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Re: Culturable mold indoor~association w/moisture-related problems~asthma~allergy

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It is not the spore count that they should be looking. They should have

included all of the contaminants in the building. The most likely association

would have been with the fine particulates, beta-glucans and the endotoxins.

Also, the Actinomycetes play an important role in respiratory disease, e.g.

hypersensitivity pneumonias. They are also present in the indoor air.

[] Culturable mold indoor~association w/moisture-related

problems~asthma~allergy

_http://www3.interscience.wiley.com/journal/123356386/abstract_

(http://www3.interscience.wiley.com/journal/123356386/abstract)

Culturable mold in indoor air and its association with moisture-related

problems and asthma and allergy among Swedish children

" No association could be found between the spore concentration in indoor

air and asthma/allergy in the children.

Practical Implications

Mold spore exposure indoor have been suggested as a possible explanation

for airway problems such as asthma and allergy among people living in

buildings with moisture-related problems. However, this investigation could

not

find any associations between the spore concentrations in indoor air and

signs of dampness and moldy odor reported by parents or observed by

professional inspectors. Neither was there any association between the indoor

spore

concentration and asthma/allergy among children. With these results, there

is no reason for one-time air sampling of mold colony-forming unit (CFU) in

indoor air of homes to identify risk factors for asthma/allergy in children

living in Scandinavian countries. "

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So very ridiculous. This is archaic thinking. I can only think of one reason a

study of total spore concentrations as it relates to health effects would be a

topic of research at this time. So much new research has shown that there are

so many other better indicators of health problems. Spore concentrations in the

air are a snapshot in time. Looking at settled spores, as well as other fungal

allergens and bacteria would be a better research topic.

Also, the concentration is not the important factor. Fungal profiles generally

shift in damp buildings. Fungi that amplify on cellulose building materials in

temperate indoor conditions are generally from the genera Aspergillus,

Penicillium, Chaetomium, and Stachybotrys, among others. The finding of a

predominance of these fungi in a few samples, or the pervasive presence in many

samples, even at low concentrations, are better indicators of health problems

than total fungal concentration.

If air samples are used, both culturable and countable (spore trap) should be

collected, and some means of generating normal living conditions should be

incorporated into the study. Yikes - did I just suggest aggressive sampling.

Absolutely!

Connie Morbach, M.S., CHMM, CIE

cleanlinest.com

Connie Morbach, M.S., CHMM, CIE

>

> _http://www3.interscience.wiley.com/journal/123356386/abstract_

> (http://www3.interscience.wiley.com/journal/123356386/abstract)

>

>

>

> Culturable mold in indoor air and its association with moisture-related

> problems and asthma and allergy among Swedish children

>

> " No association could be found between the spore concentration in indoor

> air and asthma/allergy in the children.

> Practical Implications

> Mold spore exposure indoor have been suggested as a possible explanation

> for airway problems such as asthma and allergy among people living in

> buildings with moisture-related problems. However, this investigation could

not

> find any associations between the spore concentrations in indoor air and

> signs of dampness and moldy odor reported by parents or observed by

> professional inspectors. Neither was there any association between the indoor

spore

> concentration and asthma/allergy among children. With these results, there

> is no reason for one-time air sampling of mold colony-forming unit (CFU) in

> indoor air of homes to identify risk factors for asthma/allergy in children

> living in Scandinavian countries. "

>

>

>

>

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I must again emphasize: Mold is only part of the problem. Bacteria are also

present. Both fungi and bacteria colonies shed fine particulates <1 micron that

contain with endo and exo metabolites. Other microbial by-products that

activate the innate immune system include glucans and endotoxins. The typical

exposure in a WDB is chronic low level of a mixture to toxins.

Jack-Dwayne: Thrasher, Ph.D.

Toxicologist/Immunotoxicologist/Fetaltoxicologist

www.drthrasher.org

toxicologist1@...

Off: 916-745-4703

Cell: 575-937-1150

L. Crawley, M.ED., LADC

Trauma Specialist

sandracrawley@...

916-745-4703 - Off

775-309-3994 - Cell

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