reach concentrations in the blood where the form immune complexes that can lead to disease. If you do not understand the mechanism of antibody production by exposure to foreign chemicals I will briefly explain. It has been shown that several molecules of satratoxin G bind to one molecule of albumin. This alters the structure of the albumin so that the immune system sees the altered albumin as foreign. The altered albumin is referred to as a new antigenic determinant (NAD) Antibodies are made which is an attempt to rid the body of the NAD. The NAD directed antibodies can them be involved in immune complex diseases as mentioned above. Also, the foreign chemicals can bind to other proteins of the body causing a similar reaction to the other NADs. This scenario is old information dating back years. [] Re: Toxin Help so what would a specific IgE type 2 to penicillium notatum mean? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 so what would a specific IgE type 2 to penicillium notatum mean? a cytotoxic self effect from penicillium notatum allergen exposure? molecular mimicry at work? > > --- In , " Jack Thrasher, Ph.D. " <toxicologist1@> wrote: > > > > I suggest that you read up on Hypersensivities. Type I is IgE immediate and is true allergy. Types II, III and IV are not IgE (allergic) reactions. The British have added a fifth, Type V. The links are below for your edification. A person can have a mixture of the reactions with II, III, and IV being considered a toxic response, not an allergic response. > > > > http://www.cehs.siu.edu/fix/medmicro/hyper.htm > > > > http://www.masterdocs.com/fact_sheet_files/pdf/hypersensitivity.pdf > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2010 Report Share Posted November 6, 2010 must be a typo error than, thanks, been wondering about it but could find anything, so only other conclusion is typo error. --- In , " Jack Thrasher, Ph.D. " <toxicologist1@...> wrote: > > There is not such thing as IgE type II. IgE is type I. Type II is a cytotoxic mechanism leading to certain autoimmune diseases, e.g. pemphigus, autoimmune hemolytic anemia, Good pasture's syndrome. These diseases are mediated by IgG-Immune complexes, not IgE immune complexes. If your doctor has told you that you have IgE type 2 reaction, then take the information I cited and give it to your doctor. > > The Type II, III and IV can be brought on by toxins. For example, antibodies to trichothenes and aflatoxins have been demonstrated to occur in humans. These IgG antibodies can reach concentrations in the blood where the form immune complexes that can lead to disease. > If you do not understand the mechanism of antibody production by exposure to foreign chemicals I will briefly explain. > > It has been shown that several molecules of satratoxin G bind to one molecule of albumin. This alters the structure of the albumin so that the immune system sees the altered albumin as foreign. The altered albumin is referred to as a new antigenic determinant (NAD) Antibodies are made which is an attempt to rid the body of the NAD. The NAD directed antibodies can them be involved in immune complex diseases as mentioned above. Also, the foreign chemicals can bind to other proteins of the body causing a similar reaction to the other NADs. > > This scenario is old information dating back years. > > [] Re: Toxin Help > > > > so what would a specific IgE type 2 to penicillium notatum mean? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2010 Report Share Posted November 7, 2010 Absolutely right, Jack. This is what Dr. Marinkovich understood and treated. Its a form of serum sickness. _http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invoca tionType=ar1clk & flv=1_ (http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invocation\ Type=ar1clk & flv=1) I am also of the opinion that this is the cause of the rise in autism. Children used to get three vaccines. Now they get something like 27 or 28 causing a toxic overload that their little bodies cannot rid. In a message dated 11/6/2010 2:13:51 P.M. Pacific Standard Time, toxicologist1@... writes: There is not such thing as IgE type II. IgE is type I. Type II is a cytotoxic mechanism leading to certain autoimmune diseases, e.g. pemphigus, autoimmune hemolytic anemia, Good pasture's syndrome. These diseases are mediated by IgG-Immune complexes, not IgE immune complexes. If your doctor has told you that you have IgE type 2 reaction, then take the information I cited and give it to your doctor. The Type II, III and IV can be brought on by toxins. For example, antibodies to trichothenes and aflatoxins have been demonstrated to occur in humans. These IgG antibodies can reach concentrations in the blood where the form immune complexes that can lead to disease. If you do not understand the mechanism of antibody production by exposure to foreign chemicals I will briefly explain. It has been shown that several molecules of satratoxin G bind to one molecule of albumin. This alters the structure of the albumin so that the immune system sees the altered albumin as foreign. The altered albumin is referred to as a new antigenic determinant (NAD) Antibodies are made which is an attempt to rid the body of the NAD. The NAD directed antibodies can them be involved in immune complex diseases as mentioned above. Also, the foreign chemicals can bind to other proteins of the body causing a similar reaction to the other NADs. This scenario is old information dating back years. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2010 Report Share Posted November 7, 2010 Dr. Marinkovich was a very wise man. I am sure he his looking over us all. Children with autism have brain inflammation, much like other neurological diseases. Re: [] Re: Toxin Help Absolutely right, Jack. This is what Dr. Marinkovich understood and treated. Its a form of serum sickness. _http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invoca tionType=ar1clk & flv=1_ (http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invocation\ Type=ar1clk & flv=1) I am also of the opinion that this is the cause of the rise in autism. Children used to get three vaccines. Now they get something like 27 or 28 causing a toxic overload that their little bodies cannot rid. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2010 Report Share Posted November 7, 2010 levels 11-1V ,toxicity could be caused by internal causes with some disease could it not? or molecular mimicry, a allergy going systemic, possable? wouldn't a mold spore and whatever it contains or is attached it , possably also make it to the stomach if captured by mucus in the sinuses? doing some damage and haveing causeing some effects in the mucosal lineing in the sinuses before makeing it's way to the stomach? possably in some part makeing it into the blood stream,systemic,over time or with high dose exposure to mold spores. not talking about just one mold spore alone but continuous breathing in of mold spores, regarless of what else is involved. I know mold spores are bigger and dont make it to the brain. the mycotoxins can. maybe more so as damage increases to the mucosal barriors and tissue. > > Absolutely right, Jack. This is what Dr. Marinkovich understood and > treated. Its a form of serum sickness. > > _http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invoca > tionType=ar1clk & flv=1_ > (http://www.referencecenter.com/ref/reference/serumsic/serum_sickness?invocation\ Type=ar1clk & flv=1) > > I am also of the opinion that this is the cause of the rise in autism. > Children used to get three vaccines. Now they get something like 27 or 28 > causing a toxic overload that their little bodies cannot rid. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2010 Report Share Posted November 7, 2010 I had blood work, no skin pricking.  While exposed in my home my allergies were multiple to molds. This year I had allergy (blod work) They came back negative to all. Yet I have hypersensitivity reactions to many things, molds and chemicals. Including anaphlaxis to scents I have HP .  God Bless !! Mayleen _______________________________ From: osisposis <jeaninem660@...> dragon fly, what type of allergy testing did you have? you know, there are other things that can cause IgE , other diseases to. never the less that doesn't rule out that some may suffer greatly with their allergies to molds. if someone says allergy desensatation helped them greatly, I'm not going to set hear and discount that based on my own beliefs. exspecially if I'm not 100 percent sure if I even have true allergy or not. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2010 Report Share Posted November 7, 2010 so do you fell that now your sensitivitys are mainly non-allergic in nature? but you still have immediate reactions? whole body or only brain type responces? lung? sinus? stomach?<sometimes? have you been diagnosed with TE or MCS? > > I had blood work, no skin pricking.  While exposed in my home my allergies were > multiple to molds. This year I had allergy (blod work) They came back negative > to all. > > Yet I have hypersensitivity reactions to many things, molds and chemicals. > Including anaphlaxis to scents I have HP .  > > God Bless !! > Mayleen > > _______________________________ > From: osisposis <jeaninem660@...> > > dragon fly, what type of allergy testing did you have? > you know, there are other things that can cause IgE , other diseases to. never > the less that doesn't rule out that some may suffer greatly with their allergies > to molds. if someone says allergy desensatation helped them greatly, I'm not > going to set hear and discount that based on my own beliefs. exspecially if I'm > not 100 percent sure if I even have true allergy or not. > Quote Link to comment Share on other sites More sharing options...
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