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Mycotoxins in indoor environments

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Mycotoxins in Indoor Environments

Determination using Mass Spectrometry

CONCLUSIONS

• GC-MSMS analysis of VER and TRID HFB-derivatives in NICI mode and HPLC-MSMS

analysis of STRG, SATG, SATH, GLIO, and AFLAB in positive ESI mode, using triple

quadrupole MS, are very specific and sensitive methods for analysis of indoor

environmental samples.

• The developed integrated HPLC- and GC-MSMS analysis strategy for the combined

analysis of all indicated mycotoxins is convenient and applicable especially

when sample size is small.

• Molds in water-damaged indoor environments, in both sub-tropic and tempered

climatic zones, produce mycotoxins regularly. Mycotoxins were found in settled

dust on surfaces above floor level indicating that mycotoxins from

mold-contaminated building materials can become airborne and inhalable.

• Mycotoxin production or prevalence does not seem to correlate to microscopy

findings, CFU counts, or PCR results for fungi. There is a potential correlation

between fungal biomass and mycotoxin production.

- 59

http://lup.lub.lu.se/luur/download?func=downloadFile & recordOId=1265413 & fileOId=1\

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